InsiderClue
← All stocks

Upstream Bio, Inc.

UPB Net buying
CIK 0002022626 #3343 in the set updated 22 Sep 2026
Bought (120 mo)
$48.03M
out of their own pocket, the only kind of buying there is
Sold (120 mo)
$104.80K
$0.00 on a plan · $0.00 straight out of an exercise
Sold at will
$104.80K
15 of 15 sales
Net
+$47.92M
+$47.92M against sales at will

By person

9 insiders · 20 transactions
Insider
Role
Bought
Sold
Net
Holding
Of company
Worth
Change
AI Upstream LLC entity
10% owner
$19.98M (1)
—
+$19.98M
5,494,410
10.03%
$30.16M
—
Chimovits Erez
Director
$14.03M (2)
—
+$14.03M
4,554,873
8.32%
$25.01M
+3,693%
ORBIMED ADVISORS LLC entity
Director
$14.03M (2)
—
+$14.03M
4,554,873
8.32%
$25.01M
+3,693%
Sutherland Everett Rand
Chief Executive Officer
—
$43.73K (3)
−$43.73K
68,717
0.1255%
$377.26K
—
Deykin Aaron
Chief Medical Officer
—
$18.68K (3)
−$18.68K
32,302
0.0590%
$177.34K
+981.8%
GRAY MICHAEL
CFO and COO
—
$17.80K (3)
−$17.80K
27,942
0.0510%
$153.40K
—
Houghton Adam
Chief Business Officer
—
$14.61K (3)
−$14.61K
22,901
0.0418%
$125.73K
—
Ambrose Allison
General Counsel
—
$9.99K (3)
−$9.99K
15,563
0.0284%
$85.44K
—
Wellington Biomedical Innovation Master Investors (Cayman) II L.P.
10% owner
—
—
—
894,733
1.63%
$4.91M
—

Individual transactions

15
Insider
Date
Role
Action
Shares
Price
Amount
Ambrose Allison
16 Sep 2026
General Counsel
Sell
485
$5.49
$2.66K
Houghton Adam
16 Sep 2026
Chief Business Officer
Sell
700
$5.49
$3.84K
Sutherland Everett Rand
16 Sep 2026
Chief Executive Officer
Sell
2,095
$5.49
$11.50K
Deykin Aaron
16 Sep 2026
Chief Medical Officer
Sell
895
$5.49
$4.91K
GRAY MICHAEL
16 Sep 2026
CFO and COO
Sell
853
$5.49
$4.68K
Ambrose Allison
16 Jun 2026
General Counsel
Sell
477
$6.10
$2.91K
Deykin Aaron
16 Jun 2026
Chief Medical Officer
Sell
895
$6.10
$5.46K
Houghton Adam
16 Jun 2026
Chief Business Officer
Sell
700
$6.10
$4.27K
Sutherland Everett Rand
16 Jun 2026
Chief Executive Officer
Sell
2,095
$6.10
$12.78K
GRAY MICHAEL
16 Jun 2026
CFO and COO
Sell
853
$6.10
$5.20K
Houghton Adam
16 Mar 2026
Chief Business Officer
Sell
699
$9.29
$6.49K
Ambrose Allison
16 Mar 2026
General Counsel
Sell
475
$9.29
$4.41K
Sutherland Everett Rand
16 Mar 2026
Chief Executive Officer
Sell
2,093
$9.29
$19.44K
Deykin Aaron
16 Mar 2026
Chief Medical Officer
Sell
894
$9.29
$8.31K
GRAY MICHAEL
16 Mar 2026
CFO and COO
Sell
852
$9.29
$7.92K
Show all 20 transactions →

What was left out

Form 4 filings counted 48
Amendments (4/A) skipped 0
Filings about a different issuer 0
Unreadable filings 0
Joint filings 2
Sales on a Rule 10b5-1 plan 0
Sales straight out of an exercise 0
Sales at will 15
Transactions with no price 0
Shares from compensation/vesting 12,613,221
History held since 15 Oct 2024