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Stocks · Health care · Pharmaceutical Preparations

LEXICON PHARMACEUTICALS, INC.

LXRX Clue Score48
United States Fiscal year ends December CIK 0001062822
$1.68 -4.55% Close, 9 Oct 2026
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Price $1.68 −70.78% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue0.0Operating income−127.2Net income−131.4Fiscal year 2017Revenue15.9Operating income−130.6Net income−123.0EPS, diluted−1.17Fiscal year 2018Revenue26.6 +67.3%Operating income−103.3Net income−120.5EPS, diluted−1.14Fiscal year 2019Revenue32.3 +21.6%Operating income141.4Net income130.1EPS, diluted1.16Fiscal year 2020Revenue23.4 −27.6%Operating income−47.8Net income−58.6 −145.0%EPS, diluted−0.53 −145.7%Fiscal year 2021Revenue0.0 −100.0%Operating income−87.1Net income−87.8EPS, diluted−0.60Fiscal year 2022Revenue0.0Operating income−100.8Net income−101.9EPS, diluted−0.62Fiscal year 2023Revenue1.1Operating income−171.8Net income−177.1EPS, diluted−0.80Fiscal year 2024Revenue6.0 +440.6%Operating income−197.1Net income−200.4EPS, diluted−0.63Fiscal year 2025Revenue49.8 +729.9%Operating income−48.9Net income−50.3EPS, diluted−0.14
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 0.0 15.9 26.6 32.3 23.4 0.0 0.0 1.1 6.0 49.8
Growth +67.3% +21.6% −27.6% −100.0% +440.6% +729.9%
Operating income −127.2 −130.6 −103.3 141.4 −47.8 −87.1 −100.8 −171.8 −197.1 −48.9
Net income −131.4 −123.0 −120.5 130.1 −58.6 −87.8 −101.9 −177.1 −200.4 −50.3
Growth −145.0%
EPS, diluted n/a −1.17 −1.14 1.16 −0.53 −0.60 −0.62 −0.80 −0.63 −0.14
Growth −145.7%

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Fiscal year 2017Operating margin−822.1%Net margin−774.0%Free cash flow margin−1,168.2%Fiscal year 2018Operating margin−388.5%Net margin−453.5%Free cash flow margin−559.4%Fiscal year 2019Operating margin437.5%Net margin402.5%Free cash flow margin351.8%Fiscal year 2020Operating margin−204.2%Net margin−250.3%Free cash flow margin−611.2%Fiscal year 2021Fiscal year 2022Fiscal year 2023Operating margin−15,473.0%Net margin−15,956.7%Free cash flow margin−14,627.7%Fiscal year 2024Operating margin−3,284.7%Net margin−3,339.5%Free cash flow margin−2,996.4%Fiscal year 2025Operating margin−98.2%Net margin−101.1%Free cash flow margin−136.2%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin n/a −822.1% −388.5% 437.5% −204.2% n/a n/a −15,473.0% −3,284.7% −98.2%
Net margin n/a −774.0% −453.5% 402.5% −250.3% n/a n/a −15,956.7% −3,339.5% −101.1%
Free cash flow margin n/a −1,168.2% −559.4% 351.8% −611.2% n/a n/a −14,627.7% −2,996.4% −136.2%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−175.6Capital expenditure−0.2Free cash flow−175.9Buybacks−0.6Fiscal year 2017Operating cash flow−185.4Capital expenditure−0.2Free cash flow−185.6Buybacks−1.7Fiscal year 2018Operating cash flow−148.6Capital expenditure−0.1Free cash flow−148.7Buybacks−1.0Fiscal year 2019Operating cash flow113.8Capital expenditure−0.1Free cash flow113.7Buybacks−0.9Fiscal year 2020Operating cash flow−143.0Capital expenditure−0.1Free cash flow−143.1 −225.8%Buybacks−1.0Fiscal year 2021Operating cash flow−87.0Capital expenditure−1.2Free cash flow−88.2Buybacks−2.7Fiscal year 2022Operating cash flow−88.9Capital expenditure−1.3Free cash flow−90.2Buybacks−0.9Fiscal year 2023Operating cash flow−161.9Capital expenditure−0.5Free cash flow−162.4Buybacks−0.8Fiscal year 2024Operating cash flow−178.8Capital expenditure−1.0Free cash flow−179.8Buybacks−1.7Fiscal year 2025Operating cash flow−67.9Capital expenditure0.0Free cash flow−67.9
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −175.6 −185.4 −148.6 113.8 −143.0 −87.0 −88.9 −161.9 −178.8 −67.9
Capital expenditure −0.2 −0.2 −0.1 −0.1 −0.1 −1.2 −1.3 −0.5 −1.0 0.0
Free cash flow −175.9 −185.6 −148.7 113.7 −143.1 −88.2 −90.2 −162.4 −179.8 −67.9
Growth −225.8%
Buybacks −0.6 −1.7 −1.0 −0.9 −1.0 −2.7 −0.9 −0.8 −1.7 n/a

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash46.6Total debt101.4Net cash (debt)−54.8Shareholders’ equity167.5Debt to equity0.61Fiscal year 2017Cash61.7Total debt245.7Net cash (debt)−184.0Shareholders’ equity68.3Debt to equity3.60Fiscal year 2018Cash80.4Total debt245.0Net cash (debt)−164.6Shareholders’ equity−26.4Fiscal year 2019Cash36.1Total debt245.2Net cash (debt)−209.1Shareholders’ equity117.1Debt to equity2.09Fiscal year 2020Cash126.3Total debt11.6Net cash (debt)114.6Shareholders’ equity156.4Debt to equity0.07Fiscal year 2021Cash64.1Total debt0.0Net cash (debt)64.1Shareholders’ equity113.6Debt to equity0.00Fiscal year 2022Cash46.3Total debt48.6Net cash (debt)−2.2Shareholders’ equity117.1Debt to equity0.41Fiscal year 2023Cash22.5Total debt99.5Net cash (debt)−77.0Shareholders’ equity93.1Debt to equity1.07Fiscal year 2024Cash66.7Total debt100.3Net cash (debt)−33.6Shareholders’ equity146.0Debt to equity0.69Fiscal year 2025Cash34.3Total debt54.0Net cash (debt)−19.7Shareholders’ equity107.5Debt to equity0.50
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 46.6 61.7 80.4 36.1 126.3 64.1 46.3 22.5 66.7 34.3
Total debt 101.4 245.7 245.0 245.2 11.6 0.0 48.6 99.5 100.3 54.0
Net cash (debt) −54.8 −184.0 −164.6 −209.1 114.6 64.1 −2.2 −77.0 −33.6 −19.7
Shareholders’ equity 167.5 68.3 −26.4 117.1 156.4 113.6 117.1 93.1 146.0 107.5
Debt to equity 0.61 3.60 n/a 2.09 0.07 0.00 0.41 1.07 0.69 0.50

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Income statement

In millions of USD, except per-share figures; shares in millions. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Revenue and profit
0.0 15.9 26.6 32.3 23.4 0.0 0.0 1.1 6.0 49.8
Growth +67.3% +21.6% −27.6% −100.0% +440.6% +729.9%
0.0 1.9 2.5 3.2 1.9 0.0 0.0 0.1 0.6 0.3
164.0 152.2 100.2 91.9 153.6 55.0 52.8 58.9 84.5 61.1
43.2 66.1 63.8 56.8 47.2 32.3 48.1 114.0 143.1 37.3
−127.2 −130.6 −103.3 141.4 −47.8 −87.1 −100.8 −171.8 −197.1 −48.9
Growth −133.8%
−131.4 −135.7 −120.5 124.1 −58.6 −87.8 n/a n/a n/a n/a
0.0 n/a n/a n/a n/a 0.0 0.0 0.0 0.0 n/a
−131.4 −123.0 −120.5 130.1 −58.6 −87.8 −101.9 −177.1 −200.4 −50.3
Growth −145.0%
Per share
n/a −1.17 −1.14 1.23 −0.53 −0.60 −0.62 −0.80 −0.63 −0.14
n/a −1.17 −1.14 1.16 −0.53 −0.60 −0.62 −0.80 −0.63 −0.14
Growth −145.7%
n/a n/a n/a n/a n/a 145.7 165.7 221.1 320.0 363.1
n/a 105.2 105.8 116.7 110.8 145.7 165.7 221.1 320.0 363.1
Growth +0.6% +10.3% −5.1% +31.4% +13.8% +33.4% +44.7% +13.4%

Five years in brief

Worked out from the figures above, not from a press release
  • Revenue grew 16.3% a year over five years.
  • The diluted share count rose 227.5% in five years, which is dilution.
  • Operating margin is up 106.0 points on five years ago, at -98.2%.
  • A net loss in 9 of 10 years on file.