Insider
Date
Role
Action
Shares
Price
Amount
VON RICKENBACH JOSEF H
27 May 2026
Director
Buy
4,500
$1.07
$4.82K
VON RICKENBACH JOSEF H
26 May 2026
Director
Buy
23,190
$1.06
$24.47K
VON RICKENBACH JOSEF H
22 May 2026
Director
Buy
15,950
$1.05
$16.71K
VON RICKENBACH JOSEF H
21 May 2026
Director
Buy
3,420
$1.04
$3.56K
WINDSOR JAMES BRIAN
30 Apr 2026
See Remarks
Buy
25,000
$1.00
$25.00K
Voss Capital, LP
14 Nov 2025
10% owner
Buy
indirect
104,183
$1.22
$127.59K
Voss Capital, LP
28 Oct 2025
10% owner
Buy
indirect
178,392
$1.39
$247.96K
Voss Capital, LP
27 Oct 2025
10% owner
Buy
indirect
4,840
$1.37
$6.62K
Voss Capital, LP
27 Oct 2025
10% owner
Buy
indirect
92,642
$1.37
$126.92K
Voss Capital, LP
24 Oct 2025
10% owner
Buy
indirect
30,176
$1.39
$41.96K
WINDSOR JAMES BRIAN
5 Dec 2024
President and CEO
Buy
indirect
161
$2.25
$362.25
WINDSOR JAMES BRIAN
5 Dec 2024
President and CEO
Buy
indirect
239
$2.24
$535.36
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
17 Jun 2024
10% owner
Sell
4,707
$3.25
$15.30K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
14 Jun 2024
10% owner
Sell
1,900
$3.30
$6.27K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
12 Jun 2024
10% owner
Sell
1
$3.28
$3.28
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
12 Jun 2024
10% owner
Sell
9,341
$3.25
$30.36K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
11 Jun 2024
10% owner
Sell
502
$3.35
$1.68K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
11 Jun 2024
10% owner
Sell
5,250
$3.25
$17.06K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 Jun 2024
10% owner
Sell
9,577
$3.30
$31.60K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
7 Jun 2024
10% owner
Sell
176
$3.30
$580.80
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
7 Jun 2024
10% owner
Sell
1,564
$3.25
$5.08K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
6 Jun 2024
10% owner
Sell
3,184
$3.30
$10.51K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
6 Jun 2024
10% owner
Sell
1,100
$3.27
$3.60K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
5 Jun 2024
10% owner
Sell
6,291
$3.30
$20.76K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
25
$4.32
$108.00
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
2,903
$4.29
$12.45K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
200
$4.29
$857.00
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
337
$4.28
$1.44K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
200
$4.28
$855.00
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
100
$4.27
$427.00
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
317
$4.27
$1.35K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
310
$4.26
$1.32K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
7,923
$4.25
$33.67K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
400
$4.18
$1.67K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
670
$4.15
$2.78K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
1,600
$4.15
$6.63K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
380
$4.13
$1.57K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
1,750
$4.12
$7.21K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
100
$4.11
$411.00
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
1 May 2024
10% owner
Sell
3,100
$4.10
$12.71K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
30 Apr 2024
10% owner
Sell
45
$5.00
$225.00
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
30 Apr 2024
10% owner
Sell
45
$4.95
$222.75
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
29 Apr 2024
10% owner
Sell
448
$5.03
$2.25K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
29 Apr 2024
10% owner
Sell
13
$5.01
$65.07
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
29 Apr 2024
10% owner
Sell
3,231
$5.00
$16.16K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
29 Apr 2024
10% owner
Sell
100
$4.94
$494.00
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
29 Apr 2024
10% owner
Sell
274
$4.93
$1.35K
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
29 Apr 2024
10% owner
Sell
6,680
$4.92
$32.87K
WINDSOR JAMES BRIAN
15 Dec 2023
President and COO
Buy
indirect
225
$3.37
$758.25
WINDSOR JAMES BRIAN
20 Nov 2023
President and COO
Buy
5,076
$1.97
$9.99K
Satter Muneer A
8 Jan 2021
See Remarks
Buy
indirect
9,000,000
$1.10
$9.90M
Ambros Reinhard J.
15 Jun 2020
Director
Buy
5,800
$1.22
$7.08K
Satter Muneer A
8 Jun 2020
Director
Buy
indirect
3,700,000
$1.10
$4.07M
VON RICKENBACH JOSEF H
8 Jun 2020
Director
Buy
227,272
$1.10
$250.00K
Bailey Jeffrey Allen
15 Nov 2019
Director
Buy
39,142
$0.51
$19.96K
Bailey Jeffrey Allen
14 Nov 2019
Director
Buy
15,858
$0.51
$8.09K
Bailey Jeffrey Allen
12 Nov 2019
Director
Buy
19,894
$0.53
$10.54K
VON RICKENBACH JOSEF H
13 Sep 2019
Director
Buy
25,000
$0.97
$24.26K
VON RICKENBACH JOSEF H
12 Sep 2019
Director
Buy
88,145
$0.98
$86.25K
VON RICKENBACH JOSEF H
4 Sep 2019
Director
Buy
23,225
$0.71
$16.58K
VON RICKENBACH JOSEF H
3 Sep 2019
Director
Buy
13,466
$0.70
$9.43K
VON RICKENBACH JOSEF H
30 Aug 2019
Director
Buy
15,000
$0.73
$10.97K
VON RICKENBACH JOSEF H
29 Aug 2019
Director
Buy
3,600
$0.77
$2.77K
Vukovic Vojo
16 Aug 2019
SVP, Chief Medical Officer
Buy
75,000
$0.59
$44.45K
Gregory Kathryn
13 Aug 2019
SVP, Chief Business Officer
Buy
45,000
$0.65
$29.03K
Novartis Bioventures Ltd
1 Apr 2019
10% owner
Sell
20,610
$1.90
$39.16K
Novartis Bioventures Ltd
29 Mar 2019
10% owner
Sell
106,540
$1.85
$197.10K
Novartis Bioventures Ltd
15 Mar 2019
10% owner
Sell
43,800
$1.92
$84.10K
Novartis Bioventures Ltd
14 Mar 2019
10% owner
Sell
13,800
$1.88
$25.94K
Novartis Bioventures Ltd
13 Mar 2019
10% owner
Sell
132,738
$2.12
$281.40K
Novartis Bioventures Ltd
20 Aug 2018
10% owner
Sell
20,388
$2.30
$46.89K
Novartis Bioventures Ltd
17 Aug 2018
10% owner
Sell
8,700
$2.10
$18.27K
Novartis Bioventures Ltd
16 Aug 2018
10% owner
Sell
8,808
$2.10
$18.50K
Novartis Bioventures Ltd
15 Aug 2018
10% owner
Sell
2,635
$2.15
$5.67K
Novartis Bioventures Ltd
14 Aug 2018
10% owner
Sell
3,300
$2.26
$7.46K
Novartis Bioventures Ltd
13 Aug 2018
10% owner
Sell
1,600
$2.36
$3.78K
Novartis Bioventures Ltd
10 Aug 2018
10% owner
Sell
5,615
$2.44
$13.70K
LONGENECKER JOHN P PHD
10 Aug 2018
President and CEO
Buy
10,000
$2.45
$24.50K
Novartis Bioventures Ltd
9 Aug 2018
10% owner
Sell
235
$2.48
$582.80
Novartis Bioventures Ltd
8 Aug 2018
10% owner
Sell
1,000
$2.78
$2.78K
Novartis Bioventures Ltd
7 Aug 2018
10% owner
Sell
1,739
$2.97
$5.16K
Novartis Bioventures Ltd
6 Aug 2018
10% owner
Sell
2,942
$3.02
$8.88K
Novartis Bioventures Ltd
2 Aug 2018
10% owner
Sell
4,702
$3.33
$15.66K
Novartis Bioventures Ltd
1 Aug 2018
10% owner
Sell
8,181
$3.22
$26.34K
Novartis Bioventures Ltd
31 Jul 2018
10% owner
Sell
4,500
$3.07
$13.82K
Novartis Bioventures Ltd
30 Jul 2018
10% owner
Sell
2,000
$3.27
$6.54K
Novartis Bioventures Ltd
27 Jul 2018
10% owner
Sell
6,458
$3.38
$21.83K
Novartis Bioventures Ltd
26 Jul 2018
10% owner
Sell
7,937
$3.63
$28.81K
Novartis Bioventures Ltd
25 Jul 2018
10% owner
Sell
12,460
$3.84
$47.85K
Novartis Bioventures Ltd
24 Jul 2018
10% owner
Sell
700
$4.11
$2.88K
Novartis Bioventures Ltd
23 Jul 2018
10% owner
Sell
30,600
$4.25
$130.05K
Novartis Bioventures Ltd
17 Jul 2018
10% owner
Sell
12,500
$4.71
$58.88K
Novartis Bioventures Ltd
16 Jul 2018
10% owner
Sell
300
$5.15
$1.55K
APPLE TREE PARTNERS II LP
26 Jun 2018
10% owner
Sell
10,528
$5.45
$57.42K
APPLE TREE PARTNERS II LP
25 Jun 2018
10% owner
Sell
913
$5.86
$5.35K
APPLE TREE PARTNERS II LP
22 Jun 2018
10% owner
Sell
94,816
$5.98
$566.74K
APPLE TREE PARTNERS II LP
21 Jun 2018
10% owner
Sell
1,447
$5.30
$7.67K
APPLE TREE PARTNERS II LP
20 Jun 2018
10% owner
Sell
5,200
$5.30
$27.56K
APPLE TREE PARTNERS II LP
19 Jun 2018
10% owner
Sell
139
$5.30
$736.70
APPLE TREE PARTNERS II LP
18 Jun 2018
10% owner
Sell
1,432
$5.35
$7.66K
APPLE TREE PARTNERS II LP
15 Jun 2018
10% owner
Sell
7,961
$5.32
$42.35K
APPLE TREE PARTNERS II LP
12 Jun 2018
10% owner
Sell
10,843
$5.40
$58.56K
APPLE TREE PARTNERS II LP
11 Jun 2018
10% owner
Sell
18,525
$5.41
$100.24K
APPLE TREE PARTNERS II LP
8 Jun 2018
10% owner
Sell
9,617
$5.40
$51.96K
Dougherty Donald
8 Jun 2018
SVP & Chief Financial Officer
Buy
3,000
$5.40
$16.20K
APPLE TREE PARTNERS II LP
7 Jun 2018
10% owner
Sell
20
$5.48
$109.50
Aivado Manuel
6 Jun 2018
See Remarks
Buy
1,000
$5.61
$5.61K
Dougherty Donald
1 Jun 2018
SVP & Chief Financial Officer
Buy
2,000
$5.24
$10.48K
APPLE TREE PARTNERS II LP
19 Apr 2018
10% owner
Sell
104,799
$6.29
$659.50K
APPLE TREE PARTNERS II LP
17 Apr 2018
10% owner
Sell
3,105
$7.05
$21.89K
APPLE TREE PARTNERS II LP
9 Jan 2018
10% owner
Sell
150,000
$9.80
$1.47M
Novartis Bioventures Ltd
5 Jul 2017
10% owner
Buy
266,667
$15.00
$4.00M
Ambros Reinhard J.
5 Jul 2017
Director
Buy
indirect
266,667
$15.00
$4.00M
Kapnick Scott
5 Jul 2017
Director
Buy
indirect
66,666
$15.00
$999.99K
Kapnick Scott
5 Jul 2017
Director
Buy
159,307
$15.00
$2.39M
CVF, LLC
5 Jul 2017
10% owner
Buy
180,000
$15.00
$2.70M
ROCHE HOLDING LTD
5 Jul 2017
10% owner
Buy
119,400
$15.00
$1.79M
KCK LTD.
5 Jul 2017
10% owner
Buy
200,000
$15.00
$3.00M
Satter Muneer A
5 Jul 2017
10% owner
Buy
indirect
33,333
$15.00
$500.00K
EXCEL MEDICAL FUND LP
5 Jul 2017
10% owner
Buy
60,000
$15.00
$900.00K
Sigma Emerging Markets Ltd.
5 Jul 2017
10% owner
Buy
190,000
$15.00
$2.85M
Gallagher Brian M. Jr.
5 Jul 2017
Director
Buy
indirect
273,333
$15.00
$4.10M
AJU IB Investment Co., Ltd.
5 Jul 2017
10% owner
Buy
indirect
24,929
$15.00
$373.94K
LV Management Group, LLC
5 Jul 2017
Former 10% owner
Buy
indirect
250,000
$15.00
$3.75M
Shanafelt Armen
5 Jul 2017
Director
Buy
indirect
250,000
$15.00
$3.75M
