Stocks · Health care · Biological Products, (No Diagnostic Substances)

CRISPR Therapeutics AG

CRSP Clue Score37
Switzerland Fiscal year ends December CIK 0001674416
$53.39 +5.85% Close, 9 Oct 2026
Price $53.39 −46.95% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 19 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue5.2Operating income−68.1Net income−23.2Fiscal year 2017Revenue41.0 +693.9%Operating income−64.6Net income−68.4EPS, diluted−1.71Fiscal year 2018Revenue3.1 −92.4%Operating income−158.9Net income−165.0EPS, diluted−3.44Fiscal year 2019Revenue289.6 +9,169.8%Operating income46.7Net income66.9EPS, diluted1.17Fiscal year 2020Revenue0.7 −99.8%Operating income−354.4Net income−348.9 −621.8%EPS, diluted−5.29 −552.1%Fiscal year 2021Revenue915.0 +127,154.9%Operating income373.5Net income377.7EPS, diluted4.70Fiscal year 2022Revenue1.2 −99.9%Operating income−673.2Net income−650.2 −272.2%EPS, diluted−8.36 −277.9%Fiscal year 2023Revenue371.2 +30,885.5%Operating income−222.5Net income−153.6EPS, diluted−1.94Fiscal year 2024Revenue37.3 −89.9%Operating income−466.6Net income−366.3EPS, diluted−4.34Fiscal year 2025Revenue3.5 −90.6%Operating income−664.6Net income−581.6EPS, diluted−6.47
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 5.2 41.0 3.1 289.6 0.7 915.0 1.2 371.2 37.3 3.5
Growth +693.9% −92.4% +9,169.8% −99.8% +127,154.9% −99.9% +30,885.5% −89.9% −90.6%
Operating income −68.1 −64.6 −158.9 46.7 −354.4 373.5 −673.2 −222.5 −466.6 −664.6
Net income −23.2 −68.4 −165.0 66.9 −348.9 377.7 −650.2 −153.6 −366.3 −581.6
Growth −621.8% −272.2%
EPS, diluted n/a −1.71 −3.44 1.17 −5.29 4.70 −8.36 −1.94 −4.34 −6.47
Growth −552.1% −277.9%

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Operating margin−1,319.3%Net margin−448.8%Free cash flow margin−1,082.0%Fiscal year 2017Operating margin−157.7%Net margin−166.7%Free cash flow margin−190.0%Fiscal year 2018Operating margin−5,087.8%Net margin−5,281.1%Free cash flow margin−3,169.4%Fiscal year 2019Operating margin16.1%Net margin23.1%Free cash flow margin17.3%Fiscal year 2020Operating margin−49,295.5%Net margin−48,520.9%Free cash flow margin−35,705.7%Fiscal year 2021Operating margin40.8%Net margin41.3%Free cash flow margin50.0%Fiscal year 2022Operating margin−56,190.4%Net margin−54,271.7%Free cash flow margin−44,484.9%Fiscal year 2023Operating margin−60.0%Net margin−41.4%Free cash flow margin−72.7%Fiscal year 2024Operating margin−1,250.4%Net margin−981.5%Free cash flow margin−387.7%Fiscal year 2025Operating margin−18,933.6%Net margin−16,569.8%Free cash flow margin−9,855.5%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin −1,319.3% −157.7% −5,087.8% 16.1% −49,295.5% 40.8% −56,190.4% −60.0% −1,250.4% −18,933.6%
Net margin −448.8% −166.7% −5,281.1% 23.1% −48,520.9% 41.3% −54,271.7% −41.4% −981.5% −16,569.8%
Free cash flow margin −1,082.0% −190.0% −3,169.4% 17.3% −35,705.7% 50.0% −44,484.9% −72.7% −387.7% −9,855.5%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−52.9Capital expenditure−3.0Free cash flow−55.9Fiscal year 2017Operating cash flow−70.1Capital expenditure−7.8Free cash flow−77.9Fiscal year 2018Operating cash flow−96.2Capital expenditure−2.8Free cash flow−99.0Buybacks−0.1Fiscal year 2019Operating cash flow56.7Capital expenditure−6.7Free cash flow50.0Fiscal year 2020Operating cash flow−238.4Capital expenditure−18.4Free cash flow−256.7 −613.5%Fiscal year 2021Operating cash flow539.0Capital expenditure−81.7Free cash flow457.3Fiscal year 2022Operating cash flow−495.7Capital expenditure−37.2Free cash flow−532.9 −216.5%Fiscal year 2023Operating cash flow−260.4Capital expenditure−9.5Free cash flow−269.8Fiscal year 2024Operating cash flow−142.8Capital expenditure−1.9Free cash flow−144.7Fiscal year 2025Operating cash flow−345.0Capital expenditure−0.9Free cash flow−345.9
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −52.9 −70.1 −96.2 56.7 −238.4 539.0 −495.7 −260.4 −142.8 −345.0
Capital expenditure −3.0 −7.8 −2.8 −6.7 −18.4 −81.7 −37.2 −9.5 −1.9 −0.9
Free cash flow −55.9 −77.9 −99.0 50.0 −256.7 457.3 −532.9 −269.8 −144.7 −345.9
Growth −613.5% −216.5%
Buybacks n/a n/a −0.1 n/a n/a n/a n/a n/a n/a n/a

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash315.5Shareholders’ equity232.8Fiscal year 2017Cash239.8Shareholders’ equity187.8Fiscal year 2018Cash456.6Shareholders’ equity392.2Fiscal year 2019Cash943.8Shareholders’ equity939.4Fiscal year 2020Cash1,168.6Shareholders’ equity1,664.2Fiscal year 2021Cash923.0Shareholders’ equity2,399.5Fiscal year 2022Cash211.9Shareholders’ equity1,875.5Fiscal year 2023Cash389.5Shareholders’ equity1,882.8Fiscal year 2024Cash298.3Shareholders’ equity1,932.1Fiscal year 2025Cash347.6Total debt0.0Net cash (debt)347.6Shareholders’ equity1,921.8Debt to equity0.00
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 315.5 239.8 456.6 943.8 1,168.6 923.0 211.9 389.5 298.3 347.6
Total debt n/a n/a n/a n/a n/a n/a n/a n/a n/a 0.0
Net cash (debt) n/a n/a n/a n/a n/a n/a n/a n/a n/a 347.6
Shareholders’ equity 232.8 187.8 392.2 939.4 1,664.2 2,399.5 1,875.5 1,882.8 1,932.1 1,921.8
Debt to equity n/a n/a n/a n/a n/a n/a n/a n/a n/a 0.00

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Cash flow

In millions of USD, except per-share figures; shares in millions. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Operations
−52.9 −70.1 −96.2 56.7 −238.4 539.0 −495.7 −260.4 −142.8 −345.0
Growth −520.6% −192.0%
0.9 3.0 3.5 4.7 9.2 18.0 24.2 19.8 19.3 19.5
Investment
−3.0 −7.8 −2.8 −6.7 −18.4 −81.7 −37.2 −9.5 −1.9 −0.9
calc −55.9 −77.9 −99.0 50.0 −256.7 457.3 −532.9 −269.8 −144.7 −345.9
Growth −613.5% −216.5%
calc n/a −1.94 −2.06 0.88 −3.89 5.69 −6.85 −3.41 −1.71 −3.85
31.9 −8.3 −2.8 1.3 −541.2 −1,035.4 −258.7 374.6 −280.5 −31.8
Financing
183.2 2.6 315.9 431.0 1,016.2 250.9 38.6 62.7 332.0 426.0
n/a n/a −0.1 n/a n/a n/a n/a n/a n/a n/a

Lines marked calc are worked out here from filed figures; point at one for how. Capital expenditure, dividends and buybacks are shown as money out, so negative.