Insider
Date
Role
Action
Shares
Price
Amount
Dube Eric M
17 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
6,802
$64.95
$441.80K
Dube Eric M
17 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
101,691
$64.59
$6.57M
Heerma Peter
17 Sep 2026
EVP, CHIEF COMMERCIAL OFFICER
Sold after exercise
8,282
$65.07
$538.92K
ROTE WILLIAM E.
16 Sep 2026
Chief Research Officer
Sold after exercise
47,746
$63.61
$3.04M
ROTE WILLIAM E.
16 Sep 2026
Chief Research Officer
Sold after exercise
65,104
$63.12
$4.11M
Dube Eric M
16 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
96,125
$63.64
$6.12M
Dube Eric M
16 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
99,716
$63.26
$6.31M
Heerma Peter
16 Sep 2026
EVP, CHIEF COMMERCIAL OFFICER
Sold after exercise
79,113
$63.65
$5.04M
Heerma Peter
16 Sep 2026
EVP, CHIEF COMMERCIAL OFFICER
Sold after exercise
93,604
$63.25
$5.92M
ROTE WILLIAM E.
15 Sep 2026
Chief Research Officer
Sold after exercise
270
$65.31
$17.63K
ROTE WILLIAM E.
15 Sep 2026
Chief Research Officer
Sold after exercise
3,000
$63.65
$190.95K
ROTE WILLIAM E.
15 Sep 2026
Chief Research Officer
Sold after exercise
29,021
$62.66
$1.82M
ROTE WILLIAM E.
15 Sep 2026
Chief Research Officer
Sold after exercise
63,907
$61.99
$3.96M
Calvin Sandra
15 Sep 2026
SVP, CHIEF ACCOUNTING OFFICER
Sold after exercise
300
$63.66
$19.10K
Calvin Sandra
15 Sep 2026
SVP, CHIEF ACCOUNTING OFFICER
Sold after exercise
800
$62.85
$50.28K
Calvin Sandra
15 Sep 2026
SVP, CHIEF ACCOUNTING OFFICER
Sold after exercise
4,275
$62.14
$265.63K
Cline Christopher R.
15 Sep 2026
CHIEF FINANCIAL OFFICER
Sold after exercise
400
$65.31
$26.12K
Cline Christopher R.
15 Sep 2026
CHIEF FINANCIAL OFFICER
Sold after exercise
1,900
$63.69
$121.00K
Cline Christopher R.
15 Sep 2026
CHIEF FINANCIAL OFFICER
Sold after exercise
20,735
$62.61
$1.30M
Cline Christopher R.
15 Sep 2026
CHIEF FINANCIAL OFFICER
Sold after exercise
27,473
$62.00
$1.70M
Dube Eric M
15 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
270
$65.31
$17.63K
Dube Eric M
15 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
3,102
$63.64
$197.42K
Dube Eric M
15 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
28,796
$62.66
$1.80M
Dube Eric M
15 Sep 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
63,498
$61.99
$3.94M
REED ELIZABETH E
15 Sep 2026
Chief Legal Officer and GC
Sold after exercise
300
$65.31
$19.59K
REED ELIZABETH E
15 Sep 2026
Chief Legal Officer and GC
Sold after exercise
1,400
$63.69
$89.17K
REED ELIZABETH E
15 Sep 2026
Chief Legal Officer and GC
Sold after exercise
13,874
$62.63
$868.96K
REED ELIZABETH E
15 Sep 2026
Chief Legal Officer and GC
Sold after exercise
21,926
$62.03
$1.36M
Inrig Jula
15 Sep 2026
EVP, Head of R&D & CMO
Sold after exercise
400
$65.31
$26.12K
Inrig Jula
15 Sep 2026
EVP, Head of R&D & CMO
Sold after exercise
1,600
$63.69
$101.90K
Inrig Jula
15 Sep 2026
EVP, Head of R&D & CMO
Sold after exercise
17,284
$62.62
$1.08M
Inrig Jula
15 Sep 2026
EVP, Head of R&D & CMO
Sold after exercise
25,390
$62.02
$1.57M
Heerma Peter
15 Sep 2026
EVP, CHIEF COMMERCIAL OFFICER
Sold after exercise
1,431
$65.31
$93.46K
Heerma Peter
15 Sep 2026
EVP, CHIEF COMMERCIAL OFFICER
Sold after exercise
1,400
$63.65
$89.11K
Heerma Peter
15 Sep 2026
EVP, CHIEF COMMERCIAL OFFICER
Sold after exercise
27,421
$62.59
$1.72M
Heerma Peter
15 Sep 2026
EVP, CHIEF COMMERCIAL OFFICER
Sold after exercise
71,938
$62.05
$4.46M
Meckler Jeffrey A
10 Sep 2026
Director
Sold after exercise
3,100
$68.09
$211.07K
Meckler Jeffrey A
10 Sep 2026
Director
Sold after exercise
14,000
$67.46
$944.49K
Meckler Jeffrey A
10 Sep 2026
Director
Sold after exercise
1,200
$66.15
$79.38K
Meckler Jeffrey A
10 Sep 2026
Director
Sold after exercise
1,700
$65.39
$111.17K
Cline Christopher R.
2 Sep 2026
CHIEF FINANCIAL OFFICER
Sell
642
$66.37
$42.61K
LYONS GARY A
18 Aug 2026
Director
Sold after exercise
900
$63.86
$57.47K
LYONS GARY A
18 Aug 2026
Director
Sold after exercise
4,100
$63.27
$259.39K
LYONS GARY A
17 Aug 2026
Director
Sold after exercise
500
$64.16
$32.08K
LYONS GARY A
17 Aug 2026
Director
Sold after exercise
2,600
$63.50
$165.10K
LYONS GARY A
17 Aug 2026
Director
Sold after exercise
1,900
$62.53
$118.80K
Baynes Roy D.
12 Jun 2026
Director
Sold after exercise
4,500
$50.00
$225.00K
Coughlin Timothy
12 Jun 2026
Director
Sold after exercise
10,000
$50.07
$500.75K
Coughlin Timothy
15 May 2026
Director
Sold on a plan
3,250
$43.49
$141.34K
Cline Christopher R.
6 May 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
310
$43.95
$13.62K
Dube Eric M
6 May 2026
CHIEF EXECUTIVE OFFICER
Sold on a plan
22,500
$43.95
$988.88K
Inrig Jula
6 May 2026
CHIEF MEDICAL OFFICER
Sold on a plan
311
$43.95
$13.67K
REED ELIZABETH E
6 May 2026
Chief Legal Officer and GC
Sold on a plan
2,076
$43.95
$91.24K
ROTE WILLIAM E.
6 May 2026
Chief Research Officer
Sold on a plan
2,763
$43.95
$121.43K
Cline Christopher R.
5 May 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
2,181
$46.65
$101.74K
Heerma Peter
5 May 2026
CHIEF COMMERCIAL OFFICER
Sell
2,174
$46.65
$101.42K
Inrig Jula
5 May 2026
CHIEF MEDICAL OFFICER
Sold on a plan
2,174
$46.65
$101.42K
REED ELIZABETH E
5 May 2026
Chief Legal Officer and GC
Sold on a plan
2,174
$46.65
$101.42K
Baynes Roy D.
5 May 2026
Director
Sold after exercise
4,500
$46.65
$209.93K
Inrig Jula
4 May 2026
CHIEF MEDICAL OFFICER
Sold after exercise
20,000
$45.00
$900.00K
REED ELIZABETH E
4 May 2026
Chief Legal Officer and GC
Sold after exercise
20,000
$45.00
$900.00K
Meckler Jeffrey A
4 May 2026
Director
Sold after exercise
8,000
$45.00
$360.00K
Baynes Roy D.
1 May 2026
Director
Sold after exercise
9,750
$44.22
$431.15K
ROTE WILLIAM E.
22 Apr 2026
Chief Research Officer
Sold on a plan
9,100
$39.09
$355.72K
Inrig Jula
15 Apr 2026
CHIEF MEDICAL OFFICER
Sold on a plan
1,018
$42.61
$43.38K
Cline Christopher R.
15 Apr 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
1,014
$42.61
$43.21K
REED ELIZABETH E
15 Apr 2026
Chief Legal Officer and GC
Sold on a plan
1,559
$42.53
$66.30K
REED ELIZABETH E
15 Apr 2026
Chief Legal Officer and GC
Sold on a plan
5,226
$41.62
$217.51K
Dube Eric M
15 Apr 2026
CHIEF EXECUTIVE OFFICER
Sold on a plan
20
$42.66
$853.20
Dube Eric M
15 Apr 2026
CHIEF EXECUTIVE OFFICER
Sold on a plan
7,165
$41.75
$299.14K
Dube Eric M
15 Apr 2026
CHIEF EXECUTIVE OFFICER
Sold on a plan
56,815
$41.01
$2.33M
Inrig Jula
14 Apr 2026
CHIEF MEDICAL OFFICER
Sold on a plan
7,215
$41.93
$302.52K
Cline Christopher R.
14 Apr 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
7,239
$41.93
$303.52K
Cline Christopher R.
14 Apr 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
9
$41.07
$369.63
REED ELIZABETH E
14 Apr 2026
Chief Legal Officer and GC
Sold after exercise
7,215
$41.93
$302.52K
REED ELIZABETH E
14 Apr 2026
Chief Legal Officer and GC
Sold after exercise
37,500
$41.07
$1.54M
Heerma Peter
14 Apr 2026
CHIEF COMMERCIAL OFFICER
Sell
7,215
$41.93
$302.52K
Calvin Sandra
14 Apr 2026
SVP, CHIEF ACCOUNTING OFFICER
Sold after exercise
21,977
$41.07
$902.60K
Baynes Roy D.
14 Apr 2026
Director
Sold after exercise
6,750
$42.12
$284.31K
Baynes Roy D.
14 Apr 2026
Director
Sold after exercise
26,000
$41.07
$1.07M
LYONS GARY A
14 Apr 2026
Director
Sold after exercise
8,000
$41.07
$328.56K
Cline Christopher R.
13 Apr 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
65
$28.85
$1.88K
Baynes Roy D.
6 Apr 2026
Director
Sold after exercise
10,000
$33.00
$330.00K
REED ELIZABETH E
1 Apr 2026
Chief Legal Officer and GC
Sold after exercise
10,000
$30.00
$300.00K
Dube Eric M
1 Apr 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
25,098
$31.46
$789.58K
Dube Eric M
1 Apr 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
34,902
$30.55
$1.07M
REED ELIZABETH E
16 Mar 2026
Chief Legal Officer and GC
Sold after exercise
10,000
$28.09
$280.86K
Dube Eric M
20 Feb 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
60,000
$30.10
$1.81M
REED ELIZABETH E
17 Feb 2026
Chief Legal Officer and GC
Sold after exercise
4,321
$28.26
$122.12K
REED ELIZABETH E
17 Feb 2026
Chief Legal Officer and GC
Sold after exercise
5,679
$27.50
$156.20K
REED ELIZABETH E
4 Feb 2026
Chief Legal Officer and GC
Sold on a plan
509
$32.74
$16.66K
REED ELIZABETH E
4 Feb 2026
Chief Legal Officer and GC
Sold on a plan
2,485
$32.07
$79.69K
Cline Christopher R.
4 Feb 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
110
$32.90
$3.62K
Cline Christopher R.
4 Feb 2026
CHIEF FINANCIAL OFFICER
Sold on a plan
1,635
$32.14
$52.55K
Inrig Jula
4 Feb 2026
CHIEF MEDICAL OFFICER
Sold on a plan
232
$32.85
$7.62K
Inrig Jula
4 Feb 2026
CHIEF MEDICAL OFFICER
Sold on a plan
1,547
$32.11
$49.67K
REED ELIZABETH E
3 Feb 2026
Chief Legal Officer and GC
Sell
7,175
$32.12
$230.46K
Calvin Sandra
3 Feb 2026
SVP, CHIEF ACCOUNTING OFFICER
Sell
4,333
$32.12
$139.18K
ROTE WILLIAM E.
3 Feb 2026
Chief Research Officer
Sold on a plan
12,446
$32.87
$409.10K
Heerma Peter
3 Feb 2026
CHIEF COMMERCIAL OFFICER
Sell
7,310
$32.12
$234.80K
Cline Christopher R.
3 Feb 2026
CHIEF FINANCIAL OFFICER
Sell
7,242
$32.12
$232.61K
Inrig Jula
3 Feb 2026
CHIEF MEDICAL OFFICER
Sell
6,956
$32.12
$223.43K
Dube Eric M
3 Feb 2026
CHIEF EXECUTIVE OFFICER
Sold on a plan
33,635
$32.70
$1.10M
Dube Eric M
3 Feb 2026
CHIEF EXECUTIVE OFFICER
Sold on a plan
66,452
$32.06
$2.13M
Dube Eric M
27 Jan 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
51,865
$30.10
$1.56M
Dube Eric M
23 Jan 2026
CHIEF EXECUTIVE OFFICER
Sold after exercise
8,135
$30.01
$244.15K
REED ELIZABETH E
20 Jan 2026
Chief Legal Officer and GC
Sold after exercise
10,000
$27.34
$273.42K
Inrig Jula
6 Jan 2026
CHIEF MEDICAL OFFICER
Sold on a plan
445
$37.75
$16.80K
Inrig Jula
5 Jan 2026
CHIEF MEDICAL OFFICER
Sold on a plan
2,031
$40.18
$81.61K
Calvin Sandra
24 Dec 2025
SVP, CHIEF ACCOUNTING OFFICER
Sold on a plan
7,402
$40.00
$296.08K
Inrig Jula
24 Dec 2025
CHIEF MEDICAL OFFICER
Sold after exercise
15,000
$42.00
$630.00K
ROTE WILLIAM E.
24 Dec 2025
Chief Research Officer
Sold after exercise
60,000
$40.10
$2.41M
Heerma Peter
24 Dec 2025
CHIEF COMMERCIAL OFFICER
Sold on a plan
4,980
$40.00
$199.20K
Calvin Sandra
15 Dec 2025
SVP, CHIEF ACCOUNTING OFFICER
Sold on a plan
2,910
$36.00
$104.76K
Cline Christopher R.
1 Dec 2025
CHIEF FINANCIAL OFFICER
Sold after exercise
20,000
$35.01
$700.20K
Calvin Sandra
4 Nov 2025
SVP, CHIEF ACCOUNTING OFFICER
Sold after exercise
67,115
$36.00
$2.42M
Heerma Peter
31 Oct 2025
CHIEF COMMERCIAL OFFICER
Sold on a plan
5,591
$35.00
$195.69K
Coughlin Timothy
31 Oct 2025
Director
Sold after exercise
18,000
$35.03
$630.60K
Dube Eric M
29 Oct 2025
CHIEF EXECUTIVE OFFICER
Sold after exercise
27,128
$30.12
$817.07K
Heerma Peter
28 Oct 2025
CHIEF COMMERCIAL OFFICER
Sold on a plan
2,662
$30.00
$79.86K
Dube Eric M
28 Oct 2025
CHIEF EXECUTIVE OFFICER
Sold after exercise
92,872
$30.38
$2.82M
REED ELIZABETH E
22 Sep 2025
Chief Legal Officer and GC
Sold after exercise
10,000
$25.00
$250.00K
