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Silence Therapeutics plc

SLN Clue Score22
United Kingdom CIK 0001479615
$9.86 +3.57% Close, 9 Oct 2026
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Price $9.86 −53.52% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 8 Sep 2020. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2018Operating income−20.6Net income−18.4Fiscal year 2019Revenue0.2Operating income−22.7Net income−19.6Fiscal year 2020Revenue5.3 +2,072.1%Operating income−35.8Net income−32.5Fiscal year 2021Revenue12.4 +134.2%Operating income−45.8Net income−39.4Fiscal year 2022Revenue21.7 +74.4%Operating income−61.0Net income−50.3EPS, diluted−0.52Fiscal year 2023Revenue31.6 +46.1%Operating income−64.4Net income−54.2EPS, diluted−0.49Fiscal year 2024Revenue43.3 +36.7%Operating income−63.3Net income−45.3EPS, diluted−0.33Fiscal year 2025Revenue0.6 −98.7%Operating income−91.1Net income−88.6EPS, diluted−0.63
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue n/a 0.2 5.3 12.4 21.7 31.6 43.3 0.6
Growth +2,072.1% +134.2% +74.4% +46.1% +36.7% −98.7%
Operating income −20.6 −22.7 −35.8 −45.8 −61.0 −64.4 −63.3 −91.1
Net income −18.4 −19.6 −32.5 −39.4 −50.3 −54.2 −45.3 −88.6
Growth
EPS, diluted n/a n/a n/a n/a −0.52 −0.49 −0.33 −0.63
Growth

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Gross marginOperating marginNet margin
Fiscal year 2018Fiscal year 2019Gross margin100.0%Operating margin−9,317.2%Net margin−8,025.4%Free cash flow margin704.1%Fiscal year 2020Gross margin32.4%Operating margin−676.4%Net margin−614.1%Free cash flow margin−213.0%Fiscal year 2021Gross margin39.9%Operating margin−369.0%Net margin−317.4%Free cash flow margin44.3%Fiscal year 2022Gross margin30.6%Operating margin−281.9%Net margin−232.4%Free cash flow margin−264.2%Fiscal year 2023Gross margin47.6%Operating margin−203.5%Net margin−171.4%Free cash flow margin−156.5%Fiscal year 2024Operating margin−146.4%Net margin−104.7%Free cash flow margin−156.9%Fiscal year 2025Operating margin−16,292.8%Net margin−15,851.9%Free cash flow margin−11,149.6%
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Gross margin n/a 100.0% 32.4% 39.9% 30.6% 47.6% n/a n/a
Operating margin n/a −9,317.2% −676.4% −369.0% −281.9% −203.5% −146.4% −16,292.8%
Net margin n/a −8,025.4% −614.1% −317.4% −232.4% −171.4% −104.7% −15,851.9%
Free cash flow margin n/a 704.1% −213.0% 44.3% −264.2% −156.5% −156.9% −11,149.6%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2018Operating cash flow−16.8Capital expenditure−0.1Free cash flow−16.9Fiscal year 2019Operating cash flow1.7Capital expenditure−0.0Free cash flow1.7Fiscal year 2020Operating cash flow−10.8Capital expenditure−0.5Free cash flow−11.3 −757.0%Fiscal year 2021Operating cash flow6.8Capital expenditure−1.3Free cash flow5.5Fiscal year 2022Operating cash flow−57.0Capital expenditure−0.2Free cash flow−57.2 −1,141.3%Fiscal year 2023Operating cash flow−49.5Capital expenditure−0.1Free cash flow−49.5Fiscal year 2024Operating cash flow−67.6Capital expenditure−0.2Free cash flow−67.9Fiscal year 2025Operating cash flow−62.3Capital expenditure−0.1Free cash flow−62.3
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −16.8 1.7 −10.8 6.8 −57.0 −49.5 −67.6 −62.3
Capital expenditure −0.1 −0.0 −0.5 −1.3 −0.2 −0.1 −0.2 −0.1
Free cash flow −16.9 1.7 −11.3 5.5 −57.2 −49.5 −67.9 −62.3
Growth −757.0% −1,141.3%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2018Cash21.5Shareholders’ equity35.1Fiscal year 2019Cash13.5Shareholders’ equity20.9Fiscal year 2020Cash27.4Shareholders’ equity9.1Fiscal year 2021Cash73.5Shareholders’ equity12.4Fiscal year 2022Cash54.8Shareholders’ equity27.2Fiscal year 2023Cash68.8Shareholders’ equity22.0Fiscal year 2024Cash121.3Shareholders’ equity134.0Fiscal year 2025Cash11.3Shareholders’ equity62.3
FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 21.5 13.5 27.4 73.5 54.8 68.8 121.3 11.3
Shareholders’ equity 35.1 20.9 9.1 12.4 27.2 22.0 134.0 62.3

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
n/a 100.0% 32.4% 39.9% 30.6% 47.6% n/a n/a
n/a −9,317.2% −676.4% −369.0% −281.9% −203.5% −146.4% −16,292.8%
n/a −9,373.0% −680.0% −369.4% −229.3% −168.4% −102.8% −15,849.9%
n/a −8,025.4% −614.1% −317.4% −232.4% −171.4% −104.7% −15,851.9%
n/a 704.1% −213.0% 44.3% −264.2% −156.5% −156.9% −11,149.6%
Spending
n/a 5,465.6% 381.3% 247.8% 164.4% 139.1% n/a n/a
n/a 3,951.6% 263.8% 161.2% 90.6% 65.2% n/a n/a
n/a 3.7% 9.6% 10.6% 0.8% 0.2% 0.5% 9.8%
Returns
−52.5% −93.7% −359.3% −318.5% −184.9% −246.6% −33.8% −142.2%
n/a n/a n/a n/a n/a −45.4% −22.4% −67.4%
Balance and payout
n/a n/a n/a n/a n/a 81.6% 33.9% 52.6%