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Stocks · Health care · Biological Products, (No Diagnostic Substances)

BIOCRYST PHARMACEUTICALS INC

BCRX Clue Score70
United States Fiscal year ends December CIK 0000882796
$8.55 +3.14% Close, 9 Oct 2026
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Price $8.55 −40.71% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue26.4Operating income−48.6Net income−55.1Fiscal year 2017Revenue25.2 −4.4%Operating income−57.4Net income−65.8Fiscal year 2018Revenue20.7 −18.0%Operating income−94.2Net income−101.3Fiscal year 2019Revenue48.8 +136.5%Operating income−99.5Net income−108.9Fiscal year 2020Revenue17.8 −63.5%Operating income−174.8Net income−182.8EPS, diluted−1.09Fiscal year 2021Revenue157.2 +782.4%Operating income−177.7Net income−184.1EPS, diluted−1.03Fiscal year 2022Revenue270.8 +72.3%Operating income−148.4Net income−247.1EPS, diluted−1.33Fiscal year 2023Revenue331.4 +22.4%Operating income−103.7Net income−226.5EPS, diluted−1.18Fiscal year 2024Revenue450.7 +36.0%Operating income−2.5Net income−88.9EPS, diluted−0.43Fiscal year 2025Revenue874.8 +94.1%Operating income341.0Net income263.9EPS, diluted1.21
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 26.4 25.2 20.7 48.8 17.8 157.2 270.8 331.4 450.7 874.8
Growth −4.4% −18.0% +136.5% −63.5% +782.4% +72.3% +22.4% +36.0% +94.1%
Operating income −48.6 −57.4 −94.2 −99.5 −174.8 −177.7 −148.4 −103.7 −2.5 341.0
Net income −55.1 −65.8 −101.3 −108.9 −182.8 −184.1 −247.1 −226.5 −88.9 263.9
Growth
EPS, diluted n/a n/a n/a n/a −1.09 −1.03 −1.33 −1.18 −0.43 1.21
Growth

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Operating margin−184.4%Net margin−209.3%Free cash flow margin−222.8%Fiscal year 2017Operating margin−227.9%Net margin−261.2%Free cash flow margin−164.7%Fiscal year 2018Operating margin−456.2%Net margin−490.3%Free cash flow margin−450.0%Fiscal year 2019Operating margin−203.7%Net margin−223.0%Free cash flow margin−184.1%Fiscal year 2020Operating margin−981.1%Net margin−1,026.4%Free cash flow margin−761.4%Fiscal year 2021Operating margin−113.1%Net margin−117.1%Free cash flow margin−92.0%Fiscal year 2022Operating margin−54.8%Net margin−91.2%Free cash flow margin−60.3%Fiscal year 2023Operating margin−31.3%Net margin−68.4%Free cash flow margin−29.4%Fiscal year 2024Operating margin−0.6%Net margin−19.7%Free cash flow margin−11.8%Fiscal year 2025Operating margin39.0%Net margin30.2%Free cash flow margin39.4%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin −184.4% −227.9% −456.2% −203.7% −981.1% −113.1% −54.8% −31.3% −0.6% 39.0%
Net margin −209.3% −261.2% −490.3% −223.0% −1,026.4% −117.1% −91.2% −68.4% −19.7% 30.2%
Free cash flow margin −222.8% −164.7% −450.0% −184.1% −761.4% −92.0% −60.3% −29.4% −11.8% 39.4%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−53.4Capital expenditure−5.3Free cash flow−58.7Fiscal year 2017Operating cash flow−41.1Capital expenditure−0.3Free cash flow−41.5Fiscal year 2018Operating cash flow−92.6Capital expenditure−0.4Free cash flow−92.9Fiscal year 2019Operating cash flow−89.6Capital expenditure−0.3Free cash flow−89.9Fiscal year 2020Operating cash flow−135.1Capital expenditure−0.5Free cash flow−135.6Fiscal year 2021Operating cash flow−142.2Capital expenditure−2.4Free cash flow−144.5Fiscal year 2022Operating cash flow−161.9Capital expenditure−1.4Free cash flow−163.2Fiscal year 2023Operating cash flow−95.1Capital expenditure−2.2Free cash flow−97.3Fiscal year 2024Operating cash flow−52.0Capital expenditure−1.1Free cash flow−53.1Fiscal year 2025Operating cash flow347.4Capital expenditure−2.5Free cash flow344.9
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −53.4 −41.1 −92.6 −89.6 −135.1 −142.2 −161.9 −95.1 −52.0 347.4
Capital expenditure −5.3 −0.3 −0.4 −0.3 −0.5 −2.4 −1.4 −2.2 −1.1 −2.5
Free cash flow −58.7 −41.5 −92.9 −89.9 −135.6 −144.5 −163.2 −97.3 −53.1 344.9
Growth

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash22.1Total debt23.0Net cash (debt)−0.9Shareholders’ equity1.6Debt to equity14.58Fiscal year 2017Cash50.3Total debt23.0Net cash (debt)27.3Shareholders’ equity83.8Debt to equity0.27Fiscal year 2018Cash26.7Total debt30.0Net cash (debt)−3.3Shareholders’ equity49.2Debt to equity0.61Fiscal year 2019Cash114.2Total debt0.0Net cash (debt)114.2Shareholders’ equity38.3Debt to equity0.00Fiscal year 2020Cash272.1Total debt119.7Net cash (debt)152.4Shareholders’ equity−19.3Fiscal year 2021Cash504.4Total debt136.1Net cash (debt)368.3Shareholders’ equity−107.0Fiscal year 2022Cash304.8Total debt231.6Net cash (debt)73.1Shareholders’ equity−294.6Fiscal year 2023Cash110.6Total debt303.2Net cash (debt)−192.6Shareholders’ equity−455.5Fiscal year 2024Cash104.7Total debt314.9Net cash (debt)−210.2Shareholders’ equity−475.9Fiscal year 2025Cash89.7Total debt0.0Net cash (debt)89.7Shareholders’ equity−119.2
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 22.1 50.3 26.7 114.2 272.1 504.4 304.8 110.6 104.7 89.7
Total debt 23.0 23.0 30.0 0.0 119.7 136.1 231.6 303.2 314.9 0.0
Net cash (debt) −0.9 27.3 −3.3 114.2 152.4 368.3 73.1 −192.6 −210.2 89.7
Shareholders’ equity 1.6 83.8 49.2 38.3 −19.3 −107.0 −294.6 −455.5 −475.9 −119.2
Debt to equity 14.58 0.27 0.61 0.00 n/a n/a n/a n/a n/a n/a

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
−184.4% −227.9% −456.2% −203.7% −981.1% −113.1% −54.8% −31.3% −0.6% 39.0%
n/a n/a n/a −223.0% −1,026.4% −115.7% −90.2% −68.3% −19.3% 30.6%
−209.3% −261.2% −490.3% −223.0% −1,026.4% −117.1% −91.2% −68.4% −19.7% 30.2%
−222.8% −164.7% −450.0% −184.1% −761.4% −92.0% −60.3% −29.4% −11.8% 39.4%
Spending
231.5% 265.9% 411.0% 219.2% 690.3% 132.9% 93.5% 65.3% 38.7% 19.0%
42.7% 55.3% 142.9% 76.0% 381.4% 75.6% 58.8% 64.6% 59.1% 39.9%
20.0% 1.3% 1.8% 0.7% 2.9% 1.5% 0.5% 0.7% 0.2% 0.3%
n/a n/a n/a n/a n/a n/a n/a n/a n/a 1.3%
Returns
−3,494.6% −78.5% −205.7% −284.7% n/a n/a n/a n/a n/a n/a
−61.4% −36.9% −69.0% −62.1% −54.6% −31.3% −44.9% −43.8% −18.1% 51.3%
Balance and payout
14.58 0.27 0.61 0.00 n/a n/a n/a n/a n/a n/a
n/a n/a n/a n/a n/a n/a n/a 188.1% 197.0% 123.2%