Insider
Date
Role
Action
Shares
Price
Amount
Zaderej Karen L.
18 Aug 2026
Director
Buy
10,600
$4.93
$52.26K
Ribeiro Ramiro
30 Jun 2026
Chief Medical Officer
Sold after exercise
2,438
$15.02
$36.61K
Ribeiro Ramiro
30 Jun 2026
Chief Medical Officer
Sold after exercise
2,437
$15.00
$36.56K
Ribeiro Ramiro
17 Apr 2026
Chief Medical Officer
Sold after exercise
2,437
$15.00
$36.56K
Duker Jay S.
16 Mar 2026
President and CEO
Buy
indirect
1,500
$13.15
$19.72K
Ribeiro Ramiro
4 Mar 2026
Chief Medical Officer
Sold after exercise
2,438
$17.87
$43.57K
Ribeiro Ramiro
17 Feb 2026
Chief Medical Officer
Sold after exercise
2,437
$15.00
$36.56K
Ribeiro Ramiro
5 Jan 2026
Chief Medical Officer
Sold after exercise
42,544
$17.10
$727.32K
Lurker Nancy
4 Dec 2025
Director
Sold on a plan
9,300
$15.11
$140.48K
Cormorant Asset Management, LP
4 Dec 2025
Former 10% Owner
Sell
indirect
60,000
$15.70
$942.24K
Lurker Nancy
28 Nov 2025
Director
Sold on a plan
500
$14.95
$7.48K
Lurker Nancy
26 Nov 2025
Director
Sold on a plan
200
$14.95
$2.99K
Ribeiro Ramiro
11 Nov 2025
Chief Medical Officer
Sold on a plan
2,722
$11.61
$31.60K
Zaderej Karen L.
19 May 2025
Director
Buy
5,000
$5.99
$29.95K
Zaderej Karen L.
16 May 2025
Director
Buy
5,000
$5.81
$29.05K
Zaderej Karen L.
15 May 2025
Director
Buy
5,000
$5.47
$27.35K
Zaderej Karen L.
14 May 2025
Director
Buy
5,000
$5.42
$27.10K
ANDO GORAN
21 Aug 2024
Director
Buy
5,000
$7.95
$39.75K
DICICCO WENDY F
20 Aug 2024
Director
Buy
2,567
$7.79
$20.00K
Zaderej Karen L.
19 Aug 2024
Director
Buy
12,500
$7.98
$99.75K
Lurker Nancy
16 Aug 2024
Director
Buy
3,173
$7.88
$25.00K
GUYER DAVID R
12 Jul 2024
Director
Sold after exercise
11,625
$10.06
$117.00K
GUYER DAVID R
3 Jun 2024
Director
Sold after exercise
11,625
$10.30
$119.70K
GUYER DAVID R
14 May 2024
Director
Sold after exercise
11,625
$12.65
$147.04K
Cormorant Asset Management, LP
6 May 2024
10% owner
Buy
indirect
207,153
$12.36
$2.56M
Cormorant Asset Management, LP
6 May 2024
10% owner
Buy
indirect
642,847
$11.70
$7.52M
Cormorant Asset Management, LP
18 Apr 2024
10% owner
Buy
indirect
186,521
$18.90
$3.53M
Cormorant Asset Management, LP
18 Apr 2024
10% owner
Buy
indirect
395,244
$17.62
$6.96M
Jones David Scott
2 Feb 2024
SVP & Chief Commercial Officer
Sold after exercise
209
$28.49
$5.95K
Jones David Scott
26 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
9,604
$25.27
$242.72K
Jones David Scott
26 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
16,413
$25.45
$417.65K
Paggiarino Dario A.
26 Jan 2024
Chief Medical Officer
Sold after exercise
33,665
$25.77
$867.67K
Paggiarino Dario A.
26 Jan 2024
Chief Medical Officer
Sold after exercise
15,609
$25.41
$396.57K
Paggiarino Dario A.
26 Jan 2024
Chief Medical Officer
Sold after exercise
51
$25.41
$1.30K
Jones David Scott
25 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
300
$25.00
$7.50K
Jones David Scott
25 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
300
$25.00
$7.50K
Paggiarino Dario A.
25 Jan 2024
Chief Medical Officer
Sold after exercise
300
$25.00
$7.50K
Paggiarino Dario A.
25 Jan 2024
Chief Medical Officer
Sold after exercise
300
$25.00
$7.50K
Lurker Nancy
24 Jan 2024
Executive Vice Chair
Sold on a plan
29,956
$24.98
$748.25K
Paggiarino Dario A.
24 Jan 2024
Chief Medical Officer
Sold after exercise
5,651
$25.02
$141.36K
Paggiarino Dario A.
24 Jan 2024
Chief Medical Officer
Sold after exercise
5,600
$25.01
$140.05K
Jones David Scott
24 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
5,600
$25.01
$140.07K
Jones David Scott
24 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
5,700
$25.01
$142.55K
Jones David Scott
23 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
500
$25.00
$12.50K
Jones David Scott
23 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
400
$25.00
$10.00K
Lurker Nancy
23 Jan 2024
Executive Vice Chair
Sold on a plan
5,044
$24.97
$125.95K
Paggiarino Dario A.
23 Jan 2024
Chief Medical Officer
Sold after exercise
3,096
$25.00
$77.40K
Paggiarino Dario A.
23 Jan 2024
Chief Medical Officer
Sold after exercise
2,039
$25.00
$50.98K
Jones David Scott
22 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
28,750
$22.69
$652.25K
Jones David Scott
22 Jan 2024
SVP & Chief Commercial Officer
Sold after exercise
5,416
$22.24
$120.44K
Cormorant Asset Management, LP
11 Jan 2024
10% owner
Buy
indirect
750,000
$19.75
$14.81M
Liu Ye
11 Jan 2024
Director
Sell
indirect
1,910,500
$19.45
$37.16M
Ocumension Therapeutics
11 Jan 2024
Director
Sell
1,910,500
$19.45
$37.16M
Cormorant Asset Management, LP
9 Jan 2024
10% owner
Buy
indirect
105,000
$21.32
$2.24M
Paggiarino Dario A.
8 Jan 2024
Chief Medical Officer
Sold after exercise
22,913
$21.13
$484.12K
Paggiarino Dario A.
13 Dec 2023
Chief Medical Officer
Sold after exercise
1,458
$20.00
$29.16K
Cormorant Asset Management, LP
8 Dec 2023
10% owner
Buy
indirect
588,235
$17.00
$10.00M
Liu Ye
6 Dec 2023
Director
Sell
indirect
266,242
$18.41
$4.90M
Ocumension Therapeutics
6 Dec 2023
Director
Sell
266,242
$18.41
$4.90M
Liu Ye
5 Dec 2023
Director
Sell
indirect
733,758
$19.91
$14.61M
Ocumension Therapeutics
5 Dec 2023
Director
Sell
733,758
$19.91
$14.61M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
8,260
$34.49
$284.89K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
19,866
$33.75
$670.48K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
41,824
$33.08
$1.38M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
86,713
$31.83
$2.76M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
15,582
$30.74
$478.99K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
18,601
$29.91
$556.36K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
8,168
$28.78
$235.08K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
27,425
$27.87
$764.33K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
53,109
$26.73
$1.42M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
65,086
$25.88
$1.68M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
39,899
$24.87
$992.29K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
37,081
$24.01
$890.31K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
28,090
$22.80
$640.45K
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
79,805
$21.87
$1.75M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
122,625
$20.62
$2.53M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
945,664
$19.88
$18.80M
Cormorant Asset Management, LP
4 Dec 2023
10% owner
Buy
indirect
321,259
$18.80
$6.04M
Lurker Nancy
4 Dec 2023
Executive Vice Chair
Sold on a plan
20,000
$20.76
$415.20K
Paggiarino Dario A.
4 Dec 2023
Chief Medical Officer
Sold after exercise
30,625
$22.00
$673.75K
Pine Michael Craig
4 Dec 2023
Chief Corp Dev.&Strat. Officer
Sold after exercise
45,000
$22.00
$990.00K
EW Healthcare Partners, L.P.
1 Sep 2023
10% owner
Sell
indirect
20,000
$9.90
$197.98K
EW Healthcare Partners, L.P.
31 Aug 2023
10% owner
Sell
indirect
7,017
$11.02
$77.34K
EW Healthcare Partners, L.P.
31 Aug 2023
10% owner
Sell
indirect
71,478
$10.17
$726.72K
EW Healthcare Partners, L.P.
30 Aug 2023
10% owner
Sell
indirect
327
$11.36
$3.71K
EW Healthcare Partners, L.P.
30 Aug 2023
10% owner
Sell
indirect
60,649
$10.92
$662.43K
EW Healthcare Partners, L.P.
29 Aug 2023
10% owner
Sell
indirect
565
$11.56
$6.53K
EW Healthcare Partners, L.P.
29 Aug 2023
10% owner
Sell
indirect
87,289
$10.74
$937.69K
EW Healthcare Partners, L.P.
28 Aug 2023
10% owner
Sell
indirect
60,858
$11.71
$712.65K
EW Healthcare Partners, L.P.
25 Aug 2023
10% owner
Sell
indirect
54,656
$11.19
$611.35K
EW Healthcare Partners, L.P.
25 Aug 2023
10% owner
Sell
indirect
30,000
$10.67
$320.13K
EW Healthcare Partners, L.P.
24 Aug 2023
10% owner
Sell
indirect
139,280
$14.62
$2.04M
EW Healthcare Partners, L.P.
23 Aug 2023
10% owner
Sell
indirect
121,103
$13.05
$1.58M
EW Healthcare Partners, L.P.
22 Aug 2023
10% owner
Sell
indirect
46,778
$14.62
$683.83K
Liu Ye
30 May 2023
Director
Sell
indirect
1
$6.00
$6.00
Pine Michael Craig
14 Mar 2022
Chief Corp Dev.&Strat. Officer
Buy
1,000
$12.21
$12.21K
Lurker Nancy
15 Nov 2021
President & CEO
Sell
10,000
$20.15
$201.48K
Elston George
4 Sep 2020
Chief Financial Officer
Buy
10,000
$0.48
$4.80K
Elston George
24 Aug 2020
Chief Financial Officer
Buy
10,000
$0.61
$6.11K
Elston George
12 Mar 2020
Chief Financial Officer
Buy
10,000
$0.96
$9.60K
Lurker Nancy
10 Mar 2020
President & CEO
Buy
98,000
$1.06
$104.03K
Elston George
15 Nov 2019
Chief Financial Officer
Buy
10,000
$1.43
$14.29K
Mazzo David J
9 Oct 2019
Director
Exercised, kept
33,333
$1.95
$65.00K
Landis John B.
13 May 2019
Director
Buy
40,000
$1.74
$69.60K
Duker Jay S.
12 Apr 2019
Director
Exercised, kept
20,000
$1.77
$35.40K
Ross Leonard S
1 Apr 2019
See Remarks
Exercised, kept
5,000
$1.81
$9.05K
Duker Jay S.
1 Apr 2019
Director
Buy
5,000
$1.89
$9.45K
Godshall Douglas Evan
29 Mar 2019
Director
Buy
17,000
$1.75
$29.78K
Mazzo David J
29 Mar 2019
Director
Exercised, kept
20,000
$1.77
$35.40K
Lurker Nancy
29 Mar 2019
President & CEO
Buy
28,500
$1.76
$50.25K
ROGERS MICHAEL W
15 Nov 2018
Director
Exercised, kept
100,000
$1.13
$113.00K
EW Healthcare Partners, L.P.
25 Jun 2018
10% owner
Buy
indirect
652,244
$1.27
$825.09K
EW Healthcare Partners, L.P.
25 Jun 2018
10% owner
Buy
16,211,822
$1.27
$20.51M
Mazzo David J
20 Apr 2018
Director
Exercised, kept
120,000
$1.13
$135.60K
EW Healthcare Partners, L.P.
28 Mar 2018
10% owner
Buy
indirect
332,863
$1.10
$366.15K
EW Healthcare Partners, L.P.
28 Mar 2018
10% owner
Buy
8,273,461
$1.10
$9.10M
Lurker Nancy
14 Jun 2017
President and CEO
Buy
56,700
$1.76
$99.96K
