Insider
Date
Role
Action
Shares
Price
Amount
Jessica Newcomb
2 Nov 2026
Principal Accounting Officer
Sold on a plan
1,460
$22.98
$33.55K
Jessica Newcomb
2 Nov 2026
Principal Accounting Officer
Sold on a plan
5,571
$22.28
$124.11K
Adam Crystal
2 Nov 2026
President, R&D
Sold after exercise
1,100
$22.99
$25.29K
Adam Crystal
2 Nov 2026
President, R&D
Sold after exercise
3,900
$22.26
$86.82K
Adam Crystal
1 Oct 2026
President, R&D
Sold after exercise
600
$25.32
$15.19K
Adam Crystal
1 Oct 2026
President, R&D
Sold after exercise
26,400
$24.45
$645.60K
Jessica Newcomb
22 Sep 2026
Principal Accounting Officer
Sold on a plan
2,400
$25.17
$60.41K
Jessica Newcomb
22 Sep 2026
Principal Accounting Officer
Sold on a plan
5,100
$23.97
$122.24K
Jessica Newcomb
22 Sep 2026
Principal Accounting Officer
Sold on a plan
700
$22.80
$15.96K
Adam Crystal
1 Sep 2026
President, R&D
Sold after exercise
27,000
$22.37
$603.91K
Adam Crystal
3 Aug 2026
President, R&D
Sold after exercise
21,733
$27.35
$594.42K
Adam Crystal
3 Aug 2026
President, R&D
Sold after exercise
5,267
$26.79
$141.10K
Adam Crystal
1 Jul 2026
President, R&D
Sold after exercise
7,371
$30.25
$222.95K
Adam Crystal
1 Jul 2026
President, R&D
Sold after exercise
19,629
$29.34
$575.96K
Adam Crystal
1 Jun 2026
President, R&D
Sold after exercise
20,860
$23.06
$480.94K
Adam Crystal
1 Jun 2026
President, R&D
Sold after exercise
6,140
$22.25
$136.63K
Adam Crystal
1 May 2026
President, R&D
Sold after exercise
1,100
$22.00
$24.20K
Adam Crystal
1 May 2026
President, R&D
Sold after exercise
25,900
$21.19
$548.90K
Adam Crystal
15 Apr 2026
President, R&D
Sold after exercise
38,460
$25.00
$961.50K
Adam Crystal
1 Apr 2026
President, R&D
Sold after exercise
27,000
$21.20
$572.48K
Adam Crystal
25 Mar 2026
President, R&D
Sold after exercise
12,000
$20.11
$241.32K
Adam Crystal
5 Mar 2026
President, R&D
Sold on a plan
20,251
$15.00
$303.77K
Adam Crystal
25 Feb 2026
President, R&D
Sold on a plan
54,345
$12.77
$694.21K
Adam Crystal
3 Feb 2026
President, R&D
Sell
201
$12.90
$2.59K
Adam Crystal
3 Feb 2026
President, R&D
Sell
18,251
$12.26
$223.71K
Barbara Weber
3 Feb 2026
Director, Executive Chair
Sell
333
$12.90
$4.29K
Barbara Weber
3 Feb 2026
Director, Executive Chair
Sell
30,186
$12.26
$370.00K
Daniella Beckman
3 Feb 2026
Chief Financial Officer
Sell
113
$12.90
$1.46K
Daniella Beckman
3 Feb 2026
Chief Financial Officer
Sell
10,204
$12.26
$125.07K
Third Rock Ventures IV, L.P.
23 Oct 2025
10% owner
Sell
477,401
$10.15
$4.85M
Third Rock Ventures IV, L.P.
25 Sep 2025
10% owner
Sell
500,000
$8.02
$4.01M
Third Rock Ventures IV, L.P.
16 Sep 2025
10% owner
Sell
363,541
$7.04
$2.56M
Third Rock Ventures IV, L.P.
8 Sep 2025
10% owner
Sell
86,459
$7.04
$608.63K
Third Rock Ventures IV, L.P.
5 Sep 2025
10% owner
Sell
642,906
$7.00
$4.50M
Third Rock Ventures IV, L.P.
22 Aug 2025
10% owner
Sell
302,194
$7.00
$2.12M
Third Rock Ventures IV, L.P.
19 Aug 2025
10% owner
Sell
1,100,000
$7.01
$7.71M
Barbara Weber
5 Feb 2025
Chief Executive Officer
Sell
9,013
$3.16
$28.49K
Adam Crystal
5 Feb 2025
See Remarks
Sell
6,851
$3.16
$21.66K
Daniella Beckman
5 Feb 2025
Chief Financial Officer
Sell
3,948
$3.16
$12.48K
Douglas Barry
5 Feb 2025
General Counsel
Sell
2,556
$3.16
$8.08K
Barbara Weber
4 Feb 2025
Chief Executive Officer
Sell
9,778
$2.99
$29.22K
Adam Crystal
4 Feb 2025
See Remarks
Sell
7,432
$2.99
$22.21K
Daniella Beckman
4 Feb 2025
Chief Financial Officer
Sell
4,284
$2.99
$12.80K
Douglas Barry
4 Feb 2025
General Counsel
Sell
2,774
$2.99
$8.29K
Mace Rothenberg
18 Nov 2024
Director
Buy
10,000
$3.78
$37.80K
Mace Rothenberg
14 Nov 2024
Director
Buy
10,000
$3.62
$36.20K
EcoR1 Capital, LLC
7 Nov 2024
10% owner
Sell
indirect
1,143,124
$2.92
$3.33M
EcoR1 Capital, LLC
7 Nov 2024
10% owner
Sell
indirect
62,318
$3.29
$205.11K
Boxer Capital Management, LLC
6 Nov 2024
See remarks
Sell
indirect
3,080,000
$3.14
$9.67M
EcoR1 Capital, LLC
6 Nov 2024
10% owner
Sell
indirect
1,494,558
$3.28
$4.90M
Boxer Capital Management, LLC
25 Oct 2024
See remarks.
Sell
633,000
$6.87
$4.35M
Boxer Capital Management, LLC
22 Oct 2024
See remarks
Sell
250,000
$6.78
$1.70M
Boxer Capital Management, LLC
21 Oct 2024
See remarks
Sell
625,000
$7.05
$4.41M
Third Rock Ventures IV, L.P.
13 Sep 2024
10% owner
Sell
67,400
$10.53
$709.76K
Third Rock Ventures IV, L.P.
5 Sep 2024
10% owner
Sell
75,000
$11.56
$867.14K
Third Rock Ventures IV, L.P.
30 Aug 2024
10% owner
Sell
175,000
$11.60
$2.03M
Third Rock Ventures IV, L.P.
27 Aug 2024
10% owner
Sell
25,000
$11.55
$288.67K
Third Rock Ventures IV, L.P.
19 Aug 2024
10% owner
Sell
150,000
$10.09
$1.51M
Third Rock Ventures IV, L.P.
16 Aug 2024
10% owner
Sell
135,000
$9.79
$1.32M
Third Rock Ventures IV, L.P.
1 Aug 2024
10% owner
Sell
40,000
$9.80
$392.00K
Third Rock Ventures IV, L.P.
31 Jul 2024
10% owner
Sell
100,000
$9.93
$993.38K
Third Rock Ventures IV, L.P.
30 Jul 2024
10% owner
Sell
95,000
$9.80
$931.11K
Third Rock Ventures IV, L.P.
26 Jul 2024
10% owner
Sell
50,000
$9.84
$491.95K
Third Rock Ventures IV, L.P.
25 Jul 2024
10% owner
Sell
100,599
$9.87
$992.77K
Third Rock Ventures IV, L.P.
24 Jul 2024
10% owner
Sell
200,000
$9.82
$1.96M
Third Rock Ventures IV, L.P.
23 Jul 2024
10% owner
Sell
125,000
$9.79
$1.22M
Third Rock Ventures IV, L.P.
22 Jul 2024
10% owner
Sell
262,740
$9.78
$2.57M
Third Rock Ventures IV, L.P.
18 Jul 2024
10% owner
Sell
191,490
$9.81
$1.88M
Third Rock Ventures IV, L.P.
17 Jul 2024
10% owner
Sell
550,171
$9.79
$5.39M
MVA Investors, LLC
2 Jul 2024
See remarks
Sell
95,000
$8.68
$824.60K
MVA Investors, LLC
1 Jul 2024
See remarks
Sell
110,731
$8.87
$982.18K
MVA Investors, LLC
28 Jun 2024
See remarks
Sell
29,000
$8.57
$248.53K
MVA Investors, LLC
7 Jun 2024
See remarks
Sell
77,000
$6.88
$529.76K
MVA Investors, LLC
6 Jun 2024
See remarks
Sell
63,000
$7.24
$456.12K
Lesley Ann Calhoun
5 Jun 2024
Director
Sold on a plan
5,000
$7.21
$36.04K
MVA Investors, LLC
3 May 2024
See remarks
Sell
indirect
60,000
$7.61
$456.60K
MVA Investors, LLC
2 May 2024
See remarks
Sell
indirect
75,000
$7.56
$567.00K
MVA Investors, LLC
1 May 2024
See remarks
Sell
indirect
75,000
$7.43
$557.25K
Third Rock Ventures IV, L.P.
20 Feb 2024
10% owner
Sell
162,500
$12.00
$1.95M
Adam Crystal
7 Feb 2024
See Remarks
Sell
4,083
$12.62
$51.53K
Daniella Beckman
7 Feb 2024
Chief Financial Officer
Sell
1,817
$12.62
$22.93K
Douglas Barry
7 Feb 2024
General Counsel
Sell
1,354
$12.62
$17.09K
Barbara Weber
7 Feb 2024
Chief Executive Officer
Sell
4,457
$12.62
$56.25K
Adam Crystal
6 Feb 2024
See Remarks
Sell
4,288
$12.56
$53.87K
Daniella Beckman
6 Feb 2024
Chief Financial Officer
Sell
1,908
$12.56
$23.97K
Douglas Barry
6 Feb 2024
General Counsel
Sell
1,422
$12.56
$17.86K
Barbara Weber
6 Feb 2024
Chief Executive Officer
Sell
4,681
$12.56
$58.81K
Adam Crystal
1 Nov 2023
See Remarks
Sell
7,507
$8.39
$62.99K
Boxer Capital, LLC
16 Oct 2023
See remarks
Buy
500,000
$6.84
$3.42M
Boxer Capital, LLC
13 Oct 2023
See remarks
Buy
750,000
$7.07
$5.30M
Boxer Capital, LLC
9 Oct 2023
See remarks
Sell
175,000
$9.97
$1.74M
Boxer Capital, LLC
9 Oct 2023
See remarks
Sell
indirect
50,000
$9.91
$495.50K
Boxer Capital, LLC
11 Aug 2023
See remarks
Buy
indirect
475,000
$5.15
$2.45M
Boxer Capital, LLC
13 Oct 2022
10% owner
Buy
70,000
$4.65
$325.23K
Boxer Capital, LLC
12 Oct 2022
10% owner
Buy
50,000
$4.43
$221.64K
Boxer Capital, LLC
11 Oct 2022
10% owner
Buy
117,000
$4.25
$497.71K
Boxer Capital, LLC
6 Oct 2022
10% owner
Buy
70,394
$4.06
$286.07K
Boxer Capital, LLC
5 Oct 2022
10% owner
Buy
40,500
$3.84
$155.41K
Boxer Capital, LLC
5 Oct 2022
10% owner
Buy
45,500
$3.93
$178.64K
Boxer Capital, LLC
4 Oct 2022
10% owner
Buy
25,606
$3.67
$93.98K
BCTG Holdings, LLC
20 Nov 2020
10% owner
Sell
2,500
$0.01
$15.00
BCTG Holdings, LLC
20 Nov 2020
10% owner
Sell
2,500
$0.01
$15.00
BCTG Holdings, LLC
8 Sep 2020
10% owner
Buy
533,500
$10.00
$5.34M
