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Stocks · Health care · Pharmaceutical Preparations

Septerna, Inc.

SEPN Clue Score47
United States Fiscal year ends December CIK 0001984086
$38.37 +3.98% Close, 9 Oct 2026
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Price $38.37 +65.82% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 25 Oct 2024. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2023Revenue0.2Operating income2.1Net income4.2EPS, diluted0.29Fiscal year 2024Revenue1.1 +611.9%Operating income−80.8Net income−71.8 −1,817.7%EPS, diluted−7.26Fiscal year 2025Revenue46.0 +4,174.5%Operating income−68.3Net income−48.9EPS, diluted−1.10
FY2023FY2024FY2025
Revenue 0.2 1.1 46.0
Growth +611.9% +4,174.5%
Operating income 2.1 −80.8 −68.3
Net income 4.2 −71.8 −48.9
Growth −1,817.7%
EPS, diluted 0.29 −7.26 −1.10

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2023Operating margin1,374.2%Net margin2,768.2%Free cash flow margin−27,550.3%Fiscal year 2024Operating margin−7,518.4%Net margin−6,678.9%Free cash flow margin−6,471.9%Fiscal year 2025Operating margin−148.6%Net margin−106.4%Free cash flow margin238.7%
FY2023FY2024FY2025
Operating margin 1,374.2% −7,518.4% −148.6%
Net margin 2,768.2% −6,678.9% −106.4%
Free cash flow margin −27,550.3% −6,471.9% 238.7%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2023Operating cash flow−38.7Capital expenditure−2.9Free cash flow−41.6Fiscal year 2024Operating cash flow−67.5Capital expenditure−2.1Free cash flow−69.6Fiscal year 2025Operating cash flow110.2Capital expenditure−0.5Free cash flow109.7
FY2023FY2024FY2025
Operating cash flow −38.7 −67.5 110.2
Capital expenditure −2.9 −2.1 −0.5
Free cash flow −41.6 −69.6 109.7
Growth

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2023Cash88.5Shareholders’ equity−38.4Fiscal year 2024Cash238.2Shareholders’ equity420.0Fiscal year 2025Cash120.7Shareholders’ equity381.9
FY2023FY2024FY2025
Cash 88.5 238.2 120.7
Shareholders’ equity −38.4 420.0 381.9

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Income statement

In millions of USD, except per-share figures; shares in millions. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2023 31 Dec 2023 FY2024† 31 Dec 2024 FY2025† 31 Dec 2025
Revenue and profit
0.2 1.1 46.0
Growth +611.9% +4,174.5%
36.0 65.3 97.6
9.7 16.6 29.2
2.1 −80.8 −68.3
Growth −3,995.1%
−48.9 −72.3 −48.9
0.7 −0.5 0.0
4.2 −71.8 −48.9
Growth −1,817.7%
Per share
0.29 −7.26 −1.10
0.29 −7.26 −1.10
Growth −2,603.4%
1.9 9.9 44.3
2.2 9.9 44.3
Growth +354.3% +347.5%

† The diluted share count jumps at 2024 and 2025, so per-share figures either side of that column are not comparable. Usually a split, but the break lands on the restatement boundary rather than on the split date, because every column is that period’s latest filing.

Five years in brief

Worked out from the figures above, not from a press release
  • A net loss in 2 of 3 years on file.