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Stocks · Health care · Pharmaceutical Preparations

Amylyx Pharmaceuticals, Inc.

AMLX Clue Score40
United States Fiscal year ends December CIK 0001658551
$28.14 +3.46% Close, 9 Oct 2026
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Price $28.14 +58.98% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 7 Jan 2022. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2021Revenue0.3Operating income−82.7Net income−87.9EPS, diluted−13.35Fiscal year 2022Revenue22.2 +7,700.0%Operating income−201.3Net income−198.4EPS, diluted−3.39Fiscal year 2023Revenue380.8 +1,612.9%Operating income38.8Net income49.3EPS, diluted0.70Fiscal year 2024Revenue87.4 −77.1%Operating income−314.7Net income−301.7 −712.4%EPS, diluted−4.43Fiscal year 2025Revenue0.0 −100.0%Operating income−153.3Net income−144.7EPS, diluted−1.53
FY2021FY2022FY2023FY2024FY2025
Revenue 0.3 22.2 380.8 87.4 0.0
Growth +7,700.0% +1,612.9% −77.1% −100.0%
Operating income −82.7 −201.3 38.8 −314.7 −153.3
Net income −87.9 −198.4 49.3 −301.7 −144.7
Growth −712.4%
EPS, diluted −13.35 −3.39 0.70 −4.43 −1.53

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2021Operating margin−29,013.3%Net margin−30,853.0%Free cash flow margin−26,369.1%Fiscal year 2022Operating margin−905.7%Net margin−892.4%Free cash flow margin−820.5%Fiscal year 2023Operating margin10.2%Net margin12.9%Free cash flow margin2.8%Fiscal year 2024Operating margin−360.2%Net margin−345.4%Free cash flow margin−192.1%Fiscal year 2025
FY2021FY2022FY2023FY2024FY2025
Operating margin −29,013.3% −905.7% 10.2% −360.2% n/a
Net margin −30,853.0% −892.4% 12.9% −345.4% n/a
Free cash flow margin −26,369.1% −820.5% 2.8% −192.1% n/a

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2021Operating cash flow−74.8Capital expenditure−0.4Free cash flow−75.2Fiscal year 2022Operating cash flow−179.9Capital expenditure−2.5Free cash flow−182.4Fiscal year 2023Operating cash flow11.9Capital expenditure−1.2Free cash flow10.7Fiscal year 2024Operating cash flow−167.6Capital expenditure−0.2Free cash flow−167.8 −1,671.5%Fiscal year 2025Operating cash flow−123.3Capital expenditure−0.1Free cash flow−123.5
FY2021FY2022FY2023FY2024FY2025
Operating cash flow −74.8 −179.9 11.9 −167.6 −123.3
Capital expenditure −0.4 −2.5 −1.2 −0.2 −0.1
Free cash flow −75.2 −182.4 10.7 −167.8 −123.5
Growth −1,671.5%

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2021Cash50.2Shareholders’ equity−151.2Fiscal year 2022Cash62.5Shareholders’ equity340.6Fiscal year 2023Cash170.2Shareholders’ equity433.4Fiscal year 2024Cash77.4Shareholders’ equity164.8Fiscal year 2025Cash226.7Shareholders’ equity305.3
FY2021FY2022FY2023FY2024FY2025
Cash 50.2 62.5 170.2 77.4 226.7
Shareholders’ equity −151.2 340.6 433.4 164.8 305.3

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
−29,013.3% −905.7% 10.2% −360.2% n/a
−30,853.0% −888.9% 14.3% −345.8% n/a
−30,853.0% −892.4% 12.9% −345.4% n/a
−26,369.1% −820.5% 2.8% −192.1% n/a
Spending
15,452.6% 420.4% 33.7% 119.1% n/a
13,660.7% 571.9% 49.5% 130.9% n/a
123.9% 11.4% 0.3% 0.2% n/a
n/a n/a 9.3% n/a n/a
Returns
n/a −58.2% 11.4% −183.1% −47.4%
−83.3% −50.7% 9.5% −155.8% −43.5%
Balance and payout
16.5% 13.0% 16.2% 14.9% 8.2%