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Denali Therapeutics Inc.

DNLI Net selling
CIK 0001714899 #1526 in the set updated 17 Sep 2026
Bought (120 mo)
$4.95M
out of their own pocket, the only kind of buying there is
Sold (120 mo)
$467.90M
$6.64M on a plan · $28.04M straight out of an exercise
Sold at will
$433.22M
387 of 501 sales
Net
−$462.95M
−$428.27M against sales at will

By person

22 insiders · 516 transactions
Insider
Role
Bought
Sold
Net
Holding
Of company
Worth
Change
BRATTON DOUGLAS K
10% owner
$4.95M (1)
$335.63M (19)
−$330.68M
9,984,836
6.25%
$222.56M
+3,095%
Watts Ryan J.
President and CEO
—
$41.18M (122)
−$41.18M
2,417,217
1.51%
$53.88M
−19.2%
Tessier-Lavigne Marc
Director
—
$36.20M (40)
−$36.20M
1,965,424
1.23%
$43.81M
−28.8%
Schuth Alexander O.
COFO and Secretary
—
$18.46M (121)
−$18.46M
1,342,051
0.8396%
$29.91M
+1.1%
Krognes Steve E.
Director
—
$15.19M (37)
−$15.19M
888,202
0.5557%
$19.80M
+41.2%
Ho Carole
Chief Medical Officer
—
$11.29M (101) scheduled
−$11.29M
415,362
0.2598%
$9.26M
−5.8%
Schenkein David P
Director
—
$7.84M (7)
−$7.84M
47,897
0.0300%
$1.07M
—
SATO VICKI L
Director
—
$1.78M (50)
−$1.78M
107,976
0.0675%
$2.41M
+38.0%
Thornberry Nancy
Director
—
$261.93K (2) scheduled
−$261.93K
19,686
0.0123%
$438.80K
+944.9%
Chin Peter Scott
Chief Medical Officer
—
$36.87K (1)
−$36.87K
204,538
0.1280%
$4.56M
−0.8%
Cook Jennifer E.
Director
—
$31.68K (1) scheduled
−$31.68K
32,483
0.0203%
$724.05K
—
ARCH Venture Fund VIII, L.P. entity
10% owner
—
—
—
10,668,749
6.67%
$237.81M
+3,314%
NELSEN ROBERT
Director
—
—
—
9,681,181
6.06%
$215.79M
+2,998%
Flagship Ventures Fund V, L.P. entity
10% owner
—
—
—
8,918,749
5.58%
$198.80M
+2,754%
BAKER BROS. ADVISORS LP entity
Director
—
—
—
3,422,366
2.14%
$76.28M
+1.0%
FIL Ltd entity
See Remark 1
—
—
—
1,916,212
1.20%
$42.71M
—
FLATLEY JAY T
Director
—
—
—
363,157
0.2272%
$8.09M
+358.4%
Klein Peter S
Director
—
—
—
33,941
0.0212%
$756.54K
—
FMR LLC entity
See Remark 1
—
—
—
33,215
0.0208%
$740.36K
—
Cole Douglas G.
Director
—
—
—
26,564
0.0166%
$592.11K
+140.7%
Harris Erik
Director
—
—
—
17,052
0.0107%
$380.09K
—
Van Hauwermeiren Timothy
Director
—
—
—
17,040
0.0107%
$379.82K
—

Individual transactions

170
Insider
Date
Role
Action
Shares
Price
Amount
Chin Peter Scott
4 Sep 2026
Chief Medical Officer
Sell
1,654
$22.29
$36.87K
Schuth Alexander O.
11 Aug 2026
COFO and Secretary
Sell
2,857
$25.07
$71.62K
Schuth Alexander O.
6 Jan 2026
COFO and Secretary
Sell
17,218
$16.50
$284.10K
Watts Ryan J.
6 Jan 2026
President and CEO
Sell
35,198
$16.50
$580.77K
Schuth Alexander O.
12 Aug 2025
COFO and Secretary
Sell
2,937
$13.58
$39.88K
Krognes Steve E.
7 Jan 2025
Director
Sell
3,339
$20.81
$69.48K
Watts Ryan J.
7 Jan 2025
President and CEO
Sell
7,650
$20.81
$159.20K
Schuth Alexander O.
7 Jan 2025
COFO and Secretary
Sell
2,907
$20.81
$60.49K
Ho Carole
7 Jan 2025
Chief Medical Officer
Sell
2,907
$20.81
$60.49K
Watts Ryan J.
6 Jan 2025
President and CEO
Sell
29,266
$20.22
$591.76K
Schuth Alexander O.
6 Jan 2025
COFO and Secretary
Sell
12,255
$20.22
$247.80K
Ho Carole
6 Jan 2025
Chief Medical Officer
Sell
12,255
$20.22
$247.80K
Krognes Steve E.
20 Aug 2024
Director
Sell
1,727
$23.79
$41.09K
Watts Ryan J.
20 Aug 2024
President and CEO
Sell
2,260
$23.79
$53.77K
Ho Carole
13 Aug 2024
Chief Medical Officer
Sell
2,337
$22.89
$53.49K
Schuth Alexander O.
13 Aug 2024
COFO and Secretary
Sell
2,272
$22.89
$52.01K
Watts Ryan J.
13 Feb 2024
President and CEO
Sell
9,589
$17.29
$165.79K
Krognes Steve E.
13 Feb 2024
Director
Sell
2,750
$17.29
$47.55K
Watts Ryan J.
9 Jan 2024
President and CEO
Sell indirect
7,818
$19.78
$154.64K
Watts Ryan J.
5 Jan 2024
President and CEO
Sell indirect
17,483
$19.43
$339.69K
Schuth Alexander O.
5 Jan 2024
COFO and Secretary
Sell indirect
9,972
$19.43
$193.76K
Krognes Steve E.
5 Jan 2024
Director
Sell
3,208
$19.43
$62.33K
Ho Carole
5 Jan 2024
Chief Medical Officer
Sell indirect
9,972
$19.43
$193.76K
Ho Carole
23 Aug 2023
Chief Medical Officer
Sell indirect
2,522
$23.22
$58.56K
Schuth Alexander O.
23 Aug 2023
COFO and Secretary
Sell indirect
2,522
$23.17
$58.43K
Krognes Steve E.
21 Aug 2023
Director
Sell
1,419
$22.60
$32.07K
Watts Ryan J.
21 Aug 2023
President and CEO
Sell indirect
2,309
$22.59
$52.16K
Schuth Alexander O.
21 Aug 2023
COFO and Secretary
Sell indirect
2,478
$22.59
$55.98K
Ho Carole
21 Aug 2023
Chief Medical Officer
Sell indirect
2,478
$22.60
$56.00K
Schuth Alexander O.
14 Aug 2023
COFO and Secretary
Sell indirect
2,772
$23.67
$65.61K
Schuth Alexander O.
10 Aug 2023
COFO and Secretary
Sell indirect
2,853
$24.18
$68.99K
Ho Carole
10 Aug 2023
Chief Medical Officer
Sell indirect
2,857
$24.15
$69.00K
Schuth Alexander O.
18 Jul 2023
COFO and Secretary
Sell indirect
9,702
$30.01
$291.16K
Ho Carole
15 Feb 2023
Chief Medical Officer
Sell indirect
1,476
$29.40
$43.39K
Ho Carole
13 Feb 2023
Chief Medical Officer
Sell indirect
2,548
$30.10
$76.69K
Krognes Steve E.
13 Feb 2023
Director
Sell
2,119
$30.10
$63.78K
Ho Carole
10 Feb 2023
Chief Medical Officer
Sell indirect
818
$29.80
$24.38K
Watts Ryan J.
9 Feb 2023
President and CEO
Sell indirect
3,433
$30.59
$105.02K
Krognes Steve E.
8 Feb 2023
Director
Sell
1,377
$30.88
$42.52K
Schuth Alexander O.
8 Feb 2023
COFO and Secretary
Sell indirect
1,521
$30.89
$46.98K
Ho Carole
8 Feb 2023
Chief Medical Officer
Sell indirect
1,521
$30.88
$46.97K
Ho Carole
9 Jan 2023
Chief Medical Officer
Sell indirect
1,459
$28.48
$41.55K
Ho Carole
6 Jan 2023
Chief Medical Officer
Sell indirect
1,451
$28.67
$41.60K
Watts Ryan J.
5 Jan 2023
President and CEO
Sell indirect
4,800
$28.44
$136.51K
Schuth Alexander O.
5 Jan 2023
COFO and Secretary
Sell indirect
2,636
$28.44
$74.97K
Krognes Steve E.
5 Jan 2023
Director
Sell
2,970
$28.44
$84.47K
Ho Carole
5 Jan 2023
Chief Medical Officer
Sell indirect
2,636
$28.44
$74.97K
Watts Ryan J.
4 Jan 2023
President and CEO
Sell indirect
5,029
$28.73
$144.48K
Schuth Alexander O.
4 Jan 2023
COFO and Secretary
Sell
2,912
$28.70
$83.57K
Ho Carole
4 Jan 2023
Chief Medical Officer
Sell indirect
2,913
$28.69
$83.57K
Tessier-Lavigne Marc
23 Nov 2022
Director
Sell
20,000
$30.48
$609.60K
Tessier-Lavigne Marc
2 Nov 2022
Director
Sell
11,252
$30.33
$341.27K
Tessier-Lavigne Marc
1 Nov 2022
Director
Sell
8,748
$30.20
$264.19K
Tessier-Lavigne Marc
28 Sep 2022
Director
Sell
4,423
$31.08
$137.47K
Tessier-Lavigne Marc
28 Sep 2022
Director
Sell
15,577
$30.74
$478.84K
Ho Carole
23 Aug 2022
Chief Medical Officer
Sell indirect
2,424
$31.98
$77.52K
Tessier-Lavigne Marc
23 Aug 2022
Director
Sell
100
$32.43
$3.24K
Tessier-Lavigne Marc
23 Aug 2022
Director
Sell
19,900
$31.61
$629.04K
Ho Carole
19 Aug 2022
Chief Medical Officer
Sell indirect
2,576
$33.22
$85.57K
Schuth Alexander O.
19 Aug 2022
COFO and Secretary
Sell indirect
2,576
$33.22
$85.57K
Krognes Steve E.
19 Aug 2022
Director
Sell
2,253
$33.22
$74.84K
Watts Ryan J.
19 Aug 2022
President and CEO
Sell indirect
2,404
$33.22
$79.86K
Tessier-Lavigne Marc
25 Jul 2022
Director
Sell
200
$36.15
$7.23K
Tessier-Lavigne Marc
25 Jul 2022
Director
Sell
19,800
$35.60
$704.88K
Tessier-Lavigne Marc
23 Mar 2022
Director
Sell
11,598
$34.14
$395.96K
Tessier-Lavigne Marc
23 Mar 2022
Director
Sell
8,402
$33.40
$280.63K
Ho Carole
11 Feb 2022
Chief Medical Officer
Sell indirect
2,918
$34.71
$101.28K
Schuth Alexander O.
11 Feb 2022
COO and Secretary
Sell indirect
2,803
$34.68
$97.21K
Krognes Steve E.
11 Feb 2022
CFO and Treasurer
Sell
2,560
$34.69
$88.81K
Watts Ryan J.
11 Feb 2022
President and CEO
Sell indirect
9,491
$34.72
$329.53K
Ho Carole
9 Feb 2022
Chief Medical Officer
Sell indirect
1,423
$37.10
$52.79K
Schuth Alexander O.
9 Feb 2022
COO and Secretary
Sell indirect
1,423
$37.10
$52.80K
Watts Ryan J.
9 Feb 2022
President and CEO
Sell indirect
2,719
$37.55
$102.10K
Krognes Steve E.
9 Feb 2022
CFO and Treasurer
Sell
1,296
$37.09
$48.07K
Schuth Alexander O.
5 Jan 2022
COO and Secretary
Sell indirect
2,846
$44.77
$127.42K
Ho Carole
5 Jan 2022
Chief Medical Officer
Sell indirect
2,845
$44.78
$127.40K
Krognes Steve E.
5 Jan 2022
CFO and Treasurer
Sell
2,225
$44.75
$99.57K
Watts Ryan J.
5 Jan 2022
President and CEO
Sell indirect
5,007
$44.78
$224.21K
Tessier-Lavigne Marc
30 Dec 2021
Director
Sell indirect
800
$45.72
$36.58K
Tessier-Lavigne Marc
30 Dec 2021
Director
Sell indirect
6,002
$45.31
$271.95K
Tessier-Lavigne Marc
30 Dec 2021
Director
Sell indirect
900
$45.71
$41.14K
Tessier-Lavigne Marc
30 Dec 2021
Director
Sell indirect
5,625
$45.31
$254.87K
Tessier-Lavigne Marc
30 Dec 2021
Director
Sell indirect
3,377
$45.59
$153.96K
Tessier-Lavigne Marc
30 Dec 2021
Director
Sell indirect
3,343
$45.13
$150.87K
Tessier-Lavigne Marc
29 Dec 2021
Director
Sell indirect
10,704
$43.88
$469.69K
Tessier-Lavigne Marc
29 Dec 2021
Director
Sell indirect
10,700
$43.87
$469.41K
Tessier-Lavigne Marc
29 Dec 2021
Director
Sell indirect
10,700
$43.88
$469.52K
Tessier-Lavigne Marc
28 Dec 2021
Director
Sell indirect
3,646
$44.37
$161.77K
Tessier-Lavigne Marc
28 Dec 2021
Director
Sell indirect
3,602
$44.38
$159.86K
Tessier-Lavigne Marc
28 Dec 2021
Director
Sell indirect
3,732
$44.37
$165.59K
Ho Carole
6 Dec 2021
Chief Medical Officer
Sell
1,476
$42.52
$62.76K
Schuth Alexander O.
6 Dec 2021
COO and Secretary
Sell indirect
7,200
$42.45
$305.64K
Schuth Alexander O.
6 Dec 2021
COO and Secretary
Sell indirect
2,800
$41.82
$117.10K
Watts Ryan J.
1 Dec 2021
President and CEO
Sell indirect
805
$46.35
$37.31K
Watts Ryan J.
1 Dec 2021
President and CEO
Sell indirect
9,012
$45.30
$408.24K
Watts Ryan J.
1 Dec 2021
President and CEO
Sell indirect
8,516
$44.39
$378.03K
SATO VICKI L
10 Nov 2021
Director
Sell
660
$53.30
$35.18K
SATO VICKI L
10 Nov 2021
Director
Sell
1,006
$52.49
$52.80K
Schuth Alexander O.
4 Nov 2021
COO and Secretary
Sell indirect
3,283
$53.23
$174.75K
Schuth Alexander O.
4 Nov 2021
COO and Secretary
Sell indirect
6,717
$52.65
$353.65K
SATO VICKI L
1 Nov 2021
Director
Sell
1,666
$50.05
$83.38K
Watts Ryan J.
1 Nov 2021
President and CEO
Sell indirect
16,674
$49.87
$831.53K
Watts Ryan J.
1 Nov 2021
President and CEO
Sell indirect
1,659
$48.61
$80.64K
Schuth Alexander O.
4 Oct 2021
COO and Secretary
Sell indirect
4,006
$51.04
$204.47K
Schuth Alexander O.
4 Oct 2021
COO and Secretary
Sell indirect
5,994
$50.24
$301.14K
Watts Ryan J.
1 Oct 2021
President and CEO
Sell indirect
4,247
$50.99
$216.55K
Watts Ryan J.
1 Oct 2021
President and CEO
Sell indirect
10,782
$50.44
$543.84K
Watts Ryan J.
1 Oct 2021
President and CEO
Sell indirect
3,304
$49.38
$163.15K
SATO VICKI L
15 Sep 2021
Director
Sell
140
$54.76
$7.67K
SATO VICKI L
15 Sep 2021
Director
Sell
620
$53.92
$33.43K
SATO VICKI L
15 Sep 2021
Director
Sell
676
$53.03
$35.85K
SATO VICKI L
15 Sep 2021
Director
Sell
230
$52.28
$12.02K
Schuth Alexander O.
7 Sep 2021
COO and Secretary
Sell indirect
2,441
$56.05
$136.82K
Schuth Alexander O.
7 Sep 2021
COO and Secretary
Sell indirect
5,350
$55.67
$297.83K
Schuth Alexander O.
7 Sep 2021
COO and Secretary
Sell indirect
2,209
$54.70
$120.83K
Watts Ryan J.
1 Sep 2021
President and CEO
Sell indirect
10,892
$54.92
$598.19K
Watts Ryan J.
1 Sep 2021
President and CEO
Sell indirect
7,441
$54.27
$403.82K
Ho Carole
23 Aug 2021
Chief Medical Officer
Sell indirect
6,143
$48.91
$300.45K
Krognes Steve E.
19 Aug 2021
CFO and Treasurer
Sell
200
$50.07
$10.01K
Krognes Steve E.
19 Aug 2021
CFO and Treasurer
Sell
2,085
$49.52
$103.25K
Watts Ryan J.
19 Aug 2021
President and CEO
Sell indirect
750
$49.97
$37.48K
Watts Ryan J.
19 Aug 2021
President and CEO
Sell indirect
1,626
$49.38
$80.29K
Schuth Alexander O.
19 Aug 2021
COO and Secretary
Sell indirect
196
$50.10
$9.82K
Schuth Alexander O.
19 Aug 2021
COO and Secretary
Sell indirect
2,348
$49.56
$116.37K
Ho Carole
19 Aug 2021
Chief Medical Officer
Sell indirect
1,144
$49.91
$57.10K
Ho Carole
19 Aug 2021
Chief Medical Officer
Sell indirect
1,402
$49.31
$69.13K
SATO VICKI L
18 Aug 2021
Director
Sell
860
$52.12
$44.82K
SATO VICKI L
18 Aug 2021
Director
Sell
806
$51.26
$41.32K
Schuth Alexander O.
4 Aug 2021
COO and Secretary
Sell indirect
200
$52.99
$10.60K
Schuth Alexander O.
4 Aug 2021
COO and Secretary
Sell indirect
8,236
$52.34
$431.06K
Schuth Alexander O.
4 Aug 2021
COO and Secretary
Sell indirect
1,564
$51.52
$80.57K
Watts Ryan J.
2 Aug 2021
President and CEO
Sell indirect
9,790
$51.94
$508.49K
Watts Ryan J.
2 Aug 2021
President and CEO
Sell indirect
8,543
$50.80
$433.98K
SATO VICKI L
21 Jul 2021
Director
Sell
400
$65.78
$26.31K
SATO VICKI L
21 Jul 2021
Director
Sell
866
$65.24
$56.50K
SATO VICKI L
21 Jul 2021
Director
Sell
400
$64.25
$25.70K
Schuth Alexander O.
6 Jul 2021
COO and Secretary
Sell indirect
10,000
$76.20
$762.04K
Watts Ryan J.
1 Jul 2021
President and CEO
Sell indirect
2,459
$77.84
$191.40K
Watts Ryan J.
1 Jul 2021
President and CEO
Sell indirect
12,844
$77.35
$993.47K
Watts Ryan J.
1 Jul 2021
President and CEO
Sell indirect
3,030
$76.38
$231.43K
SATO VICKI L
23 Jun 2021
Director
Sell
986
$71.11
$70.11K
SATO VICKI L
23 Jun 2021
Director
Sell
680
$70.20
$47.74K
Schuth Alexander O.
4 Jun 2021
COO and Secretary
Sell indirect
4,340
$64.82
$281.30K
Schuth Alexander O.
4 Jun 2021
COO and Secretary
Sell indirect
5,660
$64.35
$364.20K
Watts Ryan J.
1 Jun 2021
President and CEO
Sell indirect
354
$63.50
$22.48K
Watts Ryan J.
1 Jun 2021
President and CEO
Sell indirect
2,102
$62.76
$131.91K
Watts Ryan J.
1 Jun 2021
President and CEO
Sell indirect
2,750
$62.09
$170.75K
Watts Ryan J.
1 Jun 2021
President and CEO
Sell indirect
13,127
$60.98
$800.51K
SATO VICKI L
26 May 2021
Director
Sell
40
$66.72
$2.67K
SATO VICKI L
26 May 2021
Director
Sell
732
$65.88
$48.22K
SATO VICKI L
26 May 2021
Director
Sell
894
$64.90
$58.02K
Tessier-Lavigne Marc
24 May 2021
Director
Sell
8,806
$60.03
$528.58K
Tessier-Lavigne Marc
21 May 2021
Director
Sell
37,957
$60.13
$2.28M
Schuth Alexander O.
4 May 2021
COO and Secretary
Sell indirect
445
$57.39
$25.54K
Schuth Alexander O.
4 May 2021
COO and Secretary
Sell indirect
3,557
$55.92
$198.89K
Schuth Alexander O.
4 May 2021
COO and Secretary
Sell indirect
5,998
$55.09
$330.44K
Watts Ryan J.
3 May 2021
President and CEO
Sell indirect
851
$59.92
$50.99K
Watts Ryan J.
3 May 2021
President and CEO
Sell indirect
3,485
$59.12
$206.03K
Watts Ryan J.
3 May 2021
President and CEO
Sell indirect
13,997
$58.45
$818.08K
Tessier-Lavigne Marc
3 May 2021
Director
Sell
98
$61.20
$6.00K
Tessier-Lavigne Marc
3 May 2021
Director
Sell
3,139
$60.08
$188.59K
SATO VICKI L
28 Apr 2021
Director
Sell
688
$63.03
$43.37K
SATO VICKI L
28 Apr 2021
Director
Sell
597
$62.05
$37.04K
SATO VICKI L
28 Apr 2021
Director
Sell
381
$60.71
$23.13K
Schuth Alexander O.
5 Apr 2021
COO and Secretary
Sell indirect
700
$57.44
$40.21K
Schuth Alexander O.
5 Apr 2021
COO and Secretary
Sell indirect
4,156
$56.47
$234.67K
Schuth Alexander O.
5 Apr 2021
COO and Secretary
Sell indirect
5,144
$55.60
$286.03K
Watts Ryan J.
1 Apr 2021
President and CEO
Sell indirect
4,586
$57.31
$262.84K
Watts Ryan J.
1 Apr 2021
President and CEO
Sell indirect
8,516
$56.88
$484.36K
Watts Ryan J.
1 Apr 2021
President and CEO
Sell indirect
5,232
$55.52
$290.49K
Showing 250 of 516 transactions. The figures above use every one of them.

What was left out

Form 4 filings counted 397
Amendments (4/A) skipped 11
Filings about a different issuer 0
Unreadable filings 0
Joint filings 16
Sales on a Rule 10b5-1 plan 46
Sales straight out of an exercise 68
Sales at will 387
Transactions with no price 0
Shares from compensation/vesting 63,608,485
Sales filed before the plan box existed 354
History held since 8 Dec 2017