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Stocks · Health care · Pharmaceutical Preparations

OPKO HEALTH, INC.

OPK Clue Score33
United States Fiscal year ends December CIK 0000944809
$1.38 +0.73% Close, 9 Oct 2026
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Price $1.38 −63.20% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue1,117.5Operating income−96.6Net income−48.4EPS, diluted−0.10Fiscal year 2017Revenue966.0 −13.6%Operating income−276.4Net income−305.3EPS, diluted−0.55Fiscal year 2018Revenue990.3 +2.5%Operating income−171.2Net income−153.0EPS, diluted−0.27Fiscal year 2019Revenue901.9 −8.9%Operating income−274.1Net income−314.9EPS, diluted−0.53Fiscal year 2020Revenue1,435.4 +59.1%Operating income57.7Net income30.6EPS, diluted0.05Fiscal year 2021Revenue1,774.7 +23.6%Operating income18.8Net income−30.1 −198.6%EPS, diluted−0.05 −200.0%Fiscal year 2022Revenue1,004.2 −43.4%Operating income−226.3Net income−328.4EPS, diluted−0.46Fiscal year 2023Revenue863.5 −14.0%Operating income−157.0Net income−188.9EPS, diluted−0.25Fiscal year 2024Revenue713.1 −17.4%Operating income−152.1Net income−53.2EPS, diluted−0.08Fiscal year 2025Revenue606.9 −14.9%Operating income−117.4Net income−225.7EPS, diluted−0.30
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 1,117.5 966.0 990.3 901.9 1,435.4 1,774.7 1,004.2 863.5 713.1 606.9
Growth −13.6% +2.5% −8.9% +59.1% +23.6% −43.4% −14.0% −17.4% −14.9%
Operating income −96.6 −276.4 −171.2 −274.1 57.7 18.8 −226.3 −157.0 −152.1 −117.4
Net income −48.4 −305.3 −153.0 −314.9 30.6 −30.1 −328.4 −188.9 −53.2 −225.7
Growth −198.6%
EPS, diluted −0.10 −0.55 −0.27 −0.53 0.05 −0.05 −0.46 −0.25 −0.08 −0.30
Growth −200.0%

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Gross marginOperating marginNet margin
Fiscal year 2016Operating margin−8.6%Net margin−4.3%Free cash flow margin1.2%Fiscal year 2017Operating margin−28.6%Net margin−31.6%Free cash flow margin−14.3%Fiscal year 2018Operating margin−17.3%Net margin−15.5%Free cash flow margin−13.8%Fiscal year 2019Operating margin−30.4%Net margin−34.9%Free cash flow margin−20.5%Fiscal year 2020Operating margin4.0%Net margin2.1%Free cash flow margin0.4%Fiscal year 2021Operating margin1.1%Net margin−1.7%Free cash flow margin0.3%Fiscal year 2022Gross margin28.7%Operating margin−22.5%Net margin−32.7%Free cash flow margin−11.9%Fiscal year 2023Gross margin36.8%Operating margin−18.2%Net margin−21.9%Free cash flow margin−5.2%Fiscal year 2024Gross margin30.6%Operating margin−21.3%Net margin−7.5%Free cash flow margin−29.2%Fiscal year 2025Gross margin33.9%Operating margin−19.3%Net margin−37.2%Free cash flow margin−31.4%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Gross margin n/a n/a n/a n/a n/a n/a 28.7% 36.8% 30.6% 33.9%
Operating margin −8.6% −28.6% −17.3% −30.4% 4.0% 1.1% −22.5% −18.2% −21.3% −19.3%
Net margin −4.3% −31.6% −15.5% −34.9% 2.1% −1.7% −32.7% −21.9% −7.5% −37.2%
Free cash flow margin 1.2% −14.3% −13.8% −20.5% 0.4% 0.3% −11.9% −5.2% −29.2% −31.4%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow32.0Capital expenditure−18.5Free cash flow13.5Fiscal year 2017Operating cash flow−92.1Capital expenditure−46.5Free cash flow−138.6 −1,126.8%Fiscal year 2018Operating cash flow−109.1Capital expenditure−27.9Free cash flow−137.0Fiscal year 2019Operating cash flow−172.5Capital expenditure−12.7Free cash flow−185.3Fiscal year 2020Operating cash flow39.5Capital expenditure−33.7Free cash flow5.8Fiscal year 2021Operating cash flow38.3Capital expenditure−32.2Free cash flow6.2 +6.7%Fiscal year 2022Operating cash flow−95.2Capital expenditure−24.6Free cash flow−119.8 −2,037.7%Buybacks0.0Fiscal year 2023Operating cash flow−28.2Capital expenditure−16.3Free cash flow−44.5Buybacks0.0Fiscal year 2024Operating cash flow−183.5Capital expenditure−25.0Free cash flow−208.5Buybacks−90.2Fiscal year 2025Operating cash flow−178.5Capital expenditure−12.3Free cash flow−190.8Buybacks−47.0
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow 32.0 −92.1 −109.1 −172.5 39.5 38.3 −95.2 −28.2 −183.5 −178.5
Capital expenditure −18.5 −46.5 −27.9 −12.7 −33.7 −32.2 −24.6 −16.3 −25.0 −12.3
Free cash flow 13.5 −138.6 −137.0 −185.3 5.8 6.2 −119.8 −44.5 −208.5 −190.8
Growth −1,126.8% +6.7% −2,037.7%
Buybacks n/a n/a n/a n/a n/a n/a 0.0 0.0 −90.2 −47.0

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash168.7Total debt12.7Net cash (debt)156.0Shareholders’ equity2,046.4Debt to equity0.01Fiscal year 2017Cash91.5Total debt13.5Net cash (debt)78.0Shareholders’ equity1,843.6Debt to equity0.01Fiscal year 2018Cash96.5Total debt10.5Net cash (debt)86.0Shareholders’ equity1,791.3Debt to equity0.01Fiscal year 2019Cash85.5Total debt3.9Net cash (debt)81.5Shareholders’ equity1,614.8Debt to equity0.00Fiscal year 2020Cash72.2Total debt3.8Net cash (debt)68.4Shareholders’ equity1,671.6Debt to equity0.00Fiscal year 2021Cash134.7Total debt205.3Net cash (debt)−70.6Shareholders’ equity1,685.1Debt to equity0.12Fiscal year 2022Cash153.2Total debt11.0Net cash (debt)142.2Shareholders’ equity1,561.6Debt to equity0.01Fiscal year 2023Cash95.9Total debt9.7Net cash (debt)86.2Shareholders’ equity1,389.2Debt to equity0.01Fiscal year 2024Cash426.6Total debt440.2Net cash (debt)−13.6Shareholders’ equity1,365.4Debt to equity0.32Fiscal year 2025Cash364.4Total debt346.2Net cash (debt)18.2Shareholders’ equity1,268.0Debt to equity0.27
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 168.7 91.5 96.5 85.5 72.2 134.7 153.2 95.9 426.6 364.4
Total debt 12.7 13.5 10.5 3.9 3.8 205.3 11.0 9.7 440.2 346.2
Net cash (debt) 156.0 78.0 86.0 81.5 68.4 −70.6 142.2 86.2 −13.6 18.2
Shareholders’ equity 2,046.4 1,843.6 1,791.3 1,614.8 1,671.6 1,685.1 1,561.6 1,389.2 1,365.4 1,268.0
Debt to equity 0.01 0.01 0.01 0.00 0.00 0.12 0.01 0.01 0.32 0.27

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
n/a n/a n/a n/a n/a n/a 28.7% 36.8% 30.6% 33.9%
−8.6% −28.6% −17.3% −30.4% 4.0% 1.1% −22.5% −18.2% −21.3% −19.3%
−8.7% −28.1% −17.9% −33.8% 3.4% −0.8% −39.0% −21.3% −1.5% −39.8%
−4.3% −31.6% −15.5% −34.9% 2.1% −1.7% −32.7% −21.9% −7.5% −37.2%
1.2% −14.3% −13.8% −20.5% 0.4% 0.3% −11.9% −5.2% −29.2% −31.4%
Spending
10.2% 13.1% 12.7% 13.1% 5.2% 4.3% 7.4% 10.4% 14.8% 20.4%
36.5% 42.9% 36.2% 38.1% 24.8% 26.4% 37.1% 34.8% 42.7% 36.7%
1.7% 4.8% 2.8% 1.4% 2.3% 1.8% 2.4% 1.9% 3.5% 2.0%
n/a n/a n/a n/a 36.2% n/a n/a n/a n/a n/a
Returns
−2.4% −16.6% −8.5% −19.5% 1.8% −1.8% −21.0% −13.6% −3.9% −17.8%
−1.7% −11.8% −6.2% −13.6% 1.2% −1.3% −15.2% −9.4% −2.4% −11.7%
Balance and payout
0.01 0.01 0.01 0.00 0.00 0.12 0.01 0.01 0.32 0.27
24.4% 28.8% 26.9% 30.1% 32.4% 29.8% 27.9% 30.9% 37.9% 34.4%