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Stocks · Health care · Pharmaceutical Preparations

Amylyx Pharmaceuticals, Inc.

AMLX Clue Score40
United States Fiscal year ends December CIK 0001658551
$28.14 +3.46% Close, 9 Oct 2026
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Price $28.14 +58.98% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 7 Jan 2022. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2021Revenue0.3Operating income−82.7Net income−87.9EPS, diluted−13.35Fiscal year 2022Revenue22.2 +7,700.0%Operating income−201.3Net income−198.4EPS, diluted−3.39Fiscal year 2023Revenue380.8 +1,612.9%Operating income38.8Net income49.3EPS, diluted0.70Fiscal year 2024Revenue87.4 −77.1%Operating income−314.7Net income−301.7 −712.4%EPS, diluted−4.43Fiscal year 2025Revenue0.0 −100.0%Operating income−153.3Net income−144.7EPS, diluted−1.53
FY2021FY2022FY2023FY2024FY2025
Revenue 0.3 22.2 380.8 87.4 0.0
Growth +7,700.0% +1,612.9% −77.1% −100.0%
Operating income −82.7 −201.3 38.8 −314.7 −153.3
Net income −87.9 −198.4 49.3 −301.7 −144.7
Growth −712.4%
EPS, diluted −13.35 −3.39 0.70 −4.43 −1.53

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2021Operating margin−29,013.3%Net margin−30,853.0%Free cash flow margin−26,369.1%Fiscal year 2022Operating margin−905.7%Net margin−892.4%Free cash flow margin−820.5%Fiscal year 2023Operating margin10.2%Net margin12.9%Free cash flow margin2.8%Fiscal year 2024Operating margin−360.2%Net margin−345.4%Free cash flow margin−192.1%Fiscal year 2025
FY2021FY2022FY2023FY2024FY2025
Operating margin −29,013.3% −905.7% 10.2% −360.2% n/a
Net margin −30,853.0% −892.4% 12.9% −345.4% n/a
Free cash flow margin −26,369.1% −820.5% 2.8% −192.1% n/a

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2021Operating cash flow−74.8Capital expenditure−0.4Free cash flow−75.2Fiscal year 2022Operating cash flow−179.9Capital expenditure−2.5Free cash flow−182.4Fiscal year 2023Operating cash flow11.9Capital expenditure−1.2Free cash flow10.7Fiscal year 2024Operating cash flow−167.6Capital expenditure−0.2Free cash flow−167.8 −1,671.5%Fiscal year 2025Operating cash flow−123.3Capital expenditure−0.1Free cash flow−123.5
FY2021FY2022FY2023FY2024FY2025
Operating cash flow −74.8 −179.9 11.9 −167.6 −123.3
Capital expenditure −0.4 −2.5 −1.2 −0.2 −0.1
Free cash flow −75.2 −182.4 10.7 −167.8 −123.5
Growth −1,671.5%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2021Cash50.2Shareholders’ equity−151.2Fiscal year 2022Cash62.5Shareholders’ equity340.6Fiscal year 2023Cash170.2Shareholders’ equity433.4Fiscal year 2024Cash77.4Shareholders’ equity164.8Fiscal year 2025Cash226.7Shareholders’ equity305.3
FY2021FY2022FY2023FY2024FY2025
Cash 50.2 62.5 170.2 77.4 226.7
Shareholders’ equity −151.2 340.6 433.4 164.8 305.3

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Income statement

In millions of USD, except per-share figures; shares in millions. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2021 31 Dec 2021 FY2022† 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Revenue and profit
0.3 22.2 380.8 87.4 0.0
Growth +7,700.0% +1,612.9% −77.1% −100.0%
n/a 3.0 25.4 6.0 0.0
44.0 93.5 128.2 104.1 90.4
38.9 127.1 188.4 114.3 62.9
−82.7 −201.3 38.8 −314.7 −153.3
Growth −911.1%
−87.9 −197.6 54.3 −302.1 −144.7
n/a 0.8 5.0 −0.4 0.0
−87.9 −198.4 49.3 −301.7 −144.7
Growth −712.4%
Per share
−13.35 −3.39 0.73 −4.43 −1.53
−13.35 −3.39 0.70 −4.43 −1.53
Growth −732.9%
6.6 58.5 67.2 68.1 94.6
6.6 58.5 70.0 68.1 94.6
Growth +788.1% +19.7% −2.6% +38.8%

† The diluted share count jumps at 2022, so per-share figures either side of that column are not comparable. Usually a split, but the break lands on the restatement boundary rather than on the split date, because every column is that period’s latest filing.

Five years in brief

Worked out from the figures above, not from a press release
  • A net loss in 4 of 5 years on file.