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Stocks · Health care · Pharmaceutical Preparations

ProQR Therapeutics N.V.

PRQR Clue Score64
Netherlands Fiscal year ends December CIK 0001612940
$1.63 +3.82% Close, 9 Oct 2026
Alert on the numbers Alert on insider trades
Price $1.63 −78.80% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Operating income−39.6Net income−39.1Fiscal year 2017Operating income−40.5Net income−43.6Fiscal year 2018Operating income−36.3Net income−36.9Fiscal year 2019Operating income−57.4Net income−56.5EPS, diluted−1.38Fiscal year 2020Operating income−42.4Net income−46.6EPS, diluted−0.93Fiscal year 2021Revenue1.4Operating income−57.2Net income−60.7EPS, diluted−0.95Fiscal year 2022Revenue3.6 +165.4%Operating income−65.2Net income−64.4EPS, diluted−0.90Fiscal year 2023Revenue6.5 +81.2%Operating income−31.9Net income−28.1EPS, diluted−0.35Fiscal year 2024Revenue18.9 +190.2%Operating income−30.5Net income−27.8EPS, diluted−0.32Fiscal year 2025Revenue15.9 −15.9%Operating income−43.4Net income−42.2EPS, diluted−0.40
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue n/a n/a n/a n/a n/a 1.4 3.6 6.5 18.9 15.9
Growth +165.4% +81.2% +190.2% −15.9%
Operating income −39.6 −40.5 −36.3 −57.4 −42.4 −57.2 −65.2 −31.9 −30.5 −43.4
Net income −39.1 −43.6 −36.9 −56.5 −46.6 −60.7 −64.4 −28.1 −27.8 −42.2
Growth
EPS, diluted n/a n/a n/a −1.38 −0.93 −0.95 −0.90 −0.35 −0.32 −0.40
Growth

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Fiscal year 2017Fiscal year 2018Fiscal year 2019Fiscal year 2020Fiscal year 2021Operating margin−4,225.3%Net margin−4,486.0%Free cash flow margin−1,956.9%Fiscal year 2022Operating margin−1,813.0%Net margin−1,792.5%Free cash flow margin−1,925.9%Fiscal year 2023Operating margin−489.1%Net margin−431.7%Free cash flow margin309.7%Fiscal year 2024Operating margin−161.2%Net margin−146.9%Free cash flow margin−200.0%Fiscal year 2025Operating margin−273.1%Net margin−265.2%Free cash flow margin−338.3%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin n/a n/a n/a n/a n/a −4,225.3% −1,813.0% −489.1% −161.2% −273.1%
Net margin n/a n/a n/a n/a n/a −4,486.0% −1,792.5% −431.7% −146.9% −265.2%
Free cash flow margin n/a n/a n/a n/a n/a −1,956.9% −1,925.9% 309.7% −200.0% −338.3%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−34.2Capital expenditure−2.5Free cash flow−36.8Fiscal year 2017Operating cash flow−35.0Capital expenditure−0.1Free cash flow−35.1Fiscal year 2018Operating cash flow−28.5Capital expenditure−0.3Free cash flow−28.8Fiscal year 2019Operating cash flow−44.0Capital expenditure−0.6Free cash flow−44.6Fiscal year 2020Operating cash flow−47.1Capital expenditure−0.9Free cash flow−48.0Fiscal year 2021Operating cash flow−26.0Capital expenditure−0.5Free cash flow−26.5Fiscal year 2022Operating cash flow−68.5Capital expenditure−0.7Free cash flow−69.2Fiscal year 2023Operating cash flow21.5Capital expenditure−1.4Free cash flow20.2Fiscal year 2024Operating cash flow−36.4Capital expenditure−1.4Free cash flow−37.8 −287.4%Fiscal year 2025Operating cash flow−52.8Capital expenditure−1.0Free cash flow−53.8
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −34.2 −35.0 −28.5 −44.0 −47.1 −26.0 −68.5 21.5 −36.4 −52.8
Capital expenditure −2.5 −0.1 −0.3 −0.6 −0.9 −0.5 −0.7 −1.4 −1.4 −1.0
Free cash flow −36.8 −35.1 −28.8 −44.6 −48.0 −26.5 −69.2 20.2 −37.8 −53.8
Growth −287.4%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash59.2Total debt5.7Net cash (debt)53.5Shareholders’ equity53.1Debt to equity0.11Fiscal year 2017Cash48.1Total debt5.3Net cash (debt)42.8Shareholders’ equity39.4Debt to equity0.13Fiscal year 2018Cash105.6Total debt9.4Net cash (debt)96.2Shareholders’ equity92.9Debt to equity0.10Fiscal year 2019Cash112.0Total debt12.7Net cash (debt)99.2Shareholders’ equity94.3Debt to equity0.13Fiscal year 2020Cash75.8Total debt17.3Net cash (debt)58.5Shareholders’ equity57.1Debt to equity0.30Fiscal year 2021Cash187.5Total debt44.1Net cash (debt)143.4Shareholders’ equity113.8Debt to equity0.39Fiscal year 2022Cash94.8Total debt6.8Net cash (debt)88.0Shareholders’ equity67.1Debt to equity0.10Fiscal year 2023Cash118.9Total debt4.3Net cash (debt)114.6Shareholders’ equity41.4Debt to equity0.10Fiscal year 2024Cash149.4Shareholders’ equity88.6Fiscal year 2025Cash92.4Shareholders’ equity49.4
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 59.2 48.1 105.6 112.0 75.8 187.5 94.8 118.9 149.4 92.4
Total debt 5.7 5.3 9.4 12.7 17.3 44.1 6.8 4.3 n/a n/a
Net cash (debt) 53.5 42.8 96.2 99.2 58.5 143.4 88.0 114.6 n/a n/a
Shareholders’ equity 53.1 39.4 92.9 94.3 57.1 113.8 67.1 41.4 88.6 49.4
Debt to equity 0.11 0.13 0.10 0.13 0.30 0.39 0.10 0.10 n/a n/a

In millions of EUR, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
n/a n/a n/a n/a n/a −4,225.3% −1,813.0% −489.1% −161.2% −273.1%
n/a n/a n/a n/a n/a −4,481.7% −1,783.8% −427.0% −147.9% −265.1%
n/a n/a n/a n/a n/a −4,486.0% −1,792.5% −431.7% −146.9% −265.2%
n/a n/a n/a n/a n/a −1,956.9% −1,925.9% 309.7% −200.0% −338.3%
Spending
n/a n/a n/a n/a n/a 3,118.2% 1,415.3% 386.1% 192.3% 281.2%
n/a n/a n/a n/a n/a 1,282.7% 518.9% 249.2% 72.3% 94.7%
n/a n/a n/a n/a n/a 35.7% 19.7% 21.0% 7.5% 6.4%
Returns
−73.6% −110.9% −39.7% −59.9% −81.6% −53.4% −96.1% −67.9% −31.3% −85.4%
−59.7% −82.2% −33.5% −48.1% −47.2% −29.0% −37.6% −20.4% −16.5% −37.4%
Balance and payout
0.11 0.13 0.10 0.13 0.30 0.39 0.10 0.10 n/a n/a
18.9% 25.9% 15.9% 20.2% 42.7% 46.0% 61.1% 70.0% 47.3% 56.2%

Shown in EUR as filed; the screener converts to dollars.