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Stocks · Health care · Pharmaceutical Preparations

Syndax Pharmaceuticals Inc

SNDX Clue Score33
United States Fiscal year ends December CIK 0001395937
$16.99 +0.53% Close, 9 Oct 2026
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Price $16.99 −4.12% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue1.2Operating income−43.8Net income−44.5Fiscal year 2017Revenue2.1 +72.8%Operating income−62.0Net income−60.8Fiscal year 2018Revenue1.5 −28.0%Operating income−75.9Net income−74.0Fiscal year 2019Revenue1.5 +0.0%Operating income−57.5Net income−56.0EPS, diluted−1.84Fiscal year 2020Revenue1.5 +0.0%Operating income−71.4Net income−73.2EPS, diluted−1.87Fiscal year 2021Revenue139.7 +9,109.6%Operating income26.2Net income24.9EPS, diluted0.46Fiscal year 2022Revenue0.0 −100.0%Operating income−151.8Net income−149.3 −699.1%EPS, diluted−2.46 −634.8%Fiscal year 2023Revenue0.0Operating income−230.0Net income−209.4EPS, diluted−2.98Fiscal year 2024Revenue23.7Operating income−339.7Net income−318.8EPS, diluted−3.72Fiscal year 2025Revenue172.4 +627.8%Operating income−273.1Net income−285.4EPS, diluted−3.29
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 1.2 2.1 1.5 1.5 1.5 139.7 0.0 0.0 23.7 172.4
Growth +72.8% −28.0% +0.0% +0.0% +9,109.6% −100.0% +627.8%
Operating income −43.8 −62.0 −75.9 −57.5 −71.4 26.2 −151.8 −230.0 −339.7 −273.1
Net income −44.5 −60.8 −74.0 −56.0 −73.2 24.9 −149.3 −209.4 −318.8 −285.4
Growth −699.1%
EPS, diluted n/a n/a n/a −1.84 −1.87 0.46 −2.46 −2.98 −3.72 −3.29
Growth −634.8%

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Operating margin−3,587.4%Net margin−3,645.2%Free cash flow margin−2,903.1%Fiscal year 2017Operating margin−2,939.0%Net margin−2,884.3%Free cash flow margin−2,251.2%Fiscal year 2018Operating margin−5,001.7%Net margin−4,875.5%Free cash flow margin−4,529.9%Fiscal year 2019Operating margin−3,792.9%Net margin−3,694.6%Fiscal year 2020Operating margin−4,708.2%Net margin−4,822.5%Free cash flow margin−4,697.4%Fiscal year 2021Operating margin18.8%Net margin17.8%Free cash flow margin20.8%Fiscal year 2022Fiscal year 2023Fiscal year 2024Operating margin−1,434.4%Net margin−1,346.1%Free cash flow margin−1,160.9%Fiscal year 2025Operating margin−158.4%Net margin−165.6%Free cash flow margin−187.5%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin −3,587.4% −2,939.0% −5,001.7% −3,792.9% −4,708.2% 18.8% n/a n/a −1,434.4% −158.4%
Net margin −3,645.2% −2,884.3% −4,875.5% −3,694.6% −4,822.5% 17.8% n/a n/a −1,346.1% −165.6%
Free cash flow margin −2,903.1% −2,251.2% −4,529.9% n/a −4,697.4% 20.8% n/a n/a −1,160.9% −187.5%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−35.2Capital expenditure−0.3Free cash flow−35.4Fiscal year 2017Operating cash flow−47.4Capital expenditure−0.1Free cash flow−47.5Fiscal year 2018Operating cash flow−68.5Capital expenditure−0.2Free cash flow−68.7Fiscal year 2019Operating cash flow−50.6Fiscal year 2020Operating cash flow−71.3Capital expenditure0.0Free cash flow−71.3Fiscal year 2021Operating cash flow29.1Capital expenditure−0.1Free cash flow29.0Fiscal year 2022Operating cash flow−133.7Capital expenditure0.0Free cash flow−133.7 −560.9%Fiscal year 2023Operating cash flow−160.6Capital expenditure0.0Free cash flow−160.6Fiscal year 2024Operating cash flow−274.9Capital expenditure0.0Free cash flow−274.9Fiscal year 2025Operating cash flow−323.0Capital expenditure−0.2Free cash flow−323.2
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −35.2 −47.4 −68.5 −50.6 −71.3 29.1 −133.7 −160.6 −274.9 −323.0
Capital expenditure −0.3 −0.1 −0.2 n/a 0.0 −0.1 0.0 0.0 0.0 −0.2
Free cash flow −35.4 −47.5 −68.7 n/a −71.3 29.0 −133.7 −160.6 −274.9 −323.2
Growth −560.9%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
CashTotal debt
Fiscal year 2016Cash23.8Shareholders’ equity84.1Fiscal year 2017Cash35.2Shareholders’ equity104.3Fiscal year 2018Cash33.8Shareholders’ equity53.0Fiscal year 2019Cash24.6Shareholders’ equity31.6Fiscal year 2020Cash115.2Shareholders’ equity252.2Fiscal year 2021Cash222.0Shareholders’ equity408.4Fiscal year 2022Cash74.4Shareholders’ equity467.4Fiscal year 2023Cash295.4Total debt0.0Net cash (debt)295.4Shareholders’ equity554.2Debt to equity0.00Fiscal year 2024Cash154.1Total debt337.9Net cash (debt)−183.8Shareholders’ equity288.1Debt to equity1.17Fiscal year 2025Cash134.9Total debt350.0Net cash (debt)−215.1Shareholders’ equity64.6Debt to equity5.42
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 23.8 35.2 33.8 24.6 115.2 222.0 74.4 295.4 154.1 134.9
Total debt n/a n/a n/a n/a n/a n/a n/a 0.0 337.9 350.0
Net cash (debt) n/a n/a n/a n/a n/a n/a n/a 295.4 −183.8 −215.1
Shareholders’ equity 84.1 104.3 53.0 31.6 252.2 408.4 467.4 554.2 288.1 64.6
Debt to equity n/a n/a n/a n/a n/a n/a n/a 0.00 1.17 5.42

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Income statement

In millions of USD, except per-share figures; shares in millions. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Revenue and profit
1.2 2.1 1.5 1.5 1.5 139.7 0.0 0.0 23.7 172.4
Growth +72.8% −28.0% +0.0% +0.0% +9,109.6% −100.0% +627.8%
31.7 48.2 60.1 43.0 50.4 88.2 118.5 163.0 241.6 258.8
13.3 15.9 17.3 16.1 22.5 25.2 33.3 66.9 120.9 179.7
−43.8 −62.0 −75.9 −57.5 −71.4 26.2 −151.8 −230.0 −339.7 −273.1
Growth −678.8%
0.0 0.0 0.0 0.0 0.0 0.0 n/a n/a n/a 0.4
−44.5 −60.8 −74.0 −56.0 −73.2 24.9 −149.3 −209.4 −318.8 −285.4
Growth −699.1%
Per share
n/a n/a n/a −1.84 −1.87 0.48 −2.46 −2.98 −3.72 −3.29
n/a n/a n/a −1.84 −1.87 0.46 −2.46 −2.98 −3.72 −3.29
Growth −634.8%
n/a n/a n/a 30.5 41.3 52.1 60.8 70.4 85.6 86.6
n/a n/a n/a 30.5 41.3 53.6 60.8 70.4 85.6 86.6
Growth +35.5% +29.8% +13.3% +15.8% +21.7% +1.2%

Five years in brief

Worked out from the figures above, not from a press release
  • Revenue grew 157.7% a year over five years.
  • The diluted share count rose 109.7% in five years, which is dilution.
  • Operating margin is up 4,549.7 points on five years ago, at -158.4%.
  • A net loss in 9 of 10 years on file.