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Stocks · Health care · Pharmaceutical Preparations

uniQure N.V.

QURE Clue Score22
Fiscal year ends December CIK 0001590560
$22.59 +0.22% Close, 9 Oct 2026
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Price $22.59 −25.67% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue25.1Operating income−71.9Net income−73.4Fiscal year 2017Revenue13.1 −47.8%Operating income−71.3Net income−79.3Fiscal year 2018Revenue11.3 −13.9%Operating income−88.2Net income−83.3Fiscal year 2019Revenue7.3 −35.5%Operating income−121.1Net income−124.2EPS, diluted−3.11Fiscal year 2020Revenue37.5 +415.2%Operating income−125.4Net income−125.0EPS, diluted−2.81Fiscal year 2021Revenue524.0 +1,296.8%Operating income310.6EPS, diluted7.04Fiscal year 2022Revenue106.5 −79.7%Operating income−143.2EPS, diluted−2.71 −138.5%Fiscal year 2023Revenue15.8 −85.1%Operating income−282.9Net income−308.5EPS, diluted−6.47Fiscal year 2024Revenue27.1 +71.2%Operating income−184.3Net income−239.6EPS, diluted−4.92Fiscal year 2025Revenue16.1 −40.6%Operating income−185.3Net income−199.0EPS, diluted−3.46
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 25.1 13.1 11.3 7.3 37.5 524.0 106.5 15.8 27.1 16.1
Growth −47.8% −13.9% −35.5% +415.2% +1,296.8% −79.7% −85.1% +71.2% −40.6%
Operating income −71.9 −71.3 −88.2 −121.1 −125.4 310.6 −143.2 −282.9 −184.3 −185.3
Net income −73.4 −79.3 −83.3 −124.2 −125.0 n/a n/a −308.5 −239.6 −199.0
Growth
EPS, diluted n/a n/a n/a −3.11 −2.81 7.04 −2.71 −6.47 −4.92 −3.46
Growth −138.5%

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Operating margin−286.7%Net margin−292.3%Free cash flow margin−348.5%Fiscal year 2017Operating margin−544.3%Net margin−604.7%Free cash flow margin−524.4%Fiscal year 2018Operating margin−781.9%Net margin−738.2%Free cash flow margin−695.0%Fiscal year 2019Operating margin−1,663.8%Net margin−1,705.8%Free cash flow margin−1,433.0%Fiscal year 2020Operating margin−334.3%Net margin−333.3%Free cash flow margin−378.8%Fiscal year 2021Operating margin59.3%Free cash flow margin51.6%Fiscal year 2022Operating margin−134.4%Free cash flow margin−152.8%Fiscal year 2023Operating margin−1,785.5%Net margin−1,947.1%Free cash flow margin−966.3%Fiscal year 2024Operating margin−679.6%Net margin−883.4%Free cash flow margin−686.2%Fiscal year 2025Operating margin−1,151.4%Net margin−1,236.0%Free cash flow margin−1,108.2%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin −286.7% −544.3% −781.9% −1,663.8% −334.3% 59.3% −134.4% −1,785.5% −679.6% −1,151.4%
Net margin −292.3% −604.7% −738.2% −1,705.8% −333.3% n/a n/a −1,947.1% −883.4% −1,236.0%
Free cash flow margin −348.5% −524.4% −695.0% −1,433.0% −378.8% 51.6% −152.8% −966.3% −686.2% −1,108.2%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−72.2Capital expenditure−15.3Free cash flow−87.5Fiscal year 2017Operating cash flow−64.3Capital expenditure−4.5Free cash flow−68.7Fiscal year 2018Operating cash flow−76.0Capital expenditure−2.4Free cash flow−78.4Fiscal year 2019Operating cash flow−98.7Capital expenditure−5.7Free cash flow−104.3Fiscal year 2020Operating cash flow−134.8Capital expenditure−7.3Free cash flow−142.1Fiscal year 2021Operating cash flow288.0Capital expenditure−17.4Free cash flow270.5Fiscal year 2022Operating cash flow−145.1Capital expenditure−17.7Free cash flow−162.7 −160.2%Fiscal year 2023Operating cash flow−145.9Capital expenditure−7.2Free cash flow−153.1Fiscal year 2024Operating cash flow−182.7Capital expenditure−3.4Free cash flow−186.1Fiscal year 2025Operating cash flow−178.0Capital expenditure−0.4Free cash flow−178.4
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −72.2 −64.3 −76.0 −98.7 −134.8 288.0 −145.1 −145.9 −182.7 −178.0
Capital expenditure −15.3 −4.5 −2.4 −5.7 −7.3 −17.4 −17.7 −7.2 −3.4 −0.4
Free cash flow −87.5 −68.7 −78.4 −104.3 −142.1 270.5 −162.7 −153.1 −186.1 −178.4
Growth −160.2%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash132.5Total debt20.2Net cash (debt)112.3Shareholders’ equity63.6Debt to equity0.32Fiscal year 2017Cash159.4Total debt20.8Net cash (debt)138.6Shareholders’ equity89.4Debt to equity0.23Fiscal year 2018Cash234.9Total debt35.5Net cash (debt)199.4Shareholders’ equity179.6Debt to equity0.20Fiscal year 2019Cash377.8Total debt36.1Net cash (debt)341.7Shareholders’ equity323.1Debt to equity0.11Fiscal year 2020Cash244.9Total debt35.6Net cash (debt)209.3Shareholders’ equity243.9Debt to equity0.15Fiscal year 2021Cash556.3Total debt101.0Net cash (debt)455.3Shareholders’ equity595.8Debt to equity0.17Fiscal year 2022Cash228.0Total debt102.8Net cash (debt)125.2Shareholders’ equity476.0Debt to equity0.22Fiscal year 2023Cash241.4Total debt101.7Net cash (debt)139.6Shareholders’ equity207.7Debt to equity0.49Fiscal year 2024Cash158.9Total debt51.3Net cash (debt)107.6Shareholders’ equity−6.8Fiscal year 2025Cash80.2Total debt49.7Net cash (debt)30.5Shareholders’ equity198.9Debt to equity0.25
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 132.5 159.4 234.9 377.8 244.9 556.3 228.0 241.4 158.9 80.2
Total debt 20.2 20.8 35.5 36.1 35.6 101.0 102.8 101.7 51.3 49.7
Net cash (debt) 112.3 138.6 199.4 341.7 209.3 455.3 125.2 139.6 107.6 30.5
Shareholders’ equity 63.6 89.4 179.6 323.1 243.9 595.8 476.0 207.7 −6.8 198.9
Debt to equity 0.32 0.23 0.20 0.11 0.15 0.17 0.22 0.49 n/a 0.25

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
−286.7% −544.3% −781.9% −1,663.8% −334.3% 59.3% −134.4% −1,785.5% −679.6% −1,151.4%
−287.8% −606.2% −736.2% −1,705.8% −377.0% 63.5% −120.5% −1,935.0% −874.4% −1,201.0%
−292.3% −604.7% −738.2% −1,705.8% −333.3% n/a n/a −1,947.1% −883.4% −1,236.0%
−348.5% −524.4% −695.0% −1,433.0% −378.8% 51.6% −152.8% −966.3% −686.2% −1,108.2%
Spending
288.9% 550.6% 663.0% 1,301.2% 326.3% 27.4% 185.6% 1,356.2% 530.2% 873.9%
103.6% 188.0% 224.3% 460.7% 113.5% 10.7% 51.7% 470.8% 194.2% 406.6%
60.9% 34.0% 21.1% 77.6% 19.4% 3.3% 16.6% 45.2% 12.4% 2.7%
n/a n/a n/a n/a n/a 1.0% n/a n/a n/a n/a
Returns
−115.3% −88.7% −46.4% −38.4% −51.3% n/a n/a −148.5% n/a −100.0%
−38.6% −37.8% −30.4% −27.7% −36.7% n/a n/a −37.1% −43.0% −24.1%
Balance and payout
0.32 0.23 0.20 0.11 0.15 0.17 0.22 0.49 n/a 0.25
66.6% 57.4% 34.4% 28.0% 28.3% 26.4% 32.5% 75.0% 101.2% 75.9%