Insider
Date
Role
Action
Shares
Price
Amount
Luly Jay R.
5 Dec 2025
President and CEO
Sell
4,743
$14.23
$67.49K
Or Yat Sun
5 Dec 2025
Chief Scientific Officer
Sell
2,390
$14.23
$34.01K
Kieffer Tara Lynn
5 Dec 2025
Chief Product Strategy Officer
Sell
2,106
$14.23
$29.97K
Luu Brendan
5 Dec 2025
Chief Business Officer
Sell
1,394
$14.23
$19.84K
Rottinghaus Scott T.
5 Dec 2025
Chief Medical Officer
Sell
798
$14.23
$11.36K
Trout Harry R. III
5 Dec 2025
See Remarks
Sell
542
$14.23
$7.71K
Capps Kathleen S.
5 Dec 2025
See Remarks
Sell
323
$14.23
$4.60K
Trout Harry R. III
2 Dec 2025
See Remarks
Sell
380
$13.96
$5.30K
Capps Kathleen S.
2 Dec 2025
See Remarks
Sell
207
$13.96
$2.89K
Luly Jay R.
12 Feb 2025
President and CEO
Buy
45,000
$5.69
$256.05K
Luly Jay R.
6 Dec 2024
President and CEO
Sold on a plan
5,142
$8.06
$41.44K
MELLETT PAUL J
6 Dec 2024
Chief Fin. & Admin Officer
Sold on a plan
2,591
$8.06
$20.88K
Or Yat Sun
6 Dec 2024
Chief Scientific Officer
Sold on a plan
2,591
$8.06
$20.88K
Rottinghaus Scott T.
6 Dec 2024
Chief Medical Officer
Sold on a plan
866
$8.06
$6.98K
Luu Brendan
6 Dec 2024
Chief Business Officer
Sold on a plan
2,283
$8.06
$18.40K
Kieffer Tara Lynn
6 Dec 2024
Chief Product Strategy Officer
Sold on a plan
2,283
$8.06
$18.40K
Rottinghaus Scott T.
15 Jul 2024
Chief Medical Officer
Sold after exercise
5,375
$17.08
$91.81K
Rottinghaus Scott T.
12 Jul 2024
Chief Medical Officer
Sold on a plan
2,271
$15.04
$34.16K
Rottinghaus Scott T.
11 Jul 2024
Chief Medical Officer
Sold on a plan
4,299
$15.07
$64.79K
Kieffer Tara Lynn
17 Jun 2024
Chief Product Strategy Officer
Sold on a plan
7,266
$12.33
$89.59K
Gardiner Nathaniel S.
26 Feb 2024
Chief Legal Officer
Exercised, kept
5,187
$8.99
$46.63K
Vance Terry
13 Dec 2023
Director
Sell
15,295
$9.12
$139.49K
Luly Jay R.
5 Dec 2023
President and CEO
Sell
7,230
$9.63
$69.62K
MELLETT PAUL J
5 Dec 2023
Sr. VP, Finance & Admin. & CFO
Sell
2,412
$9.63
$23.23K
Or Yat Sun
5 Dec 2023
Sr. VP, R&D & CSO
Sell
2,412
$9.63
$23.23K
Rottinghaus Scott T.
5 Dec 2023
Sr. VP & CMO
Sell
534
$9.63
$5.14K
Gardiner Nathaniel S.
5 Dec 2023
Sr. VP & General Counsel
Sell
2,412
$9.63
$23.23K
Kieffer Tara Lynn
5 Dec 2023
Sr. VP, New Prod. Strat. & Dev
Sell
2,125
$9.63
$20.46K
Luu Brendan
5 Dec 2023
Sr. VP, Business Dev.
Sell
2,125
$9.63
$20.46K
Gardiner Nathaniel S.
18 Apr 2023
Sr. VP & General Counsel
Exercised, kept
6,667
$30.00
$200.01K
Vance Terry
16 Mar 2023
Director
Exercised, kept
5,800
$14.00
$81.20K
Or Yat Sun
15 Mar 2023
Sr. VP & CSO
Sold after exercise
13,656
$44.46
$607.15K
Or Yat Sun
15 Mar 2023
Sr. VP & CSO
Sold after exercise
269
$43.92
$11.81K
MELLETT PAUL J
15 Mar 2023
Treasurer and CFO
Sold after exercise
10,340
$44.43
$459.41K
MELLETT PAUL J
15 Mar 2023
Treasurer and CFO
Sold after exercise
100
$43.96
$4.40K
Luly Jay R.
13 Mar 2023
President and CEO
Sold after exercise
1,566
$46.13
$72.24K
Luly Jay R.
13 Mar 2023
President and CEO
Sold after exercise
15,649
$45.31
$709.06K
Luly Jay R.
13 Mar 2023
President and CEO
Sold after exercise
10,697
$44.81
$479.33K
MELLETT PAUL J
9 Feb 2023
Treasurer and CFO
Sell
800
$54.41
$43.53K
MELLETT PAUL J
9 Feb 2023
Treasurer and CFO
Sell
4,200
$53.64
$225.29K
MELLETT PAUL J
9 Jan 2023
Treasurer and CFO
Exercised, kept
2,812
$14.18
$39.87K
Luly Jay R.
19 Dec 2022
President and CEO
Exercised, kept
14,500
$27.58
$399.91K
MELLETT PAUL J
19 Dec 2022
Treasurer and CFO
Exercised, kept
4,148
$14.18
$58.82K
Luly Jay R.
16 Dec 2022
President and CEO
Sold after exercise
13,603
$45.49
$618.80K
Luly Jay R.
16 Dec 2022
President and CEO
Sold after exercise
8,597
$44.54
$382.91K
Luly Jay R.
16 Dec 2022
President and CEO
Sold after exercise
7,800
$43.59
$340.00K
MELLETT PAUL J
17 Jun 2022
Treasurer and CFO
Exercised, kept
3,480
$11.77
$40.96K
Adda Nathalie
4 Apr 2022
Sr. VP & Chief Medical Officer
Sold after exercise
9,009
$73.42
$661.44K
Adda Nathalie
4 Apr 2022
Sr. VP & Chief Medical Officer
Sold after exercise
3,200
$72.65
$232.48K
Adda Nathalie
4 Apr 2022
Sr. VP & Chief Medical Officer
Sold after exercise
18,076
$71.71
$1.30M
Adda Nathalie
4 Apr 2022
Sr. VP & Chief Medical Officer
Sold after exercise
2,500
$70.56
$176.40K
Adda Nathalie
1 Apr 2022
Sr. VP & Chief Medical Officer
Sold after exercise
42,260
$71.32
$3.01M
Adda Nathalie
1 Apr 2022
Sr. VP & Chief Medical Officer
Sold after exercise
8,299
$70.75
$587.15K
CARTER BRUCE L A
21 Mar 2022
Director
Sold after exercise
807
$69.52
$56.10K
CARTER BRUCE L A
21 Mar 2022
Director
Sold after exercise
2,210
$68.66
$151.74K
CARTER BRUCE L A
21 Mar 2022
Director
Sold after exercise
307
$67.23
$20.64K
CARTER BRUCE L A
21 Mar 2022
Director
Sold after exercise
2,676
$66.70
$178.49K
Adda Nathalie
2 Mar 2022
Sr. VP & Chief Medical Officer
Sold after exercise
12,481
$70.07
$874.54K
Adda Nathalie
1 Mar 2022
Sr. VP & Chief Medical Officer
Sold after exercise
100
$71.06
$7.11K
Adda Nathalie
1 Mar 2022
Sr. VP & Chief Medical Officer
Sold after exercise
24,239
$70.26
$1.70M
Luly Jay R.
15 Jan 2022
President and CEO
Exercised, kept
10,063
$11.77
$118.44K
Adda Nathalie
11 Jan 2022
Sr. VP & Chief Medical Officer
Sold after exercise
12,536
$70.13
$879.15K
Adda Nathalie
1 Dec 2021
Sr. VP & Chief Medical Officer
Sold after exercise
201
$90.17
$18.12K
Adda Nathalie
1 Dec 2021
Sr. VP & Chief Medical Officer
Sold after exercise
899
$89.33
$80.31K
Adda Nathalie
1 Dec 2021
Sr. VP & Chief Medical Officer
Sold after exercise
900
$88.31
$79.48K
Adda Nathalie
1 Dec 2021
Sr. VP & Chief Medical Officer
Sold after exercise
1,500
$87.60
$131.40K
Adda Nathalie
1 Dec 2021
Sr. VP & Chief Medical Officer
Sold after exercise
2,700
$86.45
$233.42K
Adda Nathalie
1 Dec 2021
Sr. VP & Chief Medical Officer
Sold after exercise
5,736
$85.49
$490.37K
Adda Nathalie
1 Dec 2021
Sr. VP & Chief Medical Officer
Sold after exercise
1,587
$84.81
$134.59K
Adda Nathalie
1 Nov 2021
Sr. VP & Chief Medical Officer
Sold after exercise
100
$86.21
$8.62K
Adda Nathalie
1 Nov 2021
Sr. VP & Chief Medical Officer
Sold after exercise
7,495
$85.02
$637.22K
Adda Nathalie
1 Nov 2021
Sr. VP & Chief Medical Officer
Sold after exercise
1,952
$84.31
$164.57K
Adda Nathalie
11 Oct 2021
Sr. VP & Chief Medical Officer
Sold after exercise
4,047
$70.34
$284.69K
Adda Nathalie
8 Oct 2021
Sr. VP & Chief Medical Officer
Sold after exercise
13,453
$70.09
$942.93K
Luly Jay R.
15 Sep 2021
President and CEO
Sell
4,516
$59.06
$266.70K
Or Yat Sun
26 Jan 2021
Sr. VP & CSO
Exercised, kept
4,872
$11.77
$57.34K
Or Yat Sun
26 Jan 2021
Sr. VP & CSO
Exercised, kept
3,672
$11.77
$43.22K
Or Yat Sun
26 Jan 2021
Sr. VP & CSO
Exercised, kept
5,149
$14.18
$73.01K
MELLETT PAUL J
8 Jan 2021
Treasurer and CFO
Sell
6,000
$45.58
$273.46K
Gardiner Nathaniel S.
3 Dec 2020
Sr. VP & General Counsel
Exercised, kept
1,667
$30.00
$50.01K
MELLETT PAUL J
11 Nov 2020
Treasurer and CFO
Exercised, kept
3,480
$2.54
$8.85K
Gardiner Nathaniel S.
5 Aug 2020
Sr. VP & General Counsel
Exercised, kept
1,666
$30.00
$49.98K
MELLETT PAUL J
5 May 2020
Treasurer and CFO
Exercised, kept
1,740
$1.21
$2.10K
Gardiner Nathaniel S.
12 Mar 2020
Sr. VP & General Counsel
Exercised, kept
3,000
$30.00
$90.00K
MELLETT PAUL J
2 Jan 2020
Treasurer and CFO
Sell
721
$61.66
$44.46K
MELLETT PAUL J
2 Jan 2020
Treasurer and CFO
Sell
9,279
$60.82
$564.34K
Gardiner Nathaniel S.
22 Nov 2019
Sr. VP & General Counsel
Exercised, kept
1,592
$31.42
$50.02K
Luly Jay R.
8 Oct 2019
President and CEO
Exercised, kept
7,052
$14.18
$100.00K
Gardiner Nathaniel S.
27 Sep 2019
Sr. VP & General Counsel
Exercised, kept
5,000
$30.00
$150.00K
Gardiner Nathaniel S.
26 Jun 2019
Sr. VP & General Counsel
Exercised, kept
3,295
$31.42
$103.53K
CARTER BRUCE L A
11 Mar 2019
Director
Sold after exercise
1,546
$99.16
$153.30K
Gardiner Nathaniel S.
6 Mar 2019
Sr. VP & General Counsel
Exercised, kept
795
$31.42
$24.98K
Gardiner Nathaniel S.
6 Mar 2019
Sr. VP & General Counsel
Exercised, kept
1,724
$34.70
$59.82K
Golumbeski George
4 Mar 2019
Director
Sold after exercise
9,280
$103.65
$961.90K
Or Yat Sun
1 Mar 2019
Sr. VP & CSO
Sell
4,090
$103.84
$424.69K
Or Yat Sun
1 Mar 2019
Sr. VP & CSO
Sell
5,910
$103.32
$610.63K
Gardiner Nathaniel S.
13 Feb 2019
Sr. VP & General Counsel
Sell
3,270
$95.28
$311.56K
MELLETT PAUL J
13 Feb 2019
Treasurer and CFO
Exercised, kept
6,960
$1.51
$10.50K
CARTER BRUCE L A
12 Feb 2019
Director
Sold after exercise
5,000
$90.00
$450.00K
Golumbeski George
12 Feb 2019
Director
Sold after exercise
11,228
$90.07
$1.01M
Or Yat Sun
12 Feb 2019
Sr. VP & CSO
Sell
6,297
$90.07
$567.17K
CARTER BRUCE L A
11 Feb 2019
Director
Sold after exercise
2,734
$90.02
$246.10K
Golumbeski George
11 Feb 2019
Director
Sold after exercise
2,272
$90.03
$204.55K
Or Yat Sun
11 Feb 2019
Sr. VP & CSO
Sold after exercise
171
$91.24
$15.60K
Or Yat Sun
11 Feb 2019
Sr. VP & CSO
Sold after exercise
2,707
$90.11
$243.94K
Or Yat Sun
11 Feb 2019
Sr. VP & CSO
Sold after exercise
18,971
$89.50
$1.70M
Or Yat Sun
11 Feb 2019
Sr. VP & CSO
Sold after exercise
5,835
$88.66
$517.32K
Gardiner Nathaniel S.
22 Jan 2019
Sr. VP & General Counsel
Exercised, kept
2,000
$34.70
$69.40K
Gardiner Nathaniel S.
6 Dec 2018
Sr. VP & General Counsel
Exercised, kept
2,000
$34.70
$69.40K
Ocain Tim
3 Dec 2018
Senior Vice President
Exercised, kept
2,000
$32.27
$64.54K
Ocain Tim
1 Oct 2018
Senior Vice President
Sold after exercise
604
$85.30
$51.52K
Ocain Tim
1 Oct 2018
Senior Vice President
Sold after exercise
14,677
$84.02
$1.23M
Ocain Tim
1 Oct 2018
Senior Vice President
Sold after exercise
6,219
$83.47
$519.13K
Ocain Tim
1 Oct 2018
Senior Vice President
Sold after exercise
3,500
$82.04
$287.14K
Gardiner Nathaniel S.
1 Oct 2018
Sr. VP & General Counsel
Exercised, kept
1,500
$34.70
$52.05K
Adda Nathalie
20 Sep 2018
Sr. VP & Chief Medical Officer
Sold after exercise
1,371
$96.89
$132.84K
Adda Nathalie
20 Sep 2018
Sr. VP & Chief Medical Officer
Sold after exercise
602
$95.84
$57.70K
Adda Nathalie
20 Sep 2018
Sr. VP & Chief Medical Officer
Sold after exercise
1,229
$94.75
$116.45K
Adda Nathalie
20 Sep 2018
Sr. VP & Chief Medical Officer
Sold after exercise
453
$93.90
$42.54K
Adda Nathalie
20 Sep 2018
Sr. VP & Chief Medical Officer
Sold after exercise
500
$93.02
$46.51K
Adda Nathalie
20 Aug 2018
Sr. VP & Chief Medical Officer
Sold after exercise
659
$93.49
$61.61K
Adda Nathalie
20 Aug 2018
Sr. VP & Chief Medical Officer
Sold after exercise
2,224
$92.68
$206.13K
Adda Nathalie
20 Aug 2018
Sr. VP & Chief Medical Officer
Sold after exercise
700
$91.49
$64.04K
Adda Nathalie
20 Aug 2018
Sr. VP & Chief Medical Officer
Sold after exercise
572
$90.58
$51.81K
Luly Jay R.
27 Jul 2018
President and CEO
Exercised, kept
8,498
$11.77
$99.99K
Adda Nathalie
18 Jul 2018
Sr. VP & Chief Medical Officer
Sold after exercise
904
$126.40
$114.26K
Adda Nathalie
18 Jul 2018
Sr. VP & Chief Medical Officer
Sold after exercise
1,621
$125.60
$203.60K
Adda Nathalie
18 Jul 2018
Sr. VP & Chief Medical Officer
Sold after exercise
445
$124.20
$55.27K
Adda Nathalie
18 Jul 2018
Sr. VP & Chief Medical Officer
Sold after exercise
2,075
$123.72
$256.71K
Luly Jay R.
6 Jul 2018
President and CEO
Sell
4,125
$127.12
$524.38K
Luly Jay R.
6 Jul 2018
President and CEO
Sell
7,738
$126.36
$977.79K
Luly Jay R.
6 Jul 2018
President and CEO
Sell
7,538
$125.27
$944.26K
Luly Jay R.
6 Jul 2018
President and CEO
Sell
12,622
$124.26
$1.57M
Luly Jay R.
5 Jul 2018
President and CEO
Sell
2,977
$123.81
$368.57K
Adda Nathalie
18 Jun 2018
Sr. VP & Chief Medical Officer
Sold after exercise
658
$115.89
$76.25K
Adda Nathalie
18 Jun 2018
Sr. VP & Chief Medical Officer
Sold after exercise
2,229
$115.09
$256.54K
Adda Nathalie
18 Jun 2018
Sr. VP & Chief Medical Officer
Sold after exercise
1,268
$113.90
$144.43K
MELLETT PAUL J
18 Jun 2018
Treasurer and CFO
Exercised, kept
6,960
$1.98
$13.80K
MELLETT PAUL J
11 Jun 2018
Treasurer and CFO
Sell
611
$122.17
$74.65K
MELLETT PAUL J
11 Jun 2018
Treasurer and CFO
Sell
5,153
$121.42
$625.66K
MELLETT PAUL J
11 Jun 2018
Treasurer and CFO
Sell
6,336
$120.37
$762.66K
MELLETT PAUL J
11 Jun 2018
Treasurer and CFO
Sell
2,600
$119.35
$310.30K
MELLETT PAUL J
11 Jun 2018
Treasurer and CFO
Sell
300
$117.52
$35.26K
Luly Jay R.
17 May 2018
President and CEO
Sell
10,968
$105.83
$1.16M
Adda Nathalie
16 May 2018
Sr. VP & Chief Medical Officer
Sold after exercise
2,955
$105.57
$311.95K
Adda Nathalie
16 May 2018
Sr. VP & Chief Medical Officer
Sold after exercise
800
$104.81
$83.84K
Adda Nathalie
16 May 2018
Sr. VP & Chief Medical Officer
Sold after exercise
400
$103.85
$41.54K
Luly Jay R.
16 May 2018
President and CEO
Sell
14,032
$105.82
$1.48M
Adda Nathalie
16 Apr 2018
Sr. VP & Chief Medical Officer
Sold after exercise
2,425
$85.92
$208.35K
Adda Nathalie
16 Apr 2018
Sr. VP & Chief Medical Officer
Sold after exercise
1,800
$85.11
$153.21K
MELLETT PAUL J
19 Mar 2018
Treasurer and CFO
Sell
200
$87.94
$17.59K
MELLETT PAUL J
19 Mar 2018
Treasurer and CFO
Sell
3,900
$87.25
$340.29K
MELLETT PAUL J
19 Mar 2018
Treasurer and CFO
Sell
3,900
$86.00
$335.41K
MELLETT PAUL J
19 Mar 2018
Treasurer and CFO
Sell
1,000
$85.05
$85.05K
Gardiner Nathaniel S.
8 Feb 2018
Sr. VP & General Counsel
Exercised, kept
4,300
$34.70
$149.21K
MELLETT PAUL J
11 Apr 2017
Treasurer and CFO
Exercised, kept
29,274
$2.97
$87.06K
Or Yat Sun
4 Jan 2017
Chief Scientific Officer
Sell
13,921
$35.09
$488.50K
Or Yat Sun
29 Nov 2016
Chief Scientific Officer
Sell
13,921
$31.44
$437.61K
