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Stocks · Health care · Pharmaceutical Preparations

Fulcrum Therapeutics, Inc.

FULC Clue Score33
United States Fiscal year ends December CIK 0001680581
$3.77 +0.53% Close, 9 Oct 2026
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Price $3.77 −86.37% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 18 Jul 2019. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2018Operating income−33.5Net income−32.6Fiscal year 2019Operating income−84.2Net income−82.7Fiscal year 2020Revenue8.8Operating income−71.6Net income−70.8EPS, diluted−2.79Fiscal year 2021Revenue19.2 +117.2%Operating income−81.1Net income−80.8EPS, diluted−2.29Fiscal year 2022Revenue6.3 −66.9%Operating income−112.6Net income−109.9EPS, diluted−2.44Fiscal year 2023Revenue2.8 −55.8%Operating income−110.7Net income−97.3EPS, diluted−1.59Fiscal year 2024Revenue80.0 +2,752.0%Operating income−21.9Net income−9.7EPS, diluted−0.16Fiscal year 2025Revenue0.0 −100.0%Operating income−84.8Net income−74.9EPS, diluted−1.18
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue n/a n/a 8.8 19.2 6.3 2.8 80.0 0.0
Growth +117.2% −66.9% −55.8% +2,752.0% −100.0%
Operating income −33.5 −84.2 −71.6 −81.1 −112.6 −110.7 −21.9 −84.8
Net income −32.6 −82.7 −70.8 −80.8 −109.9 −97.3 −9.7 −74.9
Growth
EPS, diluted n/a n/a −2.79 −2.29 −2.44 −1.59 −0.16 −1.18
Growth

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2018Fiscal year 2019Fiscal year 2020Operating margin−811.6%Net margin−802.7%Free cash flow margin−623.3%Fiscal year 2021Operating margin−423.0%Net margin−421.9%Free cash flow margin−418.5%Fiscal year 2022Operating margin−1,774.9%Net margin−1,732.4%Free cash flow margin−1,561.2%Fiscal year 2023Operating margin−3,945.2%Net margin−3,470.1%Free cash flow margin−3,261.1%Fiscal year 2024Operating margin−27.4%Net margin−12.2%Free cash flow margin−3.1%Fiscal year 2025
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin n/a n/a −811.6% −423.0% −1,774.9% −3,945.2% −27.4% n/a
Net margin n/a n/a −802.7% −421.9% −1,732.4% −3,470.1% −12.2% n/a
Free cash flow margin n/a n/a −623.3% −418.5% −1,561.2% −3,261.1% −3.1% n/a

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2018Operating cash flow−22.6Capital expenditure−9.0Free cash flow−31.5Fiscal year 2019Operating cash flow−39.5Capital expenditure−0.9Free cash flow−40.3Fiscal year 2020Operating cash flow−53.7Capital expenditure−1.3Free cash flow−55.0Fiscal year 2021Operating cash flow−78.5Capital expenditure−1.7Free cash flow−80.2Fiscal year 2022Operating cash flow−97.1Capital expenditure−2.0Free cash flow−99.0Fiscal year 2023Operating cash flow−91.0Capital expenditure−0.5Free cash flow−91.5Fiscal year 2024Operating cash flow−2.2Capital expenditure−0.3Free cash flow−2.5Fiscal year 2025Operating cash flow−60.1Capital expenditure−0.3Free cash flow−60.4
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −22.6 −39.5 −53.7 −78.5 −97.1 −91.0 −2.2 −60.1
Capital expenditure −9.0 −0.9 −1.3 −1.7 −2.0 −0.5 −0.3 −0.3
Free cash flow −31.5 −40.3 −55.0 −80.2 −99.0 −91.5 −2.5 −60.4
Growth

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2018Cash72.8Shareholders’ equity−63.7Fiscal year 2019Cash96.7Shareholders’ equity87.2Fiscal year 2020Cash57.1Shareholders’ equity95.2Fiscal year 2021Cash35.4Shareholders’ equity211.5Fiscal year 2022Cash35.1Shareholders’ equity198.9Fiscal year 2023Cash25.6Shareholders’ equity235.2Fiscal year 2024Cash58.2Shareholders’ equity243.0Fiscal year 2025Cash197.5Shareholders’ equity349.0
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 72.8 96.7 57.1 35.4 35.1 25.6 58.2 197.5
Shareholders’ equity −63.7 87.2 95.2 211.5 198.9 235.2 243.0 349.0

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
n/a n/a −811.6% −423.0% −1,774.9% −3,945.2% −27.4% n/a
n/a n/a −802.7% −421.9% −1,732.4% −3,470.1% −12.2% n/a
n/a n/a −623.3% −418.5% −1,561.2% −3,261.1% −3.1% n/a
Spending
n/a n/a 669.2% 363.7% 1,210.7% 2,559.8% 79.2% n/a
n/a n/a 242.5% 159.2% 657.4% 1,485.5% 45.6% n/a
n/a n/a 15.2% 8.9% 31.0% 18.1% 0.3% n/a
Returns
n/a −94.9% −74.4% −38.2% −55.2% −41.4% −4.0% −21.5%
−38.0% −74.9% −54.7% −34.4% −48.5% −37.8% −3.7% −20.4%
Balance and payout
11.4% 21.1% 26.5% 10.0% 12.2% 8.7% 6.8% 4.7%