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IONIS PHARMACEUTICALS INC

IONS Net selling
CIK 0000874015 #948 in the set updated 17 Sep 2026
Bought (12 mo)
$1.06M
out of their own pocket, the only kind of buying there is
Sold (12 mo)
$155.14M
$17.39M on a plan · $118.69M straight out of an exercise
Sold at will
$19.06M
25 of 143 sales
Net
−$154.08M
−$18.00M against sales at will

By person

21 insiders · 146 transactions
11.9×

Brett P. Monia holds 11.9 times base salary in stock. $12.53M of shares against $1.05M in salary for 2025.

Salary from the company's own proxy. The shares are what Brett P. Monia last reported holding, valued at $51.60, the price Common Stock was last bought or sold at on the open market here, on 31 Jul 2026.

Insider
Role
Bought
Sold
Net
Holding
Of company
Worth
Change
Monia Brett P
Chief Executive Officer
—
$30.35M (14) scheduled
−$30.35M
242,760
0.1461%
$12.53M
+39.5%
HOUGEN ELIZABETH L
EVP, Finance & CFO
—
$21.12M (6) scheduled
−$21.12M
82,660
0.0497%
$4.27M
−11.0%
BENNETT C FRANK
EVP, Chief Scientific Officer
—
$16.71M (10) scheduled
−$16.71M
60,128
0.0362%
$3.10M
−28.9%
Geary Richard S
EVP, Chief Development Officer
—
$13.23M (10) scheduled
−$13.23M
59,657
0.0359%
$3.08M
−29.7%
O'NEIL PATRICK R.
EVP CLO & General Counsel
—
$9.17M (10) scheduled
−$9.17M
59,205
0.0356%
$3.05M
+21.1%
Devers Shannon L.
EVP, Chief Human Resources Ofc
—
$8.66M (14) scheduled
−$8.66M
16,348
0.0098%
$843.56K
+106.7%
Swayze Eric
EVP Research
—
$7.51M (12) scheduled
−$7.51M
22,077
0.0133%
$1.14M
−36.9%
LOSCALZO JOSEPH
Director
—
$7.09M (5) scheduled
−$7.09M
36,330
0.0219%
$1.87M
−20.6%
KLEIN JOSEPH III
Director
—
$6.00M (12) scheduled
−$6.00M
11,014
0.0066%
$568.32K
−32.6%
WENDER JOSEPH H
Director
—
$5.44M (7) scheduled
−$5.44M
52,035
0.0313%
$2.69M
−67.6%
Diaz Allene M.
Director
—
$5.22M (4) scheduled
−$5.22M
3,811
0.0023%
$196.65K
−75.8%
Kordasiewicz Holly B.
EVP, Chief Development Officer
—
$4.81M (4) scheduled
−$4.81M
22,096
0.0133%
$1.14M
+42.7%
Schneider Eugene
EVP, Chf Clinical Develop Ofcr
—
$3.74M (4) scheduled
−$3.74M
77,114
0.0464%
$3.98M
+26.7%
Baroldi Joseph
EVP, Chief Business Officer
—
$3.70M (13) scheduled
−$3.70M
49,578
0.0298%
$2.56M
+129.6%
Birchler Brian
EVP, Corp and Development Ops
—
$3.56M (6) scheduled
−$3.56M
102,883
0.0619%
$5.31M
+26.2%
Jenne Kyle
EVP, Chf GL Pdt Str Ofcr
—
$3.33M (4) scheduled
−$3.33M
23,713
0.0143%
$1.22M
+1,092%
HERMAN JOAN E
Director
—
$3.17M (2) scheduled
−$3.17M
51,306
0.0309%
$2.65M
+22.1%
BERTHELSEN SPENCER R
Director
—
$1.19M (2) scheduled
−$1.19M
161,233
0.0970%
$8.32M
+6.1%
PARSHALL B LYNNE
Director
—
$1.15M (4) scheduled
−$1.15M
51,344
0.0309%
$2.65M
−41.2%
Hayden Michael R
Director
$1.06M (2)
—
+$1.06M
78,298
0.0471%
$4.04M
+128.8%
YANG MICHAEL J.
Director
—
—
—
7,940
0.0048%
$409.70K
—

Individual transactions

146
Insider
Date
Role
Action
Shares
Price
Amount
Hayden Michael R
31 Jul 2026
Director
Buy indirect
5,000
$51.60
$258.00K
Hayden Michael R
30 Jul 2026
Director
Buy indirect
15,000
$53.38
$800.70K
Kordasiewicz Holly B.
7 Jul 2026
EVP, Chief Development Officer
Sold on a plan
362
$84.30
$30.52K
Diaz Allene M.
7 Jul 2026
Director
Sold after exercise
10,111
$85.42
$863.64K
BENNETT C FRANK
7 Jul 2026
EVP, Chief Scientific Officer
Sold on a plan indirect
15,000
$85.46
$1.28M
BENNETT C FRANK
7 Jul 2026
EVP, Chief Scientific Officer
Sold on a plan
5,536
$83.58
$462.69K
KLEIN JOSEPH III
1 Jul 2026
Director
Sold after exercise
11,419
$79.04
$902.55K
KLEIN JOSEPH III
1 Jul 2026
Director
Sold after exercise
99
$79.45
$7.87K
Monia Brett P
26 Jun 2026
Chief Executive Officer
Sold after exercise
50,000
$80.59
$4.03M
Schneider Eugene
26 Jun 2026
EVP, Chf Clinical Develop Ofcr
Sold after exercise
26,000
$81.05
$2.11M
O'NEIL PATRICK R.
26 Jun 2026
EVP CLO & General Counsel
Sold on a plan
3,069
$80.00
$245.52K
Baroldi Joseph
26 Jun 2026
EVP, Chief Business Officer
Sold after exercise indirect
5,635
$80.16
$451.70K
Swayze Eric
25 Jun 2026
EVP Research
Sold on a plan
10,602
$79.18
$839.49K
Monia Brett P
25 Jun 2026
Chief Executive Officer
Sold after exercise
21,072
$78.49
$1.65M
Monia Brett P
24 Jun 2026
Chief Executive Officer
Sold after exercise
14,565
$78.41
$1.14M
BERTHELSEN SPENCER R
15 Jun 2026
Director
Sold after exercise
8,000
$73.49
$587.92K
Kordasiewicz Holly B.
12 Jun 2026
EVP, Chief Development Officer
Sold after exercise
19,842
$74.05
$1.47M
Kordasiewicz Holly B.
12 Jun 2026
EVP, Chief Development Officer
Sold after exercise
41,004
$73.09
$3.00M
BERTHELSEN SPENCER R
1 Jun 2026
Director
Sold after exercise
8,000
$75.67
$605.36K
Monia Brett P
14 May 2026
Chief Executive Officer
Sold after exercise
3,220
$78.68
$253.35K
Monia Brett P
13 May 2026
Chief Executive Officer
Sold after exercise
1,316
$78.01
$102.67K
LOSCALZO JOSEPH
4 May 2026
Director
Sold after exercise
17,781
$75.58
$1.34M
LOSCALZO JOSEPH
4 May 2026
Director
Sold after exercise
59,508
$74.90
$4.46M
KLEIN JOSEPH III
1 May 2026
Director
Sold after exercise
1,431
$74.45
$106.53K
KLEIN JOSEPH III
1 May 2026
Director
Sold after exercise
8,680
$73.35
$636.70K
Baroldi Joseph
28 Apr 2026
EVP, Chief Business Officer
Sold on a plan
1,626
$71.79
$116.73K
Baroldi Joseph
16 Apr 2026
EVP, Chief Business Officer
Sell
5,619
$74.56
$418.95K
Birchler Brian
16 Apr 2026
EVP, Corp and Development Ops
Sell
973
$75.04
$73.02K
Jenne Kyle
16 Apr 2026
EVP, Chf GL Pdt Str Ofcr
Sell
4,902
$75.17
$368.49K
PARSHALL B LYNNE
15 Apr 2026
Director
Sold on a plan
534
$76.97
$41.10K
PARSHALL B LYNNE
15 Apr 2026
Director
Sold on a plan
4,466
$76.19
$340.26K
Devers Shannon L.
2 Apr 2026
EVP, Chief Human Resources Ofc
Sold on a plan
6,193
$74.05
$458.61K
KLEIN JOSEPH III
1 Apr 2026
Director
Sold after exercise
2,216
$75.95
$168.31K
KLEIN JOSEPH III
1 Apr 2026
Director
Sold after exercise
20,105
$75.50
$1.52M
Schneider Eugene
19 Mar 2026
EVP, Chf Clinical Develop Ofcr
Sold on a plan
5,812
$70.97
$412.49K
HOUGEN ELIZABETH L
17 Mar 2026
EVP, Finance & CFO
Sold on a plan
10,172
$73.21
$744.66K
HOUGEN ELIZABETH L
16 Mar 2026
EVP, Finance & CFO
Sold after exercise
9,440
$72.77
$686.90K
HOUGEN ELIZABETH L
16 Mar 2026
EVP, Finance & CFO
Sold after exercise
205,608
$72.38
$14.88M
Jenne Kyle
10 Mar 2026
EVP, Chf GL Pdt Str Ofcr
Sold after exercise
16,086
$76.30
$1.23M
Jenne Kyle
10 Mar 2026
EVP, Chf GL Pdt Str Ofcr
Sold after exercise
21,191
$75.50
$1.60M
Monia Brett P
10 Mar 2026
Chief Executive Officer
Sold after exercise
17,591
$76.34
$1.34M
Monia Brett P
10 Mar 2026
Chief Executive Officer
Sold after exercise
16,512
$75.47
$1.25M
Monia Brett P
9 Mar 2026
Chief Executive Officer
Sold after exercise
1,684
$75.58
$127.28K
Monia Brett P
9 Mar 2026
Chief Executive Officer
Sold after exercise
117,604
$75.26
$8.85M
Monia Brett P
9 Mar 2026
Chief Executive Officer
Sold after exercise
7,382
$74.11
$547.09K
O'NEIL PATRICK R.
9 Mar 2026
EVP CLO & General Counsel
Sold on a plan
10,148
$75.25
$763.66K
Baroldi Joseph
4 Mar 2026
EVP, Chief Business Officer
Sold after exercise indirect
201
$80.00
$16.08K
Baroldi Joseph
4 Mar 2026
EVP, Chief Business Officer
Sold after exercise indirect
238
$80.00
$19.04K
LOSCALZO JOSEPH
4 Mar 2026
Director
Sold after exercise
200
$80.00
$16.00K
Baroldi Joseph
3 Mar 2026
EVP, Chief Business Officer
Sold after exercise indirect
36
$81.01
$2.92K
Baroldi Joseph
3 Mar 2026
EVP, Chief Business Officer
Sold after exercise indirect
2,088
$80.41
$167.89K
Baroldi Joseph
3 Mar 2026
EVP, Chief Business Officer
Sold after exercise
4,096
$79.36
$325.06K
BENNETT C FRANK
3 Mar 2026
EVP, Chief Scientific Officer
Sold after exercise
802
$80.76
$64.77K
BENNETT C FRANK
3 Mar 2026
EVP, Chief Scientific Officer
Sold after exercise
12,687
$79.88
$1.01M
BENNETT C FRANK
3 Mar 2026
EVP, Chief Scientific Officer
Sold after exercise
71,600
$79.10
$5.66M
Devers Shannon L.
3 Mar 2026
EVP, Chief Human Resources Ofc
Sold after exercise
755
$80.84
$61.03K
Devers Shannon L.
3 Mar 2026
EVP, Chief Human Resources Ofc
Sold after exercise
5,030
$80.00
$402.39K
Devers Shannon L.
3 Mar 2026
EVP, Chief Human Resources Ofc
Sold after exercise
14,321
$79.12
$1.13M
Diaz Allene M.
3 Mar 2026
Director
Sold after exercise
1,005
$80.80
$81.20K
Diaz Allene M.
3 Mar 2026
Director
Sold after exercise
14,608
$79.88
$1.17M
Diaz Allene M.
3 Mar 2026
Director
Sold after exercise
39,265
$79.11
$3.11M
KLEIN JOSEPH III
3 Mar 2026
Director
Sold after exercise
1,012
$80.82
$81.79K
KLEIN JOSEPH III
3 Mar 2026
Director
Sold after exercise
6,794
$80.00
$543.49K
KLEIN JOSEPH III
3 Mar 2026
Director
Sold after exercise
13,526
$79.17
$1.07M
LOSCALZO JOSEPH
3 Mar 2026
Director
Sold after exercise
832
$80.33
$66.83K
Swayze Eric
13 Feb 2026
EVP Research
Sold on a plan
6,207
$82.07
$509.40K
Swayze Eric
13 Feb 2026
EVP Research
Sold on a plan
9,435
$81.56
$769.51K
PARSHALL B LYNNE
11 Feb 2026
Director
Sold on a plan
5,000
$82.72
$413.59K
Monia Brett P
6 Feb 2026
Chief Executive Officer
Sold on a plan
29,430
$85.79
$2.52M
BENNETT C FRANK
2 Feb 2026
EVP, Chief Scientific Officer
Sold after exercise
16,463
$83.03
$1.37M
BENNETT C FRANK
2 Feb 2026
EVP, Chief Scientific Officer
Sold after exercise
48,626
$83.03
$4.04M
BENNETT C FRANK
2 Feb 2026
EVP, Chief Scientific Officer
Sold after exercise
20,000
$82.60
$1.65M
Baroldi Joseph
30 Jan 2026
EVP, Chief Business Officer
Sell
5,296
$82.96
$439.36K
BENNETT C FRANK
30 Jan 2026
EVP, Chief Scientific Officer
Sell
5,885
$82.95
$488.14K
Birchler Brian
30 Jan 2026
EVP, Corp and Development Ops
Sell
6,179
$83.03
$513.05K
HOUGEN ELIZABETH L
30 Jan 2026
EVP, Finance & CFO
Sell
6,988
$83.24
$581.70K
Monia Brett P
30 Jan 2026
Chief Executive Officer
Sell
62,970
$82.72
$5.21M
O'NEIL PATRICK R.
30 Jan 2026
EVP CLO & General Counsel
Sell
6,179
$83.53
$516.15K
Schneider Eugene
30 Jan 2026
EVP, Chf Clinical Develop Ofcr
Sell
6,179
$83.45
$515.63K
Swayze Eric
30 Jan 2026
EVP Research
Sell
6,179
$82.93
$512.45K
Devers Shannon L.
22 Jan 2026
EVP, Chief Human Resources Ofc
Sold on a plan
3,977
$81.34
$323.49K
Baroldi Joseph
16 Jan 2026
EVP, Chief Business Officer
Sell indirect
1,149
$75.78
$87.07K
Baroldi Joseph
16 Jan 2026
EVP, Chief Business Officer
Sell
6,907
$75.75
$523.21K
BENNETT C FRANK
16 Jan 2026
EVP, Chief Scientific Officer
Sell
8,977
$75.15
$674.62K
Birchler Brian
16 Jan 2026
EVP, Corp and Development Ops
Sell
8,480
$75.11
$636.93K
Devers Shannon L.
16 Jan 2026
EVP, Chief Human Resources Ofc
Sell
8,353
$75.95
$634.41K
HOUGEN ELIZABETH L
16 Jan 2026
EVP, Finance & CFO
Sell
12,922
$75.22
$971.99K
Jenne Kyle
16 Jan 2026
EVP, Chf GL Pdt Str Ofcr
Sell
1,823
$75.96
$138.48K
Kordasiewicz Holly B.
16 Jan 2026
EVP, Chief Development Officer
Sell
4,141
$75.66
$313.31K
Monia Brett P
16 Jan 2026
Chief Executive Officer
Sell
44,034
$74.82
$3.29M
O'NEIL PATRICK R.
16 Jan 2026
EVP CLO & General Counsel
Sell
9,191
$75.84
$697.05K
Schneider Eugene
16 Jan 2026
EVP, Chf Clinical Develop Ofcr
Sell
9,302
$75.59
$703.14K
Swayze Eric
16 Jan 2026
EVP Research
Sell indirect
49
$75.97
$3.72K
Swayze Eric
16 Jan 2026
EVP Research
Sell
9,884
$75.34
$744.66K
Devers Shannon L.
7 Jan 2026
EVP, Chief Human Resources Ofc
Sold after exercise
9,264
$84.62
$783.92K
Devers Shannon L.
7 Jan 2026
EVP, Chief Human Resources Ofc
Sold after exercise
3,829
$84.62
$324.01K
Devers Shannon L.
7 Jan 2026
EVP, Chief Human Resources Ofc
Sold after exercise
3,460
$84.62
$292.79K
Devers Shannon L.
7 Jan 2026
EVP, Chief Human Resources Ofc
Sold after exercise
2,101
$85.36
$179.34K
Devers Shannon L.
7 Jan 2026
EVP, Chief Human Resources Ofc
Sold after exercise
25,545
$85.36
$2.18M
Swayze Eric
2 Jan 2026
EVP Research
Sold after exercise
18,338
$79.27
$1.45M
Swayze Eric
2 Jan 2026
EVP Research
Sold after exercise
5,125
$78.57
$402.67K
WENDER JOSEPH H
1 Dec 2025
Director
Sold on a plan indirect
7,429
$81.23
$603.49K
WENDER JOSEPH H
1 Dec 2025
Director
Sold on a plan indirect
20,571
$80.67
$1.66M
Devers Shannon L.
25 Nov 2025
EVP, Chief Human Resources Ofc
Sold after exercise
16,777
$80.91
$1.36M
KLEIN JOSEPH III
25 Nov 2025
Director
Sold after exercise indirect
4,000
$80.00
$320.00K
KLEIN JOSEPH III
25 Nov 2025
Director
Sold after exercise indirect
4,000
$80.00
$320.00K
KLEIN JOSEPH III
25 Nov 2025
Director
Sold after exercise indirect
4,000
$80.00
$320.00K
HERMAN JOAN E
19 Nov 2025
Director
Sold after exercise
32,000
$72.13
$2.31M
HERMAN JOAN E
19 Nov 2025
Director
Sold after exercise
12,000
$72.13
$865.59K
WENDER JOSEPH H
18 Nov 2025
Director
Exercised, kept
16,000
$24.42
$390.72K
Geary Richard S
6 Nov 2025
EVP, Chief Development Officer
Sold after exercise
18,300
$75.42
$1.38M
Geary Richard S
6 Nov 2025
EVP, Chief Development Officer
Sold after exercise
14,738
$76.10
$1.12M
Birchler Brian
6 Nov 2025
EVP, Corp and Development Ops
Sold on a plan
8,000
$76.17
$609.38K
Geary Richard S
5 Nov 2025
EVP, Chief Development Officer
Sold after exercise
801
$75.01
$60.08K
Geary Richard S
5 Nov 2025
EVP, Chief Development Officer
Sold after exercise
800
$75.01
$60.01K
Geary Richard S
3 Nov 2025
EVP, Chief Development Officer
Sold after exercise
905
$75.05
$67.92K
Geary Richard S
3 Nov 2025
EVP, Chief Development Officer
Sold after exercise
775
$75.05
$58.17K
Geary Richard S
31 Oct 2025
EVP, Chief Development Officer
Sold after exercise
20,000
$75.11
$1.50M
Geary Richard S
31 Oct 2025
EVP, Chief Development Officer
Sold after exercise
34,664
$75.11
$2.60M
Geary Richard S
31 Oct 2025
EVP, Chief Development Officer
Sold after exercise
34,585
$75.11
$2.60M
LOSCALZO JOSEPH
31 Oct 2025
Director
Sold after exercise
16,000
$75.10
$1.20M
WENDER JOSEPH H
31 Oct 2025
Director
Sold on a plan indirect
11,200
$75.16
$841.78K
WENDER JOSEPH H
30 Oct 2025
Director
Sold on a plan indirect
5,975
$73.85
$441.25K
WENDER JOSEPH H
30 Oct 2025
Director
Sold on a plan indirect
8,341
$73.16
$610.23K
WENDER JOSEPH H
30 Oct 2025
Director
Sold on a plan indirect
2,484
$72.19
$179.32K
Devers Shannon L.
16 Oct 2025
EVP, Chief Human Resources Ofc
Sold on a plan
1,263
$73.62
$92.98K
Swayze Eric
16 Oct 2025
EVP Research
Sell indirect
53
$73.62
$3.90K
Birchler Brian
15 Oct 2025
EVP, Corp and Development Ops
Sold after exercise
12,425
$72.23
$897.40K
Devers Shannon L.
15 Oct 2025
EVP, Chief Human Resources Ofc
Sold after exercise
6,000
$72.94
$437.65K
PARSHALL B LYNNE
15 Oct 2025
Director
Sold on a plan
5,000
$71.74
$358.72K
Birchler Brian
14 Oct 2025
EVP, Corp and Development Ops
Sold after exercise
11,475
$72.03
$826.59K
Baroldi Joseph
6 Oct 2025
EVP, Chief Business Officer
Sold on a plan
1,625
$69.37
$112.73K
Monia Brett P
6 Oct 2025
Chief Executive Officer
Sold on a plan
437
$69.26
$30.27K
O'NEIL PATRICK R.
6 Oct 2025
EVP CLO & General Counsel
Sold after exercise
3,241
$69.27
$224.49K
O'NEIL PATRICK R.
6 Oct 2025
EVP CLO & General Counsel
Sold after exercise
10,200
$69.89
$712.85K
Swayze Eric
6 Oct 2025
EVP Research
Sold on a plan
6,849
$69.02
$472.72K
Baroldi Joseph
2 Oct 2025
EVP, Chief Business Officer
Sold after exercise
15,000
$68.01
$1.02M
O'NEIL PATRICK R.
2 Oct 2025
EVP CLO & General Counsel
Sold after exercise
34,461
$67.69
$2.33M
O'NEIL PATRICK R.
2 Oct 2025
EVP CLO & General Counsel
Sold after exercise
30,203
$67.69
$2.04M
Swayze Eric
2 Oct 2025
EVP Research
Sold after exercise
12,972
$66.23
$859.08K
Swayze Eric
1 Oct 2025
EVP Research
Sold after exercise
14,142
$66.09
$934.66K
WENDER JOSEPH H
1 Oct 2025
Director
Sold on a plan indirect
16,800
$65.50
$1.10M
HOUGEN ELIZABETH L
30 Sep 2025
EVP, Finance & CFO
Sold after exercise
49,800
$65.26
$3.25M
Geary Richard S
30 Sep 2025
EVP, Chief Development Officer
Sold after exercise
57,900
$65.24
$3.78M
O'NEIL PATRICK R.
30 Sep 2025
EVP CLO & General Counsel
Sold after exercise
14,827
$64.68
$958.98K
O'NEIL PATRICK R.
29 Sep 2025
EVP CLO & General Counsel
Sold after exercise
10,473
$64.54
$675.95K

What was left out

Form 4 filings counted 117
Amendments (4/A) skipped 3
Filings about a different issuer 0
Unreadable filings 0
Joint filings 0
Sales on a Rule 10b5-1 plan 30
Sales straight out of an exercise 88
Sales at will 25
Transactions with no price 0
Shares from compensation/vesting 2,000,192
History held since 6 Sep 2016