InsiderClue
Stocks · Health care · Pharmaceutical Preparations

Spyre Therapeutics, Inc.

SYRE Clue Score15
United States Fiscal year ends December CIK 0001636282 Results filed 3 Nov 2026
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What the insiders did Scheduled selling only

Individual transactions

94
Insider
Date
Role
Action
Shares
Price
Amount
Scott L Burrows
1 Oct 2026
Chief Financial Officer
Sold after exercise
229
$93.57
$21.43K
Scott L Burrows
1 Oct 2026
Chief Financial Officer
Sold after exercise
3,071
$92.95
$285.45K
Scott L Burrows
1 Oct 2026
Chief Financial Officer
Sold after exercise
2,100
$91.92
$193.03K
Scott L Burrows
1 Oct 2026
Chief Financial Officer
Sold after exercise
1,500
$90.27
$135.41K
Scott L Burrows
1 Oct 2026
Chief Financial Officer
Sold after exercise
600
$89.07
$53.44K
Cameron Turtle
1 Oct 2026
Chief Executive Officer
Sold on a plan
100
$93.91
$9.39K
Cameron Turtle
1 Oct 2026
Chief Executive Officer
Sold on a plan
4,990
$93.37
$465.92K
Cameron Turtle
1 Oct 2026
Chief Executive Officer
Sold on a plan
3,989
$92.31
$368.22K
Cameron Turtle
1 Oct 2026
Chief Executive Officer
Sold on a plan
2,638
$91.49
$241.35K
Cameron Turtle
1 Oct 2026
Chief Executive Officer
Sold on a plan
2,683
$90.10
$241.74K
Cameron Turtle
1 Oct 2026
Chief Executive Officer
Sold on a plan
600
$89.14
$53.48K
Heidy King-Jones
1 Oct 2026
See Remarks
Sold after exercise
2,600
$93.46
$243.00K
Heidy King-Jones
1 Oct 2026
See Remarks
Sold after exercise
2,100
$92.70
$194.67K
Heidy King-Jones
1 Oct 2026
See Remarks
Sold after exercise
7,228
$91.35
$660.28K
Heidy King-Jones
1 Oct 2026
See Remarks
Sold after exercise
16,605
$90.35
$1.50M
Heidy King-Jones
1 Oct 2026
See Remarks
Sold after exercise
400
$89.24
$35.70K
Scott L Burrows
30 Sep 2026
Chief Financial Officer
Sold after exercise
17,500
$89.89
$1.57M
Scott L Burrows
2 Sep 2026
Chief Financial Officer
Sold on a plan
18,232
$89.35
$1.63M
Heidy King-Jones
2 Sep 2026
See Remarks
Sold after exercise
400
$90.00
$36.00K
Cameron Turtle
1 Sep 2026
Chief Executive Officer
Sold on a plan
400
$89.07
$35.63K
Cameron Turtle
1 Sep 2026
Chief Executive Officer
Sold on a plan
3,700
$88.06
$325.82K
Cameron Turtle
1 Sep 2026
Chief Executive Officer
Sold on a plan
8,400
$87.15
$732.06K
Cameron Turtle
1 Sep 2026
Chief Executive Officer
Sold on a plan
2,500
$86.36
$215.90K
Scott L Burrows
1 Sep 2026
Chief Financial Officer
Sold after exercise
200
$89.04
$17.81K
Scott L Burrows
1 Sep 2026
Chief Financial Officer
Sold after exercise
2,016
$88.03
$177.47K
Scott L Burrows
1 Sep 2026
Chief Financial Officer
Sold after exercise
4,384
$87.11
$381.89K
Scott L Burrows
1 Sep 2026
Chief Financial Officer
Sold after exercise
900
$86.25
$77.63K
Heidy King-Jones
1 Sep 2026
See Remarks
Sold after exercise
400
$89.38
$35.75K
Heidy King-Jones
1 Sep 2026
See Remarks
Sold after exercise
6,206
$88.17
$547.18K
Heidy King-Jones
1 Sep 2026
See Remarks
Sold after exercise
16,548
$87.20
$1.44M
Heidy King-Jones
1 Sep 2026
See Remarks
Sold after exercise
4,845
$86.40
$418.61K
Jeffrey W. Albers
7 Aug 2026
Director
Sold after exercise indirect
10,000
$104.68
$1.05M
Jeffrey W. Albers
7 Aug 2026
Director
Sold after exercise indirect
8,000
$104.38
$835.04K
Jeffrey W. Albers
7 Aug 2026
Director
Sold after exercise
5,000
$104.47
$522.35K
Cameron Turtle
3 Aug 2026
Chief Executive Officer
Sold on a plan
16
$97.46
$1.56K
Cameron Turtle
3 Aug 2026
Chief Executive Officer
Sold on a plan
1,392
$96.82
$134.77K
Cameron Turtle
3 Aug 2026
Chief Executive Officer
Sold on a plan
5,635
$95.93
$540.57K
Cameron Turtle
3 Aug 2026
Chief Executive Officer
Sold on a plan
7,157
$95.10
$680.63K
Cameron Turtle
3 Aug 2026
Chief Executive Officer
Sold on a plan
800
$93.97
$75.18K
Scott L Burrows
3 Aug 2026
Chief Financial Officer
Sold after exercise
100
$97.10
$9.71K
Scott L Burrows
3 Aug 2026
Chief Financial Officer
Sold after exercise
2,300
$96.30
$221.49K
Scott L Burrows
3 Aug 2026
Chief Financial Officer
Sold after exercise
5,100
$95.21
$485.57K
Cameron Turtle
1 Jul 2026
Chief Executive Officer
Sold on a plan
590
$88.91
$52.46K
Cameron Turtle
1 Jul 2026
Chief Executive Officer
Sold on a plan
4,234
$88.12
$373.10K
Cameron Turtle
1 Jul 2026
Chief Executive Officer
Sold on a plan
10,176
$87.44
$889.79K
Sheldon Sloan
1 Jul 2026
Chief Medical Officer
Sold after exercise
1,834
$88.34
$162.02K
Sheldon Sloan
1 Jul 2026
Chief Medical Officer
Sold after exercise
6,500
$87.52
$568.88K
Scott L Burrows
1 Jul 2026
Chief Financial Officer
Sold after exercise
1,725
$88.37
$152.44K
Scott L Burrows
1 Jul 2026
Chief Financial Officer
Sold after exercise
5,775
$87.55
$505.60K
Scott L Burrows
25 Jun 2026
Chief Financial Officer
Sold after exercise
10,000
$87.14
$871.40K
Scott L Burrows
25 Jun 2026
Chief Financial Officer
Sold after exercise
5,000
$87.12
$435.60K
Fairmount Funds Management LLC
23 Jun 2026
Director
Sold after exercise indirect
4,684,781
$85.31
$399.66M
Michael Thomas Henderson
22 Jun 2026
Director
Sold on a plan
20,000
$100.00
$2.00M
Sheldon Sloan
3 Jun 2026
Chief Medical Officer
Sold after exercise
8,333
$75.00
$624.98K
Scott L Burrows
1 Jun 2026
Chief Financial Officer
Sold after exercise
3,100
$72.06
$223.39K
Scott L Burrows
1 Jun 2026
Chief Financial Officer
Sold after exercise
2,599
$70.77
$183.93K
Scott L Burrows
1 Jun 2026
Chief Financial Officer
Sold after exercise
1,801
$69.75
$125.62K
Cameron Turtle
1 Jun 2026
Chief Executive Officer
Sold on a plan
3,294
$71.38
$235.13K
Cameron Turtle
1 Jun 2026
Chief Executive Officer
Sold on a plan
8,149
$70.50
$574.50K
Cameron Turtle
1 Jun 2026
Chief Executive Officer
Sold on a plan
3,557
$69.40
$246.86K
Michael Thomas Henderson
8 May 2026
Director
Sold on a plan
19,269
$75.35
$1.45M
Michael Thomas Henderson
8 May 2026
Director
Sold on a plan
24,814
$74.76
$1.86M
Michael Thomas Henderson
8 May 2026
Director
Sold on a plan
33,513
$73.72
$2.47M
Michael Thomas Henderson
8 May 2026
Director
Sold on a plan
2,404
$72.57
$174.46K
Cameron Turtle
1 May 2026
Chief Executive Officer
Sold on a plan
300
$74.96
$22.49K
Cameron Turtle
1 May 2026
Chief Executive Officer
Sold on a plan
1,700
$74.23
$126.19K
Cameron Turtle
1 May 2026
Chief Executive Officer
Sold on a plan
3,100
$73.14
$226.73K
Cameron Turtle
1 May 2026
Chief Executive Officer
Sold on a plan
1,000
$71.76
$71.76K
Cameron Turtle
1 May 2026
Chief Executive Officer
Sold on a plan
3,600
$70.77
$254.77K
Cameron Turtle
1 May 2026
Chief Executive Officer
Sold on a plan
5,300
$69.54
$368.56K
Sheldon Sloan
1 May 2026
Chief Medical Officer
Sold after exercise
400
$75.37
$30.15K
Sheldon Sloan
1 May 2026
Chief Medical Officer
Sold after exercise
5,059
$74.60
$377.40K
Sheldon Sloan
1 May 2026
Chief Medical Officer
Sold after exercise
10,358
$73.74
$763.80K
Sheldon Sloan
1 May 2026
Chief Medical Officer
Sold after exercise
12,777
$72.94
$931.95K
Sheldon Sloan
1 May 2026
Chief Medical Officer
Sold after exercise
8,777
$71.56
$628.08K
Sheldon Sloan
1 May 2026
Chief Medical Officer
Sold after exercise
19,656
$70.61
$1.39M
Sheldon Sloan
1 May 2026
Chief Medical Officer
Sold after exercise
21,306
$69.53
$1.48M
Scott L Burrows
1 May 2026
Chief Financial Officer
Sold after exercise
12,500
$71.37
$892.13K
Scott L Burrows
1 Apr 2026
Chief Financial Officer
Sold after exercise
1,300
$49.98
$64.97K
Scott L Burrows
1 Apr 2026
Chief Financial Officer
Sold after exercise
6,200
$49.21
$305.10K
Sheldon Sloan
1 Apr 2026
Chief Medical Officer
Sold after exercise
7,958
$50.00
$397.90K
Cameron Turtle
1 Apr 2026
Chief Executive Officer
Sold on a plan
2,656
$49.92
$132.59K
Cameron Turtle
1 Apr 2026
Chief Executive Officer
Sold on a plan
12,344
$49.20
$607.32K
Scott L Burrows
3 Mar 2026
Chief Financial Officer
Sold after exercise
200
$41.66
$8.33K
Scott L Burrows
3 Mar 2026
Chief Financial Officer
Sold after exercise
2,300
$40.56
$93.29K
Cameron Turtle
2 Mar 2026
Chief Executive Officer
Sold on a plan
9,100
$42.49
$386.66K
Cameron Turtle
2 Mar 2026
Chief Executive Officer
Sold on a plan
5,900
$41.73
$246.21K
Cameron Turtle
2 Feb 2026
Chief Executive Officer
Sold on a plan
14,043
$32.87
$461.59K
Cameron Turtle
2 Feb 2026
Chief Executive Officer
Sold on a plan
957
$31.82
$30.45K
Cameron Turtle
2 Jan 2026
Chief Executive Officer
Sold on a plan
100
$32.39
$3.24K
Cameron Turtle
2 Jan 2026
Chief Executive Officer
Sold on a plan
2,191
$31.79
$69.65K
Cameron Turtle
2 Jan 2026
Chief Executive Officer
Sold on a plan
12,709
$30.47
$387.24K
Cameron Turtle
1 Dec 2025
Chief Executive Officer
Sold on a plan
4,005
$29.83
$119.47K
Cameron Turtle
1 Dec 2025
Chief Executive Officer
Sold on a plan
10,995
$28.73
$315.89K

What was left out

Form 4 filings counted 41
Amendments (4/A) skipped 0
Filings about a different issuer 0
Unreadable filings 0
Joint filings 2
Sales on a Rule 10b5-1 plan 44
Sales straight out of an exercise 50
Sales at will 0
Transactions with no price 0
Shares from compensation/vesting 987,697
History held since 12 Apr 2016