InsiderClue
Stocks · Health care · Pharmaceutical Preparations

Ultragenyx Pharmaceutical Inc.

RARE Clue Score44
United States Fiscal year ends December CIK 0001515673
$15.48 +1.24% Close, 9 Oct 2026
Alert on the numbers Alert on insider trades
Price $15.48 −80.89% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 12 Oct 2016. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2016Revenue0.1Operating income−248.0Net income−245.9Fiscal year 2017Revenue2.6 +1,863.9%Operating income−328.9Net income−302.1Fiscal year 2018Revenue51.5 +1,871.5%Operating income−371.4Net income−197.6Fiscal year 2019Revenue103.7 +101.4%Operating income−424.2Net income−402.7Fiscal year 2020Revenue271.0 +161.3%Operating income−330.1Net income−186.6EPS, diluted−3.07Fiscal year 2021Revenue351.4 +29.7%Operating income−381.7Net income−454.0EPS, diluted−6.70Fiscal year 2022Revenue363.3 +3.4%Operating income−648.9Net income−707.4EPS, diluted−10.12Fiscal year 2023Revenue434.0 +19.5%Operating income−569.0Net income−607.0EPS, diluted−8.25Fiscal year 2024Revenue560.0 +29.0%Operating income−536.0Net income−569.0EPS, diluted−6.29Fiscal year 2025Revenue673.0 +20.2%Operating income−535.0Net income−575.0EPS, diluted−5.83
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue 0.1 2.6 51.5 103.7 271.0 351.4 363.3 434.0 560.0 673.0
Growth +1,863.9% +1,871.5% +101.4% +161.3% +29.7% +3.4% +19.5% +29.0% +20.2%
Operating income −248.0 −328.9 −371.4 −424.2 −330.1 −381.7 −648.9 −569.0 −536.0 −535.0
Net income −245.9 −302.1 −197.6 −402.7 −186.6 −454.0 −707.4 −607.0 −569.0 −575.0
Growth
EPS, diluted n/a n/a n/a n/a −3.07 −6.70 −10.12 −8.25 −6.29 −5.83
Growth

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2016Operating margin−186,471.4%Net margin−184,867.7%Free cash flow margin−128,694.0%Fiscal year 2017Operating margin−12,593.5%Net margin−11,567.3%Free cash flow margin−9,825.3%Fiscal year 2018Operating margin−721.2%Net margin−383.7%Free cash flow margin−572.2%Fiscal year 2019Operating margin−409.0%Net margin−388.3%Free cash flow margin−357.0%Fiscal year 2020Operating margin−121.8%Net margin−68.8%Free cash flow margin−65.0%Fiscal year 2021Operating margin−108.6%Net margin−129.2%Free cash flow margin−117.2%Fiscal year 2022Operating margin−178.6%Net margin−194.7%Free cash flow margin−136.7%Fiscal year 2023Operating margin−131.1%Net margin−139.9%Free cash flow margin−119.6%Fiscal year 2024Operating margin−95.7%Net margin−101.6%Free cash flow margin−75.2%Fiscal year 2025Operating margin−79.5%Net margin−85.4%Free cash flow margin−70.1%
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating margin −186,471.4% −12,593.5% −721.2% −409.0% −121.8% −108.6% −178.6% −131.1% −95.7% −79.5%
Net margin −184,867.7% −11,567.3% −383.7% −388.3% −68.8% −129.2% −194.7% −139.9% −101.6% −85.4%
Free cash flow margin −128,694.0% −9,825.3% −572.2% −357.0% −65.0% −117.2% −136.7% −119.6% −75.2% −70.1%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2016Operating cash flow−161.0Capital expenditure−10.2Free cash flow−171.2Fiscal year 2017Operating cash flow−253.8Capital expenditure−2.8Free cash flow−256.6Fiscal year 2018Operating cash flow−290.6Capital expenditure−4.1Free cash flow−294.6Fiscal year 2019Operating cash flow−345.4Capital expenditure−24.8Free cash flow−370.2Fiscal year 2020Operating cash flow−132.2Capital expenditure−43.9Free cash flow−176.1Fiscal year 2021Operating cash flow−338.7Capital expenditure−73.1Free cash flow−411.8Fiscal year 2022Operating cash flow−380.5Capital expenditure−116.1Free cash flow−496.6Fiscal year 2023Operating cash flow−475.0Capital expenditure−44.0Free cash flow−519.0Fiscal year 2024Operating cash flow−414.0Capital expenditure−7.0Free cash flow−421.0Fiscal year 2025Operating cash flow−466.0Capital expenditure−6.0Free cash flow−472.0
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow −161.0 −253.8 −290.6 −345.4 −132.2 −338.7 −380.5 −475.0 −414.0 −466.0
Capital expenditure −10.2 −2.8 −4.1 −24.8 −43.9 −73.1 −116.1 −44.0 −7.0 −6.0
Free cash flow −171.2 −256.6 −294.6 −370.2 −176.1 −411.8 −496.6 −519.0 −421.0 −472.0
Growth

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2016Cash161.1Shareholders’ equity474.0Fiscal year 2017Cash100.5Shareholders’ equity383.5Fiscal year 2018Cash113.4Shareholders’ equity608.9Fiscal year 2019Cash433.6Shareholders’ equity653.8Fiscal year 2020Cash713.5Shareholders’ equity1,154.4Fiscal year 2021Cash307.6Shareholders’ equity922.6Fiscal year 2022Cash132.9Shareholders’ equity352.0Fiscal year 2023Cash214.0Shareholders’ equity275.0Fiscal year 2024Cash174.0Shareholders’ equity255.0Fiscal year 2025Cash421.0Shareholders’ equity−80.0
FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash 161.1 100.5 113.4 433.6 713.5 307.6 132.9 214.0 174.0 421.0
Shareholders’ equity 474.0 383.5 608.9 653.8 1,154.4 922.6 352.0 275.0 255.0 −80.0

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2016 31 Dec 2016 FY2017 31 Dec 2017 FY2018 31 Dec 2018 FY2019 31 Dec 2019 FY2020 31 Dec 2020 FY2021 31 Dec 2021 FY2022 31 Dec 2022 FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
−186,471.4% −12,593.5% −721.2% −409.0% −121.8% −108.6% −178.6% −131.1% −95.7% −79.5%
−184,841.4% −12,187.5% −382.7% −385.1% −68.4% −128.9% −193.1% −140.3% −101.3% −84.8%
−184,867.7% −11,567.3% −383.7% −388.3% −68.8% −129.2% −194.7% −139.9% −101.6% −85.4%
−128,694.0% −9,825.3% −572.2% −357.0% −65.0% −117.2% −136.7% −119.6% −75.2% −70.1%
Spending
137,747.4% 8,868.5% 570.9% 344.6% 152.0% 141.5% 194.3% 149.3% 124.6% 111.4%
48,824.1% 3,825.0% 248.0% 155.7% 67.5% 62.6% 76.6% 71.4% 57.3% 51.9%
7,660.2% 106.9% 7.9% 23.9% 16.2% 20.8% 32.0% 10.1% 1.3% 0.9%
Returns
−51.9% −78.8% −32.5% −61.6% −16.2% −49.2% −201.0% −220.7% −223.1% n/a
−45.5% −61.6% −27.5% −35.5% −10.6% −29.8% −45.8% −40.7% −37.9% −37.5%
Balance and payout
12.3% 21.9% 15.4% 42.4% 34.4% 39.4% 77.2% 81.5% 82.6% 104.8%