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Stocks · Health care · Pharmaceutical Preparations

PUMA BIOTECHNOLOGY, INC.

PBYI Clue Score62
United States Fiscal year ends December CIK 0001401667
$10.29 +3.21% Close, 9 Oct 2026
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Price $10.29 +64.90% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Operating income−276.6Net income−276.0Fiscal year 2017Revenue27.7Operating income−292.4Net income−292.0Fiscal year 2018Revenue251.0 +806.6%Operating income−94.7Net income−113.6Fiscal year 2019Revenue272.3 +8.5%Operating income−39.0Net income−75.6Fiscal year 2020Revenue225.1 −17.3%Operating income−30.4Net income−60.0EPS, diluted−1.52Fiscal year 2021Revenue253.2 +12.5%Operating income1.3Net income−29.1EPS, diluted−0.72Fiscal year 2022Revenue228.0 −9.9%Operating income23.7Net income0.0EPS, diluted0.00Fiscal year 2023Revenue235.6 +3.3%Operating income32.6Net income21.6 +1,079,450.0%EPS, diluted0.45Fiscal year 2024Revenue230.5 −2.2%Operating income31.0Net income30.3 +40.2%EPS, diluted0.62 +37.8%Fiscal year 2025Revenue228.4 −0.9%Operating income37.3Net income31.1 +2.8%EPS, diluted0.61 −1.6%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue n/a 27.7 251.0 272.3 225.1 253.2 228.0 235.6 230.5 228.4
Growth +806.6% +8.5% −17.3% +12.5% −9.9% +3.3% −2.2% −0.9%
Operating income −276.6 −292.4 −94.7 −39.0 −30.4 1.3 23.7 32.6 31.0 37.3
Net income −276.0 −292.0 −113.6 −75.6 −60.0 −29.1 0.0 21.6 30.3 31.1
Growth +1,079,450.0% +40.2% +2.8%
EPS, diluted n/a n/a n/a n/a −1.52 −0.72 0.00 0.45 0.62 0.61
Growth +37.8% −1.6%

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Fiscal year 2017Operating margin−1,056.1%Net margin−1,054.6%Free cash flow margin−624.5%Fiscal year 2018Operating margin−37.7%Net margin−45.3%Free cash flow margin−9.8%Fiscal year 2019Operating margin−14.3%Net margin−27.8%Free cash flow margin8.1%Fiscal year 2020Operating margin−13.5%Net margin−26.7%Free cash flow margin0.3%Fiscal year 2021Operating margin0.5%Net margin−11.5%Free cash flow margin8.2%Fiscal year 2022Operating margin10.4%Net margin0.0%Free cash flow margin−6.9%Fiscal year 2023Operating margin13.9%Net margin9.2%Free cash flow margin11.4%Fiscal year 2024Operating margin13.4%Net margin13.1%Free cash flow margin16.9%Fiscal year 2025Operating margin16.3%Net margin13.6%Free cash flow margin18.3%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin n/a −1,056.1% −37.7% −14.3% −13.5% 0.5% 10.4% 13.9% 13.4% 16.3%
Net margin n/a −1,054.6% −45.3% −27.8% −26.7% −11.5% 0.0% 9.2% 13.1% 13.6%
Free cash flow margin n/a −624.5% −9.8% 8.1% 0.3% 8.2% −6.9% 11.4% 16.9% 18.3%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−141.7Capital expenditure−4.3Free cash flow−146.0Fiscal year 2017Operating cash flow−172.5Capital expenditure−0.4Free cash flow−172.9Fiscal year 2018Operating cash flow−24.1Capital expenditure−0.4Free cash flow−24.5Fiscal year 2019Operating cash flow22.4Capital expenditure−0.3Free cash flow22.1Fiscal year 2020Operating cash flow0.8Capital expenditure−0.0Free cash flow0.7 −96.7%Fiscal year 2021Operating cash flow20.7Capital expenditure0.0Free cash flow20.7 +2,740.4%Fiscal year 2022Operating cash flow−15.8Capital expenditure0.0Free cash flow−15.8 −176.6%Fiscal year 2023Operating cash flow27.0Capital expenditure−0.1Free cash flow26.9Fiscal year 2024Operating cash flow38.9Capital expenditure−0.1Free cash flow38.9 +44.6%Fiscal year 2025Operating cash flow41.8Capital expenditure−0.1Free cash flow41.7 +7.4%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −141.7 −172.5 −24.1 22.4 0.8 20.7 −15.8 27.0 38.9 41.8
Capital expenditure −4.3 −0.4 −0.4 −0.3 −0.0 0.0 0.0 −0.1 −0.1 −0.1
Free cash flow −146.0 −172.9 −24.5 22.1 0.7 20.7 −15.8 26.9 38.9 41.7
Growth −96.7% +2,740.4% −176.6% +44.6% +7.4%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash194.5Shareholders’ equity209.8Fiscal year 2017Cash81.7Total debt48.5Net cash (debt)33.2Shareholders’ equity53.3Debt to equity0.91Fiscal year 2018Cash108.4Total debt151.9Net cash (debt)−43.5Shareholders’ equity34.3Debt to equity4.43Fiscal year 2019Cash60.0Total debt95.0Net cash (debt)−34.9Shareholders’ equity17.5Debt to equity5.44Fiscal year 2020Cash85.3Total debt98.3Net cash (debt)−13.0Shareholders’ equity−6.0Fiscal year 2021Cash63.1Total debt97.1Net cash (debt)−34.0Shareholders’ equity−2.4Fiscal year 2022Cash76.2Total debt98.3Net cash (debt)−22.1Shareholders’ equity21.6Debt to equity4.55Fiscal year 2023Cash84.6Total debt99.7Net cash (debt)−15.1Shareholders’ equity53.4Debt to equity1.86Fiscal year 2024Cash69.2Total debt67.0Net cash (debt)2.2Shareholders’ equity92.1Debt to equity0.73Fiscal year 2025Cash29.6Total debt22.5Net cash (debt)7.1Shareholders’ equity130.3Debt to equity0.17
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 194.5 81.7 108.4 60.0 85.3 63.1 76.2 84.6 69.2 29.6
Total debt n/a 48.5 151.9 95.0 98.3 97.1 98.3 99.7 67.0 22.5
Net cash (debt) n/a 33.2 −43.5 −34.9 −13.0 −34.0 −22.1 −15.1 2.2 7.1
Shareholders’ equity 209.8 53.3 34.3 17.5 −6.0 −2.4 21.6 53.4 92.1 130.3
Debt to equity n/a 0.91 4.43 5.44 n/a n/a 4.55 1.86 0.73 0.17

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Cash flow

In millions of USD, except per-share figures; shares in millions. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Operations
−141.7 −172.5 −24.1 22.4 0.8 20.7 −15.8 27.0 38.9 41.8
Growth −96.5% +2,571.4% −176.6% +44.1% +7.4%
Investment
−4.3 −0.4 −0.4 −0.3 −0.0 0.0 0.0 −0.1 −0.1 −0.1
calc −146.0 −172.9 −24.5 22.1 0.7 20.7 −15.8 26.9 38.9 41.7
Growth −96.7% +2,740.4% −176.6% +44.6% +7.4%
calc n/a n/a n/a n/a 0.02 0.51 −0.35 0.57 0.79 0.82
142.2 −15.4 −57.6 5.2 33.4 −10.9 7.1 −19.1 −20.4 −36.2
Financing
162.4 75.1 108.5 −67.1 −9.9 −31.9 12.2 0.0 −33.8 −45.2

Lines marked calc are worked out here from filed figures; point at one for how. Capital expenditure, dividends and buybacks are shown as money out, so negative.