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Stocks · Health care · Pharmaceutical Preparations

Septerna, Inc.

SEPN Clue Score47
United States Fiscal year ends December CIK 0001984086
$38.37 +3.98% Close, 9 Oct 2026
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Price $38.37 +65.82% Close, 9 Oct 2026

Closing prices at the end of each trading day, from 25 Oct 2024. Not a live quote. Adjusted for share splits, so the line has no step at a split; dividends are not added back. P/E and P/FCF are the market value over the last full fiscal year's net income or free cash flow, as public on each day, so they step once a year when the annual report comes out. A hatched band marks a stretch with none: a year of net loss, or of cash burnt.

Revenue and profit

What the business sells, and what is left of it. Point at a year for the detail.
RevenueOperating incomeNet income
Fiscal year 2023Revenue0.2Operating income2.1Net income4.2EPS, diluted0.29Fiscal year 2024Revenue1.1 +611.9%Operating income−80.8Net income−71.8 −1,817.7%EPS, diluted−7.26Fiscal year 2025Revenue46.0 +4,174.5%Operating income−68.3Net income−48.9EPS, diluted−1.10
FY2023FY2024FY2025
Revenue 0.2 1.1 46.0
Growth +611.9% +4,174.5%
Operating income 2.1 −80.8 −68.3
Net income 4.2 −71.8 −48.9
Growth −1,817.7%
EPS, diluted 0.29 −7.26 −1.10

Margins

How much of each dollar of revenue it keeps. Point at a year for the detail.
Operating marginNet margin
Fiscal year 2023Operating margin1,374.2%Net margin2,768.2%Free cash flow margin−27,550.3%Fiscal year 2024Operating margin−7,518.4%Net margin−6,678.9%Free cash flow margin−6,471.9%Fiscal year 2025Operating margin−148.6%Net margin−106.4%Free cash flow margin238.7%
FY2023FY2024FY2025
Operating margin 1,374.2% −7,518.4% −148.6%
Net margin 2,768.2% −6,678.9% −106.4%
Free cash flow margin −27,550.3% −6,471.9% 238.7%

Cash flow

The cash the business makes, what it reinvests, and what it hands back. Point at a year for the detail.
Operating cash flowCapital expenditureFree cash flow
Fiscal year 2023Operating cash flow−38.7Capital expenditure−2.9Free cash flow−41.6Fiscal year 2024Operating cash flow−67.5Capital expenditure−2.1Free cash flow−69.6Fiscal year 2025Operating cash flow110.2Capital expenditure−0.5Free cash flow109.7
FY2023FY2024FY2025
Operating cash flow −38.7 −67.5 110.2
Capital expenditure −2.9 −2.1 −0.5
Free cash flow −41.6 −69.6 109.7
Growth

Balance sheet

What it holds against what it owes, at each year end. Point at a year for the detail.
Cash
Fiscal year 2023Cash88.5Shareholders’ equity−38.4Fiscal year 2024Cash238.2Shareholders’ equity420.0Fiscal year 2025Cash120.7Shareholders’ equity381.9
FY2023FY2024FY2025
Cash 88.5 238.2 120.7
Shareholders’ equity −38.4 420.0 381.9

In millions of USD, except per-share figures and ratios. Fiscal years, as last filed with the SEC.

Financial statements FY2025 · 10-K

Ratios

Percentages worked out from the filed figures; debt to equity in times. Fiscal years ending December, each column as last filed with the SEC.
Click a line to chart it
Fiscal year FY2023 31 Dec 2023 FY2024 31 Dec 2024 FY2025 31 Dec 2025
Margins
1,374.2% −7,518.4% −148.6%
−32,362.3% −6,725.2% −106.3%
2,768.2% −6,678.9% −106.4%
−27,550.3% −6,471.9% 238.7%
Spending
23,827.2% 6,077.9% 212.4%
6,438.4% 1,540.6% 63.5%
1,906.0% 195.6% 1.1%
Returns
n/a −17.1% −12.8%
3.2% −15.7% −8.2%
Balance and payout
15.3% 8.0% 35.9%