Spero Therapeutics, Inc.

SPRO Net buying

CIK 0001701108 #4540 in the set updated 21 Sep 2026

Bought (120 mo)

$44.50M

out of their own pocket, the only kind of buying there is

Sold (120 mo)

$17.95M

$115.47K on a plan · $1.18M straight out of an exercise

Sold at will

$16.66M

53 of 81 sales

Net

+$26.55M

+$27.84M against sales at will

By person

22 insiders · 115 transactions

Insider

Role

Bought

Sold

Net

Holding

Of company

Worth

Change

GSK plc entity

10% owner

$7.00M (2)

—

+$7.00M

3,788,012

6.50%

$9.51M

+104.3%

Aquilo Capital Management, LLC entity

10% owner

$22.41M (27)

$15.42M (13)

+$7.00M

11,513,987

19.77%

$28.90M

−8.6%

FORMELA JEAN FRANCOIS

Director

$6.00M (1)

—

+$6.00M

2,408,128

4.14%

$6.04M

+5,529%

Goyal Vikas

Director

$6.00M (1)

—

+$6.00M

1,854,006

3.18%

$4.65M

—

Breum Casper

Director

$3.00M (1)

—

+$3.00M

1,091,774

1.87%

$2.74M

—

Mahadevia Ankit

Director

—

$1.04M (28) scheduled

−$1.04M

703,294

1.21%

$1.77M

+968.6%

Rajavelu Esther

See Remarks

—

$475.99K (8)

−$475.99K

986,851

1.69%

$2.48M

—

Shukla Sath

CEO & President

—

$305.74K (12)

−$305.74K

1,736,883

2.98%

$4.36M

—

Larkin Cristina

Chief Operating Officer

$21.00K (1)

$298.00K (2) scheduled

−$277.00K

63,581

0.1092%

$159.59K

—

Keutzer Timothy

Chief Operating Officer

—

$246.39K (12)

−$246.39K

742,506

1.28%

$1.86M

+29,600%

HAMED KAMAL

Chief Medical Officer

—

$88.62K (2)

−$88.62K

788,117

1.35%

$1.98M

—

JOSEPH TAMARA L

Chief Legal Officer

—

$50.99K (3)

−$50.99K

531,615

0.9129%

$1.33M

—

Sendek Joel

Chief Financial Officer

$70.00K (1)

$35.00K (1) scheduled

+$35.00K

25,362

0.0436%

$63.66K

+149.1%

Zack Debra

Chief Medical Officer

—

—

—

162,311

0.2787%

$407.40K

—

Deshpande Milind

Director

—

—

—

101,454

0.1742%

$254.65K

+516.6%

Tregoning Kathleen

Director

—

—

—

85,000

0.1460%

$213.35K

—

Smith Cynthia

Director

—

—

—

85,000

0.1460%

$213.35K

—

THOMAS FRANK E

Director

—

—

—

85,000

0.1460%

$213.35K

—

Jackson Scott Thomas

Director

—

—

—

85,000

0.1460%

$213.35K

—

VINK PATRICK V.J.J.

Director

—

—

—

85,000

0.1460%

$213.35K

—

Pottage John C Jr

Director

—

—

—

85,000

0.1460%

$213.35K

—

Melnick David A.

Chief Medical Officer

—

—

—

62,081

0.1066%

$155.82K

—

Individual transactions

0

Nothing of that kind in this period.

What was left out

Form 4 filings counted 197

Amendments (4/A) skipped 0

Filings about a different issuer 0

Unreadable filings 0

Joint filings 23

Sales on a Rule 10b5-1 plan 4

Sales straight out of an exercise 24

Sales at will 53

Transactions with no price 0

Shares from compensation/vesting 13,007,082

Sales filed before the plan box existed 18

History held since 7 Nov 2017