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Praxis Precision Medicines, Inc.

PRAX Net selling
CIK 0001689548 #930 in the set updated 17 Sep 2026
Bought (120 mo)
$602.91K
out of their own pocket, the only kind of buying there is
Sold (120 mo)
$61.61M
$0.00 on a plan · $12.16M straight out of an exercise
Sold at will
$49.45M
21 of 41 sales
Net
−$61.00M
−$48.84M against sales at will

By person

20 insiders · 60 transactions
27.0×

Marcio Souza holds 27.0 times base salary in stock. $17.84M of shares against $659.20K in salary for 2025.

Salary from the company's own proxy. The shares are what Marcio Souza last reported holding, valued at $315.71, the price Common Stock was last bought or sold at on the open market here, on 24 Jun 2026.

Insider
Role
Bought
Sold
Net
Holding
Of company
Worth
Change
Adage Capital Management, L.P. entity
10% owner
—
$33.20M (10)
−$33.20M
2,060,175
7.38%
$650.41M
+18.0%
BSOF Parallel Master Fund L.P. entity
10% owner
—
$16.25M (11)
−$16.25M
0
0.0000%
$0.00
—
Nemiroff Alex
General Counsel and Secretary
$12.23K (1)
$5.51M (5) scheduled
−$5.50M
26,011
0.0932%
$8.21M
—
DeSimone Jill
Director
$25.38K (1)
$3.61M (12) scheduled
−$3.59M
2,337
0.0084%
$737.80K
—
Mastrocola Lauren
Principal Accounting Officer
$5.78K (1)
$3.04M (3) scheduled
−$3.03M
13,573
0.0486%
$4.28M
—
Souza Marcio
Chief Executive Officer
$371.81K (6)
—
+$371.81K
56,495
0.2023%
$17.84M
—
Kelly Timothy Edwin
Chief Financial Officer
$100.72K (3)
—
+$100.72K
31,167
0.1116%
$9.84M
—
MITCHELL DEAN J
Director
$87.00K (2)
—
+$87.00K
18,622
0.0667%
$5.88M
—
Clarus Lifesciences III, L.P.
10% owner
—
—
—
4,894,109
17.53%
$1.55B
—
Vitorovic Stefan
Director
—
—
—
2,689,329
9.63%
$849.03M
—
Novo Holdings A/S entity
10% owner
—
—
—
2,442,080
8.75%
$770.98M
—
Ravina Bernard
Chief Medical Officer
—
—
—
99,476
0.3563%
$31.41M
+802.6%
Sweeny Nicole
Chief Commercial Officer
—
—
—
38,619
0.1383%
$12.19M
—
Sniecinski Megan
Chief Operating Officer
—
—
—
28,664
0.1027%
$9.05M
+37.0%
YOUNG WILLIAM D
Director
—
—
—
3,269
0.0117%
$1.03M
—
Arbuckle Stuart A
Director
—
—
—
2,537
0.0091%
$800.94K
—
KINDLER JEFFREY B
Director
—
—
—
2,537
0.0091%
$800.94K
—
Norden Gregory
Director
—
—
—
1,559
0.0056%
$492.18K
—
Chodakewitz Jeffrey
Director
—
—
—
1,371
0.0049%
$432.83K
—
Cudkowicz Merit Ester
Director
—
—
—
1,371
0.0049%
$432.83K
—

Individual transactions

60
Insider
Date
Role
Action
Shares
Price
Amount
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
837
$315.71
$264.25K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
1,279
$314.90
$402.76K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
504
$313.66
$158.09K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
1,004
$312.83
$314.08K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
2,854
$311.91
$890.20K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
1,750
$310.89
$544.06K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
999
$309.38
$309.07K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
1,240
$308.24
$382.22K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
683
$306.77
$209.52K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
320
$305.31
$97.70K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
120
$303.13
$36.38K
DeSimone Jill
24 Jun 2026
Director
Sold after exercise
10
$301.44
$3.01K
Mastrocola Lauren
20 Nov 2025
Principal Accounting Officer
Sold after exercise
2,145
$192.71
$413.37K
Mastrocola Lauren
20 Nov 2025
Principal Accounting Officer
Sold after exercise
11,455
$191.96
$2.20M
Nemiroff Alex
20 Nov 2025
General Counsel and Secretary
Sold after exercise
9,100
$194.30
$1.77M
Nemiroff Alex
20 Nov 2025
General Counsel and Secretary
Sold after exercise
977
$193.23
$188.79K
Nemiroff Alex
20 Nov 2025
General Counsel and Secretary
Sold after exercise
13,339
$192.53
$2.57M
Nemiroff Alex
20 Nov 2025
General Counsel and Secretary
Sold after exercise
1,714
$190.86
$327.14K
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
19,198
$140.00
$2.69M
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
308
$132.19
$40.71K
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
487
$131.64
$64.11K
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
1,661
$130.10
$216.09K
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
250,000
$104.31
$26.08M
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
27,287
$101.00
$2.76M
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
559
$100.11
$55.96K
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
1,363
$92.03
$125.44K
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
447
$91.04
$40.69K
Adage Capital Management, L.P.
16 Oct 2025
10% owner
Sell indirect
12,600
$90.00
$1.13M
MITCHELL DEAN J
24 Sep 2025
Director
Exercised, kept
1,753
$44.04
$77.20K
MITCHELL DEAN J
24 Sep 2025
Director
Exercised, kept
8,566
$44.25
$379.05K
MITCHELL DEAN J
24 Sep 2025
Director
Exercised, kept
1,932
$14.36
$27.74K
Mastrocola Lauren
14 Nov 2024
Principal Accounting Officer
Sold after exercise
5,188
$81.78
$424.32K
Nemiroff Alex
14 Nov 2024
General Counsel and Secretary
Sold after exercise
8,239
$80.20
$660.83K
DeSimone Jill
5 Oct 2023
Director
Buy
14,500
$1.75
$25.38K
Souza Marcio
27 Jun 2023
Chief Executive Officer
Buy indirect
10,000
$1.06
$10.59K
Kelly Timothy Edwin
24 Mar 2023
Chief Financial Officer
Buy
8,000
$0.87
$7.00K
MITCHELL DEAN J
24 Mar 2023
Director
Buy
50,000
$0.84
$41.82K
Souza Marcio
23 Mar 2023
Chief Executive Officer
Buy indirect
35,002
$0.86
$30.21K
Souza Marcio
23 Mar 2023
Chief Executive Officer
Buy
35,000
$0.86
$30.16K
Mastrocola Lauren
16 Jun 2022
Principal Accounting Officer
Buy
3,000
$1.93
$5.78K
Nemiroff Alex
13 Jun 2022
General Counsel and Secretary
Buy
7,500
$1.63
$12.23K
Kelly Timothy Edwin
9 Jun 2022
Chief Financial Officer
Buy
10,000
$1.77
$17.65K
MITCHELL DEAN J
8 Jun 2022
Director
Buy
25,000
$1.81
$45.19K
Souza Marcio
8 Jun 2022
Chief Executive Officer
Buy
27,000
$1.85
$49.89K
BSOF Parallel Master Fund L.P.
6 Oct 2021
10% owner
Sell indirect
400,000
$17.50
$7.00M
BSOF Parallel Master Fund L.P.
5 Oct 2021
10% owner
Sell indirect
23,946
$19.15
$458.57K
BSOF Parallel Master Fund L.P.
1 Oct 2021
10% owner
Sell indirect
22,600
$19.13
$432.34K
Kelly Timothy Edwin
31 Aug 2021
Chief Financial Officer
Buy
3,905
$19.48
$76.07K
BSOF Parallel Master Fund L.P.
23 Aug 2021
10% owner
Sell indirect
771
$20.04
$15.45K
BSOF Parallel Master Fund L.P.
23 Aug 2021
10% owner
Sell indirect
351,625
$19.00
$6.68M
Souza Marcio
18 Aug 2021
Chief Executive Officer
Buy
9,542
$15.79
$150.67K
BSOF Parallel Master Fund L.P.
18 Aug 2021
10% owner
Sell indirect
3,000
$15.88
$47.64K
BSOF Parallel Master Fund L.P.
12 Aug 2021
10% owner
Sell indirect
10,060
$13.92
$140.04K
BSOF Parallel Master Fund L.P.
11 Aug 2021
10% owner
Sell indirect
17,222
$15.03
$258.85K
BSOF Parallel Master Fund L.P.
3 Aug 2021
10% owner
Sell indirect
22,300
$14.99
$334.28K
BSOF Parallel Master Fund L.P.
2 Aug 2021
10% owner
Sell indirect
40,000
$15.78
$631.20K
BSOF Parallel Master Fund L.P.
30 Jul 2021
10% owner
Sell indirect
15,854
$15.68
$248.59K
Ravina Bernard
4 Jan 2021
Chief Medical Officer
Exercised, kept
45,000
$2.27
$102.15K
Souza Marcio
10 Nov 2020
Chief Executive Officer
Buy
3,846
$26.08
$100.30K
Mastrocola Lauren
2 Nov 2020
Principal Accounting Officer
Exercised, kept
12,218
$3.30
$40.32K

What was left out

Form 4 filings counted 181
Amendments (4/A) skipped 2
Filings about a different issuer 0
Unreadable filings 0
Joint filings 11
Sales on a Rule 10b5-1 plan 0
Sales straight out of an exercise 20
Sales at will 21
Transactions with no price 0
Shares from compensation/vesting 24,162,453
Sales filed before the plan box existed 11
History held since 20 Oct 2020