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RHYTHM PHARMACEUTICALS, INC.

RYTM Net buying
CIK 0001649904 #1081 in the set updated 17 Sep 2026
Bought (120 mo)
$106.96M
out of their own pocket, the only kind of buying there is
Sold (120 mo)
$178.55M
$6.80M on a plan · $93.23M straight out of an exercise
Sold at will
$78.52M
113 of 310 sales
Net
−$71.59M
+$28.44M against sales at will

By person

38 insiders · 351 transactions
31.1×

David P. Meeker holds 31.1 times base salary in stock. $25.17M of shares against $807.69K in salary for 2025.

Salary from the company's own proxy. The shares are what David P. Meeker last reported holding, valued at $105.19, the price Common Stock was last bought or sold at on the open market here, on 14 Sep 2026.

Insider
Role
Bought
Sold
Net
Holding
Of company
Worth
Change
Foley Todd
Director
$1.70M (1)
$50.56M (47)
−$48.86M
909,258
1.32%
$95.64M
+122.9%
Smith Hunter C
Chief Financial Officer
—
$19.38M (51) scheduled
−$19.38M
114,024
0.1656%
$11.99M
—
Lee Jennifer Kayden
EVP, Head of North America
—
$16.91M (36) scheduled
−$16.91M
0
0.0000%
$0.00
−100.0%
Shulman Joseph
Chief Technical Officer
—
$15.73M (41) scheduled
−$15.73M
15,915
0.0231%
$1.67M
—
BAKER BROS. ADVISORS LP entity
Former 10% owner
$15.05M (2)
—
+$15.05M
1,878,242
2.73%
$197.57M
—
RA CAPITAL MANAGEMENT, L.P. entity
Former 10% Owner
—
$13.40M (12)
−$13.40M
4,360,860
6.33%
$458.72M
−10.7%
Mazabraud Yann
EVP, Head of International
—
$12.84M (17) scheduled
−$12.84M
55,655
0.0808%
$5.85M
+168.4%
Cramer Pamela J.
Chief Human Resources Officer
—
$10.96M (32) scheduled
−$10.96M
29,376
0.0427%
$3.09M
+1,080%
Meeker David P
President and CEO
$626.71K (2)
$10.77M (11) scheduled
−$10.15M
239,258
0.3475%
$25.17M
+752.3%
BARRETT M JAMES
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
BARRIS PETER J
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
BASKETT FOREST
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
KERINS PATRICK J
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
MOTT DAVID M
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
NEW ENTERPRISE ASSOCIATES 13 LP entity
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
SANDELL SCOTT D
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
Viswanathan Ravi
10% owner
$9.35M (1)
—
+$9.35M
4,909,956
7.13%
$516.48M
+16,613%
Flynn James E
10% owner
$6.04M (2)
—
+$6.04M
468,505
0.6805%
$49.28M
—
TETRAULT LYNN A.
Director
—
$5.40M (8) scheduled
−$5.40M
11,712
0.0170%
$1.23M
—
GOOD JENNIFER L
Director
—
$4.27M (3) scheduled
−$4.27M
11,712
0.0170%
$1.23M
—
MCGIRR DAVID W J
Director
—
$4.27M (2) scheduled
−$4.27M
11,712
0.0170%
$1.23M
—
Van der Ploeg Leonardus H.T.
Chief Scientific Officer
—
$2.73M (11) scheduled
−$2.73M
42,339
0.0615%
$4.45M
−34.2%
Gottesdiener Keith Michael
CEO & President
—
$2.48M (15)
−$2.48M
558,250
0.8108%
$58.72M
−0.3%
MPM BIOVENTURES V, L.P.
10% owner
$1.70M (1)
—
+$1.70M
2,696,392
3.92%
$283.63M
+9,078%
German Christopher Paul
Corporate Controller & CAO
—
$1.59M (9) scheduled
−$1.59M
0
0.0000%
$0.00
−100.0%
Desikan Nithya
Chief Commercial Officer
—
$1.55M (2) scheduled
−$1.55M
43,602
0.0633%
$4.59M
—
ORBIMED ADVISORS LLC entity
10% owner
$6.04M (1)
$4.66M (4)
+$1.37M
2,750,079
3.99%
$289.28M
—
Garfield Alastair
Chief Scientific Officer
—
$998.19K (6) scheduled
−$998.19K
2,295
0.0033%
$241.41K
—
PFIZER INC entity
10% owner
$680.00K (1)
—
+$680.00K
1,427,639
2.07%
$150.17M
—
Ipsen, S.A.
10% owner
$340.00K (1)
—
+$340.00K
833,099
1.21%
$87.63M
+39.0%
Roberts William T.
Chief Accounting Officer
—
$53.87K (3) scheduled
−$53.87K
7,872
0.0114%
$828.06K
+128.0%
THIRD ROCK VENTURES LP entity
10% owner
—
—
—
2,981,437
4.33%
$313.62M
+16,814%
Hadley Harbor Master Investors (Cayman) L.P.
10% owner
—
—
—
545,256
0.7919%
$57.36M
—
Mathers Edward T
Director
—
—
—
21,168
0.0307%
$2.23M
—
Arbuckle Stuart A
Director
—
—
—
11,712
0.0170%
$1.23M
—
JEAN CHRISTOPHE
Director
—
—
—
11,712
0.0170%
$1.23M
—
Bedrosian Camille L
Director
—
—
—
7,000
0.0102%
$736.33K
—
Exter Neil
Director
—
—
—
0
0.0000%
$0.00
—

Individual transactions

54
Insider
Date
Role
Action
Shares
Price
Amount
German Christopher Paul
21 Mar 2025
Corporate Controller & CAO
Sell
344
$54.23
$18.66K
German Christopher Paul
19 Feb 2025
Corporate Controller & CAO
Sell
635
$57.22
$36.33K
Cramer Pamela J.
4 Feb 2025
Chief Human Resources Officer
Sell
902
$59.43
$53.61K
Lee Jennifer Kayden
4 Feb 2025
EVP, Head of North America
Sell
1,447
$59.43
$86.00K
Meeker David P
4 Feb 2025
President and CEO
Sell
4,278
$59.43
$254.24K
Shulman Joseph
4 Feb 2025
Chief Technical Officer
Sell
1,281
$59.43
$76.13K
Smith Hunter C
4 Feb 2025
Chief Financial Officer
Sell
1,678
$59.43
$99.72K
German Christopher Paul
2 Apr 2024
Corporate Controller & CAO
Sell
368
$41.76
$15.37K
Shulman Joseph
21 Mar 2024
Chief Technical Officer
Sell
18,235
$40.34
$735.60K
Lee Jennifer Kayden
20 Mar 2024
EVP, Head of North America
Sell
9,066
$39.33
$356.57K
Lee Jennifer Kayden
20 Mar 2024
EVP, Head of North America
Sell
9,169
$38.22
$350.44K
Cramer Pamela J.
19 Mar 2024
Chief Human Resources Officer
Sell
15,515
$39.22
$608.50K
Lee Jennifer Kayden
19 Mar 2024
EVP, Head of North America
Sell
15,515
$39.22
$608.50K
Mazabraud Yann
19 Mar 2024
EVP, Head of International
Sell
16,000
$39.22
$627.52K
Meeker David P
19 Mar 2024
President and CEO
Sell
45,494
$39.22
$1.78M
Shulman Joseph
19 Mar 2024
Chief Technical Officer
Sell
15,515
$39.22
$608.50K
Smith Hunter C
19 Mar 2024
Chief Financial Officer
Sell
15,515
$39.22
$608.50K
Lee Jennifer Kayden
13 Feb 2024
EVP, Head of North America
Sell
615
$49.83
$30.65K
Mazabraud Yann
13 Feb 2024
EVP, Head of International
Sell
957
$49.84
$47.70K
Smith Hunter C
13 Feb 2024
Chief Financial Officer
Sell
709
$49.82
$35.32K
Cramer Pamela J.
12 Feb 2024
Chief Human Resources Officer
Sell
696
$51.38
$35.76K
Lee Jennifer Kayden
12 Feb 2024
EVP, Head of North America
Sell
1,023
$51.38
$52.56K
Mazabraud Yann
12 Feb 2024
EVP, Head of International
Sell
1,594
$51.38
$81.90K
Smith Hunter C
12 Feb 2024
Chief Financial Officer
Sell
1,209
$51.38
$62.12K
Smith Hunter C
14 Feb 2023
Chief Financial Officer
Sell
702
$26.87
$18.86K
Lee Jennifer Kayden
14 Feb 2023
EVP, Head of North America
Sell
635
$26.87
$17.06K
Shulman Joseph
14 Feb 2023
Chief Technical Officer
Sell
554
$26.87
$14.89K
Mazabraud Yann
14 Feb 2023
EVP, Head of International
Sell
1,177
$27.03
$31.81K
Cramer Pamela J.
27 Jul 2022
Chief Human Resources Officer
Sell
901
$11.68
$10.52K
Smith Hunter C
1 Jul 2022
Chief Financial Officer
Sell
7,547
$4.08
$30.79K
Lee Jennifer Kayden
15 Feb 2022
EVP, Head of North America
Sell
722
$6.10
$4.40K
Mazabraud Yann
15 Feb 2022
EVP, Head of International
Sell
934
$6.10
$5.70K
Smith Hunter C
15 Feb 2022
Chief Financial Officer
Sell
833
$6.10
$5.08K
Shulman Joseph
15 Feb 2022
Chief Technical Officer
Sell
557
$6.10
$3.40K
Foley Todd
15 Mar 2021
Director
Sell indirect
1,000,000
$25.10
$25.10M
RA CAPITAL MANAGEMENT, L.P.
3 Dec 2020
Former 10% Owner
Sell indirect
44,738
$28.75
$1.29M
RA CAPITAL MANAGEMENT, L.P.
3 Dec 2020
Former 10% Owner
Sell indirect
139,308
$28.95
$4.03M
RA CAPITAL MANAGEMENT, L.P.
3 Dec 2020
Former 10% Owner
Sell indirect
12,976
$29.11
$377.73K
RA CAPITAL MANAGEMENT, L.P.
3 Dec 2020
Former 10% Owner
Sell indirect
10,582
$31.23
$330.48K
RA CAPITAL MANAGEMENT, L.P.
2 Dec 2020
Former 10% Owner
Sell indirect
12,060
$32.23
$388.69K
RA CAPITAL MANAGEMENT, L.P.
2 Dec 2020
Former 10% Owner
Sell indirect
18,879
$32.50
$613.57K
RA CAPITAL MANAGEMENT, L.P.
2 Jul 2020
10% owner
Sell indirect
44,153
$22.04
$972.97K
RA CAPITAL MANAGEMENT, L.P.
1 Jul 2020
10% owner
Sell indirect
25,527
$21.87
$558.31K
RA CAPITAL MANAGEMENT, L.P.
30 Jun 2020
10% owner
Sell indirect
61,901
$22.15
$1.37M
RA CAPITAL MANAGEMENT, L.P.
29 Jun 2020
10% owner
Sell indirect
52,049
$22.19
$1.15M
RA CAPITAL MANAGEMENT, L.P.
26 Jun 2020
10% owner
Sell indirect
86,706
$23.31
$2.02M
Foley Todd
26 Jun 2020
Director
Sell indirect
300
$25.04
$7.51K
Foley Todd
25 Jun 2020
Director
Sell indirect
17,947
$25.41
$456.03K
RA CAPITAL MANAGEMENT, L.P.
25 Jun 2020
10% owner
Sell indirect
11,568
$25.05
$289.77K
Foley Todd
24 Jun 2020
Director
Sell indirect
97,388
$25.34
$2.47M
Foley Todd
5 Jun 2020
Director
Sell indirect
1,896
$20.00
$37.92K
Foley Todd
3 Jun 2020
Director
Sell indirect
18,245
$20.27
$369.83K
Foley Todd
2 Jun 2020
Director
Sell indirect
15,578
$20.23
$315.14K
Foley Todd
1 Jun 2020
Director
Sell indirect
10,535
$20.08
$211.54K
Showing 250 of 351 transactions. The figures above use every one of them.

What was left out

Form 4 filings counted 376
Amendments (4/A) skipped 8
Filings about a different issuer 0
Unreadable filings 0
Joint filings 12
Sales on a Rule 10b5-1 plan 58
Sales straight out of an exercise 139
Sales at will 113
Transactions with no price 0
Shares from compensation/vesting 53,596,983
Sales filed before the plan box existed 89
History held since 6 Oct 2017