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Stocks · Health care · Pharmaceutical Preparations

AGIOS PHARMACEUTICALS, INC.

AGIO Clue Score43
United States Fiscal year ends December CIK 0001439222
$31.81 -0.34% Close, 9 Oct 2026
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Price $31.81 −28.21% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue69.9Operating income−201.0Net income−198.5Fiscal year 2017Revenue43.0 −38.5%Operating income−320.8Net income−314.7Fiscal year 2018Revenue94.4 +119.4%Operating income−362.5Net income−346.0Fiscal year 2019Revenue117.9 +24.9%Operating income−316.3Net income−411.5EPS, diluted−6.86Fiscal year 2020Revenue0.0 −100.0%Operating income−335.9Net income−327.4EPS, diluted−4.74Fiscal year 2021Revenue0.0Operating income−378.4Net income1,604.7EPS, diluted26.55Fiscal year 2022Revenue14.2Operating income−389.0Net income−231.8 −114.4%EPS, diluted−4.23 −115.9%Fiscal year 2023Revenue26.8 +88.4%Operating income−391.5Net income−352.1EPS, diluted−6.33Fiscal year 2024Revenue36.5 +36.1%Operating income−425.7Net income673.7EPS, diluted11.64Fiscal year 2025Revenue54.0 +48.0%Operating income−472.1Net income−412.8 −161.3%EPS, diluted−7.12 −161.2%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 69.9 43.0 94.4 117.9 0.0 0.0 14.2 26.8 36.5 54.0
Growth −38.5% +119.4% +24.9% −100.0% +88.4% +36.1% +48.0%
Operating income −201.0 −320.8 −362.5 −316.3 −335.9 −378.4 −389.0 −391.5 −425.7 −472.1
Net income −198.5 −314.7 −346.0 −411.5 −327.4 1,604.7 −231.8 −352.1 673.7 −412.8
Growth −114.4% −161.3%
EPS, diluted n/a n/a n/a −6.86 −4.74 26.55 −4.23 −6.33 11.64 −7.12
Growth −115.9% −161.2%

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Operating margin−287.6%Net margin−284.0%Free cash flow margin41.0%Fiscal year 2017Operating margin−745.8%Net margin−731.6%Free cash flow margin−673.9%Fiscal year 2018Operating margin−384.0%Net margin−366.6%Free cash flow margin−329.9%Fiscal year 2019Operating margin−268.2%Net margin−349.0%Free cash flow margin−324.5%Fiscal year 2020Fiscal year 2021Fiscal year 2022Operating margin−2,732.1%Net margin−1,627.8%Free cash flow margin−2,207.6%Fiscal year 2023Operating margin−1,459.5%Net margin−1,312.6%Free cash flow margin−1,107.5%Fiscal year 2024Operating margin−1,166.5%Net margin1,845.9%Free cash flow margin−1,072.7%Fiscal year 2025Operating margin−873.9%Net margin−764.0%Free cash flow margin−698.3%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin −287.6% −745.8% −384.0% −268.2% n/a n/a −2,732.1% −1,459.5% −1,166.5% −873.9%
Net margin −284.0% −731.6% −366.6% −349.0% n/a n/a −1,627.8% −1,312.6% 1,845.9% −764.0%
Free cash flow margin 41.0% −673.9% −329.9% −324.5% n/a n/a −2,207.6% −1,107.5% −1,072.7% −698.3%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow38.6Capital expenditure−9.9Free cash flow28.6Fiscal year 2017Operating cash flow−285.2Capital expenditure−4.6Free cash flow−289.9 −1,111.8%Fiscal year 2018Operating cash flow−304.4Capital expenditure−7.0Free cash flow−311.4Fiscal year 2019Operating cash flow−370.6Capital expenditure−12.0Free cash flow−382.7Fiscal year 2020Operating cash flow−290.8Capital expenditure−14.1Free cash flow−304.9Fiscal year 2021Operating cash flow−407.3Capital expenditure−5.7Free cash flow−413.1Fiscal year 2022Operating cash flow−309.5Capital expenditure−4.9Free cash flow−314.4Fiscal year 2023Operating cash flow−296.1Capital expenditure−1.0Free cash flow−297.1Fiscal year 2024Operating cash flow−389.8Capital expenditure−1.7Free cash flow−391.5Fiscal year 2025Operating cash flow−373.0Capital expenditure−4.3Free cash flow−377.3
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow 38.6 −285.2 −304.4 −370.6 −290.8 −407.3 −309.5 −296.1 −389.8 −373.0
Capital expenditure −9.9 −4.6 −7.0 −12.0 −14.1 −5.7 −4.9 −1.0 −1.7 −4.3
Free cash flow 28.6 −289.9 −311.4 −382.7 −304.9 −413.1 −314.4 −297.1 −391.5 −377.3
Growth −1,111.8%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2016Cash160.8Shareholders’ equity358.6Fiscal year 2017Cash102.7Shareholders’ equity375.5Fiscal year 2018Cash70.5Shareholders’ equity687.5Fiscal year 2019Cash80.9Shareholders’ equity640.5Fiscal year 2020Cash127.4Shareholders’ equity399.5Fiscal year 2021Cash203.1Shareholders’ equity1,292.0Fiscal year 2022Cash139.3Shareholders’ equity1,100.8Fiscal year 2023Cash88.2Shareholders’ equity811.0Fiscal year 2024Cash76.2Shareholders’ equity1,541.0Fiscal year 2025Cash89.1Shareholders’ equity1,193.1
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 160.8 102.7 70.5 80.9 127.4 203.1 139.3 88.2 76.2 89.1
Shareholders’ equity 358.6 375.5 687.5 640.5 399.5 1,292.0 1,100.8 811.0 1,541.0 1,193.1

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
−287.6% −745.8% −384.0% −268.2% n/a n/a −2,732.1% −1,459.5% −1,166.5% −873.9%
−284.0% −731.6% −366.6% −255.6% n/a n/a −1,627.8% −1,312.6% 1,967.1% −765.9%
−284.0% −731.6% −366.6% −349.0% n/a n/a −1,627.8% −1,312.6% 1,845.9% −764.0%
41.0% −673.9% −329.9% −324.5% n/a n/a −2,207.6% −1,107.5% −1,072.7% −698.3%
Spending
315.0% 680.5% 361.6% 181.7% n/a n/a 1,965.7% 1,101.8% 825.5% 628.4%
72.6% 165.4% 120.9% 86.5% n/a n/a 854.4% 447.0% 429.6% 333.7%
14.2% 10.8% 7.4% 10.2% n/a n/a 34.3% 3.7% 4.6% 8.0%
n/a n/a n/a n/a n/a n/a n/a n/a 6.2% n/a
Returns
−55.3% −83.8% −50.3% −64.2% −81.9% 124.2% −21.1% −43.4% 43.7% −34.6%
−32.1% −51.2% −40.3% −46.2% −38.4% 111.6% −18.7% −37.6% 40.5% −31.8%
Balance and payout
42.1% 38.9% 19.9% 28.1% 53.2% 10.1% 11.1% 13.5% 7.3% 8.0%