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Upstream Bio, Inc.

UPB Net selling

CIK 0002022626 #3343 in the set updated 21 Sep 2026

Bought (12 mo)

$0.00

out of their own pocket, the only kind of buying there is

Sold (12 mo)

$104.80K

$0.00 on a plan · $0.00 straight out of an exercise

Sold at will

$104.80K

15 of 15 sales

Net

−$104.80K

−$104.80K against sales at will

By person

9 insiders · 15 transactions

Insider

Role

Bought

Sold

Net

Holding

Of company

Worth

Change

Sutherland Everett Rand

Chief Executive Officer

—

$43.73K (3)

−$43.73K

68,717

0.1255%

$377.26K

—

Deykin Aaron

Chief Medical Officer

—

$18.68K (3)

−$18.68K

32,302

0.0590%

$177.34K

+981.8%

GRAY MICHAEL

CFO and COO

—

$17.80K (3)

−$17.80K

27,942

0.0510%

$153.40K

—

Houghton Adam

Chief Business Officer

—

$14.61K (3)

−$14.61K

22,901

0.0418%

$125.73K

—

Ambrose Allison

General Counsel

—

$9.99K (3)

−$9.99K

15,563

0.0284%

$85.44K

—

AI Upstream LLC entity

10% owner

—

5,494,410

10.03%

$30.16M

—

ORBIMED ADVISORS LLC entity

Director

—

4,554,873

8.32%

$25.01M

+3,693%

Chimovits Erez

Director

—

4,554,873

8.32%

$25.01M

+3,693%

Wellington Biomedical Innovation Master Investors (Cayman) II L.P.

10% owner

—

894,733

1.63%

$4.91M

—

Individual transactions

Nothing of that kind in this period.

What was left out

Form 4 filings counted 26

Amendments (4/A) skipped 0

Filings about a different issuer 0

Unreadable filings 0

Joint filings 0

Sales on a Rule 10b5-1 plan 0

Sales straight out of an exercise 0

Sales at will 15

Transactions with no price 0

Shares from compensation/vesting 179,500

History held since 15 Oct 2024